ID   H7C4F8_HUMAN            Unreviewed;       277 AA.
AC   H7C4F8;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   05-DEC-2018, entry version 38.
DE   SubName: Full=T-lymphocyte activation antigen CD86 {ECO:0000313|Ensembl:ENSP00000417195};
DE   Flags: Fragment;
GN   Name=CD86 {ECO:0000313|Ensembl:ENSP00000417195};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000417195, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000417195, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16641997; DOI=10.1038/nature04728;
RA   Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R.,
RA   Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R.,
RA   Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V.,
RA   Hume J., Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R.,
RA   Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B.,
RA   Nazareth L.V., Scott G., Sodergren E., Song X.Z., Steffen D., Wei S.,
RA   Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q.,
RA   Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z.,
RA   Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C.,
RA   Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G.,
RA   Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B.,
RA   Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R.,
RA   Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J.,
RA   Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O., Palmeiri A.,
RA   Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B.,
RA   Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H.,
RA   Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J.,
RA   Wang J., Wang Q., Williams G.A., Wong G.K., Yao Z., Zhang J.,
RA   Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H.,
RA   Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G.,
RA   Gibbs R.A.;
RT   "The DNA sequence, annotation and analysis of human chromosome 3.";
RL   Nature 440:1194-1198(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000417195}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
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DR   EMBL; AC068630; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; H7C4F8; -.
DR   PeptideAtlas; H7C4F8; -.
DR   PRIDE; H7C4F8; -.
DR   Ensembl; ENST00000478741; ENSP00000417195; ENSG00000114013.
DR   UCSC; uc062mzo.1; human.
DR   EuPathDB; HostDB:ENSG00000114013.15; -.
DR   HGNC; HGNC:1705; CD86.
DR   OpenTargets; ENSG00000114013; -.
DR   GeneTree; ENSGT00940000161500; -.
DR   ChiTaRS; CD86; human.
DR   Proteomes; UP000005640; Chromosome 3.
DR   Bgee; ENSG00000114013; Expressed in 172 organ(s), highest expression level in leukocyte.
DR   ExpressionAtlas; H7C4F8; baseline and differential.
DR   CDD; cd16087; IgV_CD86; 1.
DR   Gene3D; 2.60.40.10; -; 2.
DR   InterPro; IPR037677; CD86_IgV.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR013106; Ig_V-set.
DR   Pfam; PF13895; Ig_2; 1.
DR   Pfam; PF07686; V-set; 1.
DR   SMART; SM00409; IG; 1.
DR   SMART; SM00406; IGv; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:H7C4F8,
KW   ECO:0000213|PeptideAtlas:H7C4F8};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     26       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        27    277       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003608284.
FT   DOMAIN       29    127       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   NON_TER       1      1       {ECO:0000313|Ensembl:ENSP00000417195}.
SQ   SEQUENCE   277 AA;  31505 MW;  5DA998A5B6421968 CRC64;
     XTMGLSNILF VMAFLLSGAA PLKIQAYFNE TADLPCQFAN SQNQSLSELV VFWQDQENLV
     LNEVYLGKEK FDSVHSKYMG RTSFDSDSWT LRLHNLQIKD KGLYQCIIHH KKPTGMIRIH
     QMNSELSVLA NFSQPEIVPI SNITENVYIN LTCSSIHGYP EPKKMSVLLR TKNSTIEYDG
     VMQKSQDNVT ELYDVSISLS VSFPDVTSNM TIFCILETDK TRLLSSPFSI GTNTMEREES
     EQTKKREKIH IPERSDEAQR VFKSSKTSSC DKSDTCF
//