ID   H7C0F2_HUMAN            Unreviewed;       111 AA.
AC   H7C0F2;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   16-JAN-2019, entry version 36.
DE   SubName: Full=Phosphatidylinositol-glycan biosynthesis class X protein {ECO:0000313|Ensembl:ENSP00000394722};
DE   Flags: Fragment;
GN   Name=PIGX {ECO:0000313|Ensembl:ENSP00000394722};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000394722, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000394722, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16641997; DOI=10.1038/nature04728;
RA   Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R.,
RA   Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R.,
RA   Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V.,
RA   Hume J., Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R.,
RA   Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B.,
RA   Nazareth L.V., Scott G., Sodergren E., Song X.Z., Steffen D., Wei S.,
RA   Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q.,
RA   Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z.,
RA   Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C.,
RA   Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G.,
RA   Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B.,
RA   Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R.,
RA   Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J.,
RA   Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O., Palmeiri A.,
RA   Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B.,
RA   Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H.,
RA   Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J.,
RA   Wang J., Wang Q., Williams G.A., Wong G.K., Yao Z., Zhang J.,
RA   Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H.,
RA   Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G.,
RA   Gibbs R.A.;
RT   "The DNA sequence, annotation and analysis of human chromosome 3.";
RL   Nature 440:1194-1198(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000394722}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
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DR   EMBL; AC055725; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; H7C0F2; -.
DR   jPOST; H7C0F2; -.
DR   MaxQB; H7C0F2; -.
DR   PeptideAtlas; H7C0F2; -.
DR   Ensembl; ENST00000457284; ENSP00000394722; ENSG00000163964.
DR   UCSC; uc062scc.1; human.
DR   EuPathDB; HostDB:ENSG00000163964.13; -.
DR   HGNC; HGNC:26046; PIGX.
DR   OpenTargets; ENSG00000163964; -.
DR   eggNOG; ENOG410IGQT; Eukaryota.
DR   eggNOG; ENOG410Y4AX; LUCA.
DR   GeneTree; ENSGT00390000017679; -.
DR   ChiTaRS; PIGX; human.
DR   Proteomes; UP000005640; Chromosome 3.
DR   Bgee; ENSG00000163964; Expressed in 193 organ(s), highest expression level in caudate nucleus.
DR   ExpressionAtlas; H7C0F2; baseline and differential.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:InterPro.
DR   GO; GO:0006506; P:GPI anchor biosynthetic process; IEA:InterPro.
DR   InterPro; IPR013233; PIG-X/PBN1.
DR   InterPro; IPR040039; PIGX.
DR   PANTHER; PTHR28650; PTHR28650; 1.
DR   Pfam; PF08320; PIG-X; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:H7C0F2,
KW   ECO:0000213|PeptideAtlas:H7C0F2};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     20       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        21    111       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003608445.
FT   NON_TER       1      1       {ECO:0000313|Ensembl:ENSP00000394722}.
SQ   SEQUENCE   111 AA;  12407 MW;  FF3A5BE1265AA218 CRC64;
     AAAWLLLGAA TGLTRGPAAA FTAARSDAGI RAMCSEIILR QEVLKDGFHR DLLIKVKFGE
     SIEDLHTCRL LIKQDIPAGL YVDPYELASL RERNITEEKT SWRRLWLPSD N
//