ID   H7C382_HUMAN            Unreviewed;       117 AA.
AC   H7C382;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   16-JAN-2019, entry version 31.
DE   SubName: Full=1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase {ECO:0000313|Ensembl:ENSP00000410178};
DE   Flags: Fragment;
GN   Name=ADI1 {ECO:0000313|Ensembl:ENSP00000410178};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000410178, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000410178, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15815621; DOI=10.1038/nature03466;
RA   Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H.,
RA   Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M.,
RA   Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E.,
RA   Kremitzki C., Oddy L., Du H., Sun H., Bradshaw-Cordum H., Ali J.,
RA   Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C.,
RA   Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J.,
RA   Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A.,
RA   Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K.,
RA   Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M.,
RA   Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K.,
RA   McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C.,
RA   Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N.,
RA   Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M.,
RA   Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E.,
RA   Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P.,
RA   Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A.,
RA   Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A.,
RA   Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T.,
RA   Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D.,
RA   Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X.,
RA   McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C.,
RA   Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S.,
RA   Miller W., Eichler E.E., Bork P., Suyama M., Torrents D.,
RA   Waterston R.H., Wilson R.K.;
RT   "Generation and annotation of the DNA sequences of human chromosomes 2
RT   and 4.";
RL   Nature 434:724-731(2005).
RN   [2] {ECO:0000313|Ensembl:ENSP00000410178}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
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DR   EMBL; AC114810; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC231981; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; H7C382; -.
DR   EPD; H7C382; -.
DR   jPOST; H7C382; -.
DR   MaxQB; H7C382; -.
DR   PeptideAtlas; H7C382; -.
DR   PRIDE; H7C382; -.
DR   Ensembl; ENST00000415131; ENSP00000410178; ENSG00000182551.
DR   UCSC; uc061ges.1; human.
DR   EuPathDB; HostDB:ENSG00000182551.13; -.
DR   HGNC; HGNC:30576; ADI1.
DR   OpenTargets; ENSG00000182551; -.
DR   GeneTree; ENSGT00390000008195; -.
DR   ChiTaRS; ADI1; human.
DR   Proteomes; UP000005640; Chromosome 2.
DR   Bgee; ENSG00000182551; Expressed in 236 organ(s), highest expression level in liver.
DR   ExpressionAtlas; H7C382; baseline and differential.
DR   Gene3D; 2.60.120.10; -; 1.
DR   InterPro; IPR014710; RmlC-like_jellyroll.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|EPD:H7C382,
KW   ECO:0000213|MaxQB:H7C382, ECO:0000213|PeptideAtlas:H7C382};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     29       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        30    117       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003608283.
FT   NON_TER       1      1       {ECO:0000313|Ensembl:ENSP00000410178}.
SQ   SEQUENCE   117 AA;  12297 MW;  88F3A0C40570232A CRC64;
     XRWECCAFSP GPACVVALAV ASLPLNCAAS ADSKRGRWAR DSSTCASRRV CGAAGDVRGD
     SCPSVAASVA PACDPGGQNY TKAMRLFVGE PVWTAYNRPA DHFEARGQYV KFLAQTA
//