ID   H7C033_HUMAN            Unreviewed;        72 AA.
AC   H7C033;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   05-DEC-2018, entry version 33.
DE   SubName: Full=Eukaryotic translation initiation factor 2-alpha kinase 1 {ECO:0000313|Ensembl:ENSP00000392734};
DE   Flags: Fragment;
GN   Name=EIF2AK1 {ECO:0000313|Ensembl:ENSP00000392734};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000392734, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000392734, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12853948; DOI=10.1038/nature01782;
RA   Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H.,
RA   Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R.,
RA   Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E.,
RA   Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Cordes M., Du H.,
RA   Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A.,
RA   Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J.,
RA   Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A.,
RA   Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S.,
RA   Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M.,
RA   Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C.,
RA   Latreille P., Miller N., Johnson D., Murray J., Woessner J.P.,
RA   Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J.,
RA   Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L.,
RA   Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R.,
RA   Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E.,
RA   Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K.,
RA   Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S.,
RA   Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M.,
RA   Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R.,
RA   Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D.,
RA   Waterston R.H., Wilson R.K.;
RT   "The DNA sequence of human chromosome 7.";
RL   Nature 424:157-164(2003).
RN   [2] {ECO:0000313|Ensembl:ENSP00000392734}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
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DR   EMBL; AC004895; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC005995; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; H7C033; -.
DR   MaxQB; H7C033; -.
DR   PeptideAtlas; H7C033; -.
DR   PRIDE; H7C033; -.
DR   Ensembl; ENST00000422786; ENSP00000392734; ENSG00000086232.
DR   UCSC; uc064bgd.1; human.
DR   EuPathDB; HostDB:ENSG00000086232.12; -.
DR   HGNC; HGNC:24921; EIF2AK1.
DR   OpenTargets; ENSG00000086232; -.
DR   eggNOG; ENOG410ISBT; Eukaryota.
DR   eggNOG; ENOG410YD23; LUCA.
DR   GeneTree; ENSGT00940000157605; -.
DR   ChiTaRS; EIF2AK1; human.
DR   Proteomes; UP000005640; Chromosome 7.
DR   Bgee; ENSG00000086232; Expressed in 226 organ(s), highest expression level in trabecular bone tissue.
DR   ExpressionAtlas; H7C033; baseline and differential.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     16       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        17     72       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003608646.
FT   COILED       42     69       {ECO:0000256|SAM:Coils}.
FT   NON_TER       1      1       {ECO:0000313|Ensembl:ENSP00000392734}.
SQ   SEQUENCE   72 AA;  7611 MW;  5EEF026F26A4BF3D CRC64;
     XLAGLTPLGV AAVASAGTGG ICWCSQRGAE GWGPTPQRRP VNLTLQMKII EQEKEIAELK
     KQLNLLSQDK GA
//