ID   H7C3B2_HUMAN            Unreviewed;       304 AA.
AC   H7C3B2;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   16-JAN-2019, entry version 43.
DE   SubName: Full=Inactive C-alpha-formylglycine-generating enzyme 2 {ECO:0000313|Ensembl:ENSP00000410796};
DE   Flags: Fragment;
GN   Name=SUMF2 {ECO:0000313|Ensembl:ENSP00000410796};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000410796, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000410796, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12853948; DOI=10.1038/nature01782;
RA   Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H.,
RA   Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R.,
RA   Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E.,
RA   Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Cordes M., Du H.,
RA   Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A.,
RA   Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J.,
RA   Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A.,
RA   Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S.,
RA   Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M.,
RA   Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C.,
RA   Latreille P., Miller N., Johnson D., Murray J., Woessner J.P.,
RA   Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J.,
RA   Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L.,
RA   Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R.,
RA   Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E.,
RA   Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K.,
RA   Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S.,
RA   Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M.,
RA   Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R.,
RA   Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D.,
RA   Waterston R.H., Wilson R.K.;
RT   "The DNA sequence of human chromosome 7.";
RL   Nature 424:157-164(2003).
RN   [2] {ECO:0000213|PubMed:21269460}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA   Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P.,
RA   Burckstummer T., Bennett K.L., Superti-Furga G., Colinge J.;
RT   "Initial characterization of the human central proteome.";
RL   BMC Syst. Biol. 5:17-17(2011).
RN   [3] {ECO:0000313|Ensembl:ENSP00000410796}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
RN   [4] {ECO:0000213|PubMed:25944712}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=25944712;
RA   Vaca Jacome A.S., Rabilloud T., Schaeffer-Reiss C., Rompais M.,
RA   Ayoub D., Lane L., Bairoch A., Van Dorsselaer A., Carapito C.;
RT   "N-terminome analysis of the human mitochondrial proteome.";
RL   Proteomics 15:2519-2524(2015).
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DR   EMBL; AC092101; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; H7C3B2; -.
DR   EPD; H7C3B2; -.
DR   jPOST; H7C3B2; -.
DR   MaxQB; H7C3B2; -.
DR   PeptideAtlas; H7C3B2; -.
DR   PRIDE; H7C3B2; -.
DR   Ensembl; ENST00000451338; ENSP00000410796; ENSG00000129103.
DR   UCSC; uc064dve.1; human.
DR   EuPathDB; HostDB:ENSG00000129103.17; -.
DR   HGNC; HGNC:20415; SUMF2.
DR   OpenTargets; ENSG00000129103; -.
DR   GeneTree; ENSGT00390000008983; -.
DR   Proteomes; UP000005640; Chromosome 7.
DR   Bgee; ENSG00000129103; Expressed in 196 organ(s), highest expression level in right uterine tube.
DR   ExpressionAtlas; H7C3B2; baseline and differential.
DR   InterPro; IPR016187; CTDL_fold.
DR   InterPro; IPR005532; SUMF_dom.
DR   Pfam; PF03781; FGE-sulfatase; 1.
DR   SUPFAM; SSF56436; SSF56436; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|EPD:H7C3B2,
KW   ECO:0000213|MaxQB:H7C3B2, ECO:0000213|PeptideAtlas:H7C3B2};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     22       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        23    304       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003608465.
FT   DOMAIN       24    304       FGE-sulfatase.
FT                                {ECO:0000259|Pfam:PF03781}.
FT   NON_TER       1      1       {ECO:0000313|Ensembl:ENSP00000410796}.
FT   NON_TER     304    304       {ECO:0000313|Ensembl:ENSP00000410796}.
SQ   SEQUENCE   304 AA;  34115 MW;  A240EC7EE4F8C64C CRC64;
     HGLPLLPLLS LLVGAWLKLG NGQATSMVQL QGGRFLMGTN SPDSRDGDGP VREATVKPFA
     IDIFPVTNKD FRDFVREKKY RTEAEMFGWS FVFEDFVSDE LRNKATQPMK SGRCLCWAGA
     SCSRSPSFSQ SVLWWLPVEK AFWRQPAGPG SGIRERLEHP VLHVSWNDAR AYCAWRGKRL
     PTEEEWEFAA RGGLKGQVYP WGNWFQPNRT NLWQGKFPKG DKAEDGFHGV SPVNAFPAQN
     NYGLYDLLGN VWEWTASPYQ AAEQDMRVLR GASWIDTADG SANHRARVTT RMGNTPDSAS
     DNLG
//