ID   H3BVI1_HUMAN            Unreviewed;        89 AA.
AC   H3BVI1;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   16-JAN-2019, entry version 60.
DE   SubName: Full=Protein disulfide-isomerase TMX3 {ECO:0000313|Ensembl:ENSP00000458132};
GN   Name=TMX3 {ECO:0000313|Ensembl:ENSP00000458132};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000458132, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000458132, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16177791; DOI=10.1038/nature03983;
RA   Nusbaum C., Zody M.C., Borowsky M.L., Kamal M., Kodira C.D.,
RA   Taylor T.D., Whittaker C.A., Chang J.L., Cuomo C.A., Dewar K.,
RA   FitzGerald M.G., Yang X., Abouelleil A., Allen N.R., Anderson S.,
RA   Bloom T., Bugalter B., Butler J., Cook A., DeCaprio D., Engels R.,
RA   Garber M., Gnirke A., Hafez N., Hall J.L., Norman C.H., Itoh T.,
RA   Jaffe D.B., Kuroki Y., Lehoczky J., Lui A., Macdonald P., Mauceli E.,
RA   Mikkelsen T.S., Naylor J.W., Nicol R., Nguyen C., Noguchi H.,
RA   O'Leary S.B., O'Neill K., Piqani B., Smith C.L., Talamas J.A.,
RA   Topham K., Totoki Y., Toyoda A., Wain H.M., Young S.K., Zeng Q.,
RA   Zimmer A.R., Fujiyama A., Hattori M., Birren B.W., Sakaki Y.,
RA   Lander E.S.;
RT   "DNA sequence and analysis of human chromosome 18.";
RL   Nature 437:551-555(2005).
RN   [2] {ECO:0000313|Ensembl:ENSP00000458132}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
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DR   EMBL; AC040896; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   SMR; H3BVI1; -.
DR   jPOST; H3BVI1; -.
DR   MaxQB; H3BVI1; -.
DR   PeptideAtlas; H3BVI1; -.
DR   PRIDE; H3BVI1; -.
DR   Ensembl; ENST00000564631; ENSP00000456587; ENSG00000166479.
DR   Ensembl; ENST00000569053; ENSP00000458132; ENSG00000166479.
DR   UCSC; uc060pxw.1; human.
DR   EuPathDB; HostDB:ENSG00000166479.9; -.
DR   HGNC; HGNC:24718; TMX3.
DR   OpenTargets; ENSG00000166479; -.
DR   eggNOG; KOG4277; Eukaryota.
DR   eggNOG; COG0526; LUCA.
DR   GeneTree; ENSGT00930000151022; -.
DR   ChiTaRS; TMX3; human.
DR   Proteomes; UP000005640; Chromosome 18.
DR   Bgee; ENSG00000166479; Expressed in 206 organ(s), highest expression level in frontal cortex.
DR   ExpressionAtlas; H3BVI1; baseline and differential.
DR   GO; GO:0005623; C:cell; IEA:GOC.
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   InterPro; IPR017937; Thioredoxin_CS.
DR   InterPro; IPR013766; Thioredoxin_domain.
DR   Pfam; PF00085; Thioredoxin; 1.
DR   SUPFAM; SSF52833; SSF52833; 1.
DR   PROSITE; PS00194; THIOREDOXIN_1; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|EPD:H3BVI1,
KW   ECO:0000213|MaxQB:H3BVI1, ECO:0000213|PeptideAtlas:H3BVI1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     26       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        27     89       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5014093596.
FT   DOMAIN       32     87       Thioredoxin. {ECO:0000259|Pfam:PF00085}.
SQ   SEQUENCE   89 AA;  10118 MW;  395B0F82341DC899 CRC64;
     MAAWKSWTAL RLCATVVVLD MVVCKGFVED LDESFKENRN DDIWLVDFYA PWCGHCKKLE
     PIWNEVGLEM KSIGSPVKVG KMDATSYSN
//