ID   H7C268_HUMAN            Unreviewed;       258 AA.
AC   H7C268;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   16-JAN-2019, entry version 34.
DE   SubName: Full=Transmembrane protein 168 {ECO:0000313|Ensembl:ENSP00000404253};
DE   Flags: Fragment;
GN   Name=TMEM168 {ECO:0000313|Ensembl:ENSP00000404253};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000404253, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000404253, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12853948; DOI=10.1038/nature01782;
RA   Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H.,
RA   Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R.,
RA   Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E.,
RA   Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Cordes M., Du H.,
RA   Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A.,
RA   Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J.,
RA   Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A.,
RA   Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S.,
RA   Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M.,
RA   Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C.,
RA   Latreille P., Miller N., Johnson D., Murray J., Woessner J.P.,
RA   Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J.,
RA   Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L.,
RA   Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R.,
RA   Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E.,
RA   Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K.,
RA   Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S.,
RA   Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M.,
RA   Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R.,
RA   Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D.,
RA   Waterston R.H., Wilson R.K.;
RT   "The DNA sequence of human chromosome 7.";
RL   Nature 424:157-164(2003).
RN   [2] {ECO:0000313|Ensembl:ENSP00000404253}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
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DR   EMBL; AC079621; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; H7C268; -.
DR   jPOST; H7C268; -.
DR   MaxQB; H7C268; -.
DR   PeptideAtlas; H7C268; -.
DR   PRIDE; H7C268; -.
DR   Ensembl; ENST00000418785; ENSP00000404253; ENSG00000146802.
DR   UCSC; uc064hec.1; human.
DR   EuPathDB; HostDB:ENSG00000146802.12; -.
DR   HGNC; HGNC:25826; TMEM168.
DR   OpenTargets; ENSG00000146802; -.
DR   eggNOG; ENOG410IF3C; Eukaryota.
DR   eggNOG; ENOG410Y9XB; LUCA.
DR   GeneTree; ENSGT00390000005941; -.
DR   Proteomes; UP000005640; Chromosome 7.
DR   Bgee; ENSG00000146802; Expressed in 223 organ(s), highest expression level in placenta.
DR   ExpressionAtlas; H7C268; baseline and differential.
DR   InterPro; IPR029713; TMEM168.
DR   PANTHER; PTHR14437; PTHR14437; 2.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|EPD:H7C268,
KW   ECO:0000213|MaxQB:H7C268, ECO:0000213|PeptideAtlas:H7C268};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     20       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        21    258       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003609195.
FT   NON_TER       1      1       {ECO:0000313|Ensembl:ENSP00000404253}.
SQ   SEQUENCE   258 AA;  29106 MW;  FB03BB036120FCE1 CRC64;
     FFSLLATAIL GAVSWQPTNG IFLSMFLIVL PLESMAHGLF HELGNCLGGT SVGYAIVIPT
     NFCSGHTHGT GEWALAGGDT LRLDTLIEWW REKNGSFCSR LIIVLDSENS TPWVKEVRKI
     NDQYIAVQGA ELIKTVDIEE ADPPQLGDFT KDWVEYNCNS SNNICWTEKG RTVKAVYGVS
     KRWSDYTLHL PTGSDVAKHW MLHFPRITYP LVHLANWLCG LNLFWICKTC FRCLKRLKMS
     WFLPTVLDTG QGFKLVKS
//