ID   H7BZV0_HUMAN            Unreviewed;       332 AA.
AC   H7BZV0;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   16-JAN-2019, entry version 36.
DE   SubName: Full=Transmembrane protein 131 {ECO:0000313|Ensembl:ENSP00000391566};
DE   Flags: Fragment;
GN   Name=TMEM131 {ECO:0000313|Ensembl:ENSP00000391566};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000391566, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000391566, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15815621; DOI=10.1038/nature03466;
RA   Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H.,
RA   Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M.,
RA   Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E.,
RA   Kremitzki C., Oddy L., Du H., Sun H., Bradshaw-Cordum H., Ali J.,
RA   Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C.,
RA   Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J.,
RA   Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A.,
RA   Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K.,
RA   Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M.,
RA   Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K.,
RA   McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C.,
RA   Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N.,
RA   Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M.,
RA   Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E.,
RA   Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P.,
RA   Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A.,
RA   Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A.,
RA   Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T.,
RA   Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D.,
RA   Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X.,
RA   McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C.,
RA   Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S.,
RA   Miller W., Eichler E.E., Bork P., Suyama M., Torrents D.,
RA   Waterston R.H., Wilson R.K.;
RT   "Generation and annotation of the DNA sequences of human chromosomes 2
RT   and 4.";
RL   Nature 434:724-731(2005).
RN   [2] {ECO:0000313|Ensembl:ENSP00000391566}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
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DR   EMBL; AC016699; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC079337; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC092591; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF456686; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF456687; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; H7BZV0; -.
DR   jPOST; H7BZV0; -.
DR   MaxQB; H7BZV0; -.
DR   PeptideAtlas; H7BZV0; -.
DR   PRIDE; H7BZV0; -.
DR   Ensembl; ENST00000418629; ENSP00000391566; ENSG00000075568.
DR   UCSC; uc061mcs.1; human.
DR   EuPathDB; HostDB:ENSG00000075568.16; -.
DR   HGNC; HGNC:30366; TMEM131.
DR   OpenTargets; ENSG00000075568; -.
DR   eggNOG; KOG3620; Eukaryota.
DR   eggNOG; ENOG410Z7NH; LUCA.
DR   GeneTree; ENSGT00530000063614; -.
DR   ChiTaRS; TMEM131; human.
DR   Proteomes; UP000005640; Chromosome 2.
DR   Bgee; ENSG00000075568; Expressed in 242 organ(s), highest expression level in bronchial epithelial cell.
DR   ExpressionAtlas; H7BZV0; baseline and differential.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR039877; TMEM131-like.
DR   InterPro; IPR022113; TMEM131-like_dom.
DR   PANTHER; PTHR22050; PTHR22050; 1.
DR   Pfam; PF12371; TMEM131_like; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:H7BZV0,
KW   ECO:0000213|PeptideAtlas:H7BZV0};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     20       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        21    332       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003608435.
FT   DOMAIN       70    152       TMEM131_like. {ECO:0000259|Pfam:PF12371}.
FT   NON_TER       1      1       {ECO:0000313|Ensembl:ENSP00000391566}.
SQ   SEQUENCE   332 AA;  36816 MW;  E2E5BC90FA6292DE CRC64;
     XGLLGALHLV MTLVVAAARA EKEAFVQSES IIEVLRFDDG GLLQTETTLG LSSYQQKSIS
     LYRGNCRPIR FEPPMLDFHE QPVGMPKMEK VYLHNPSSEE TITLVSISAT TSHFHASFFQ
     NRKILPGGNT SFDVVFLARV VGNVENTLFI NTSNHGVFTY QVFGVGVPNP YRLRPFLGAR
     VPVNSSFSPI INIHNPHSEP LQVVEMYSSG GDLHLELPTG QQGGTRKLWE IPPYETKGVM
     RASFSSREAD NHTAFIRIKT NASDSTEFII LPVEVEVTTA PGIYSSTEML DFGTLRTQDL
     PKVLNLHLLN SGTKDVPITH RRQKSHLSFL GK
//