ID   H3BUV8_HUMAN            Unreviewed;       431 AA.
AC   H3BUV8;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   16-JAN-2019, entry version 40.
DE   SubName: Full=Lysyl oxidase homolog 1 {ECO:0000313|Ensembl:ENSP00000457827};
GN   Name=LOXL1 {ECO:0000313|Ensembl:ENSP00000457827};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000457827, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000457827, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16572171; DOI=10.1038/nature04601;
RA   Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K.,
RA   Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K.,
RA   FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N.,
RA   Abouelleil A., Arachchi H.M., Baradarani L., Birditt B., Bloom S.,
RA   Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K.,
RA   DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R.,
RA   Fahey J., Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G.,
RA   Johnson E., Jones C., Kamat A., Kaur A., Locke D.P., Madan A.,
RA   Munson G., Jaffe D.B., Lui A., Macdonald P., Mauceli E., Naylor J.W.,
RA   Nesbitt R., Nicol R., O'Leary S.B., Ratcliffe A., Rounsley S., She X.,
RA   Sneddon K.M., Stewart S., Sougnez C., Stone S.M., Topham K.,
RA   Vincent D., Wang S., Zimmer A.R., Birren B.W., Hood L., Lander E.S.,
RA   Nusbaum C.;
RT   "Analysis of the DNA sequence and duplication history of human
RT   chromosome 15.";
RL   Nature 440:671-675(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000457827}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
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DR   EMBL; AC108137; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; H3BUV8; -.
DR   jPOST; H3BUV8; -.
DR   PeptideAtlas; H3BUV8; -.
DR   PRIDE; H3BUV8; -.
DR   Ensembl; ENST00000566011; ENSP00000457827; ENSG00000129038.
DR   UCSC; uc059lfn.1; human.
DR   EuPathDB; HostDB:ENSG00000129038.15; -.
DR   HGNC; HGNC:6665; LOXL1.
DR   OpenTargets; ENSG00000129038; -.
DR   eggNOG; ENOG410IHTH; Eukaryota.
DR   eggNOG; ENOG41101E4; LUCA.
DR   GeneTree; ENSGT00940000161080; -.
DR   ChiTaRS; LOXL1; human.
DR   Proteomes; UP000005640; Chromosome 15.
DR   Bgee; ENSG00000129038; Expressed in 189 organ(s), highest expression level in pigmented layer of retina.
DR   ExpressionAtlas; H3BUV8; baseline and differential.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:H3BUV8,
KW   ECO:0000213|PeptideAtlas:H3BUV8};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     25       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        26    431       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003580702.
SQ   SEQUENCE   431 AA;  46076 MW;  BB314EB543C43469 CRC64;
     MALARGSRQL GALVWGACLC VLVHGQQAQP GQGSDPARWR QLIQWENNGQ VYSLLNSGSE
     YVPAGPQRSE SSSRVLLAGA PQAQQRRSHG SPRRRQAPSL PLPGRVGSDT VRGQARHPFG
     FGQVPDNWRE VAVGDSTGMA RARTSVSQQR HGGSASSVSA SAFASTYRQQ PSYPQQFPYP
     QAPFVSQYEN YDPASRTYDQ GFVYYRPAGG GVGAGAAAVA SAGVIYPYQP RARYEEYGGG
     EELPEYPPQG FYPAPERPYV PPPPPPPDGL DRRYSHSLYS EGTPGFEQAY PDPGPEAAQA
     HGGDPRLGWY PPYANPPPEA YGPPRALEPP YLPVRSSDTP PPGGERNGAQ QGRLSVGSVY
     RPNQNGRVTP AQTPACPGRK VEGQEQDGQA PGSGTSWGTR DHKDGGSLQT SPGRLTPGLA
     GERARASLRS P
//