ID   H3BUU2_HUMAN            Unreviewed;        80 AA.
AC   H3BUU2;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   05-DEC-2018, entry version 30.
DE   SubName: Full=Serine/threonine-protein kinase/endoribonuclease IRE2 {ECO:0000313|Ensembl:ENSP00000457796};
GN   Name=ERN2 {ECO:0000313|Ensembl:ENSP00000457796};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000457796, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000457796, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15616553; DOI=10.1038/nature03187;
RA   Martin J., Han C., Gordon L.A., Terry A., Prabhakar S., She X.,
RA   Xie G., Hellsten U., Chan Y.M., Altherr M., Couronne O., Aerts A.,
RA   Bajorek E., Black S., Blumer H., Branscomb E., Brown N.C., Bruno W.J.,
RA   Buckingham J.M., Callen D.F., Campbell C.S., Campbell M.L.,
RA   Campbell E.W., Caoile C., Challacombe J.F., Chasteen L.A.,
RA   Chertkov O., Chi H.C., Christensen M., Clark L.M., Cohn J.D.,
RA   Denys M., Detter J.C., Dickson M., Dimitrijevic-Bussod M., Escobar J.,
RA   Fawcett J.J., Flowers D., Fotopulos D., Glavina T., Gomez M.,
RA   Gonzales E., Goodstein D., Goodwin L.A., Grady D.L., Grigoriev I.,
RA   Groza M., Hammon N., Hawkins T., Haydu L., Hildebrand C.E., Huang W.,
RA   Israni S., Jett J., Jewett P.B., Kadner K., Kimball H., Kobayashi A.,
RA   Krawczyk M.-C., Leyba T., Longmire J.L., Lopez F., Lou Y., Lowry S.,
RA   Ludeman T., Manohar C.F., Mark G.A., McMurray K.L., Meincke L.J.,
RA   Morgan J., Moyzis R.K., Mundt M.O., Munk A.C., Nandkeshwar R.D.,
RA   Pitluck S., Pollard M., Predki P., Parson-Quintana B., Ramirez L.,
RA   Rash S., Retterer J., Ricke D.O., Robinson D.L., Rodriguez A.,
RA   Salamov A., Saunders E.H., Scott D., Shough T., Stallings R.L.,
RA   Stalvey M., Sutherland R.D., Tapia R., Tesmer J.G., Thayer N.,
RA   Thompson L.S., Tice H., Torney D.C., Tran-Gyamfi M., Tsai M.,
RA   Ulanovsky L.E., Ustaszewska A., Vo N., White P.S., Williams A.L.,
RA   Wills P.L., Wu J.-R., Wu K., Yang J., DeJong P., Bruce D.,
RA   Doggett N.A., Deaven L., Schmutz J., Grimwood J., Richardson P.,
RA   Rokhsar D.S., Eichler E.E., Gilna P., Lucas S.M., Myers R.M.,
RA   Rubin E.M., Pennacchio L.A.;
RT   "The sequence and analysis of duplication-rich human chromosome 16.";
RL   Nature 432:988-994(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000457796}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
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DR   EMBL; AC008870; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC012317; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KC877598; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KC877599; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   PRIDE; H3BUU2; -.
DR   Ensembl; ENST00000569903; ENSP00000457796; ENSG00000134398.
DR   UCSC; uc059see.1; human.
DR   EuPathDB; HostDB:ENSG00000134398.13; -.
DR   HGNC; HGNC:16942; ERN2.
DR   OpenTargets; ENSG00000134398; -.
DR   eggNOG; KOG1027; Eukaryota.
DR   eggNOG; COG0515; LUCA.
DR   GeneTree; ENSGT00940000160812; -.
DR   ChiTaRS; ERN2; human.
DR   Proteomes; UP000005640; Chromosome 16.
DR   Bgee; ENSG00000134398; Expressed in 210 organ(s), highest expression level in nasal cavity epithelium.
DR   ExpressionAtlas; H3BUU2; baseline and differential.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     36       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        37     80       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003581590.
SQ   SEQUENCE   80 AA;  8890 MW;  5D74760A64E79652 CRC64;
     MASAVRGSRP WPRLGLQLQF AALLLGTLSP QGCGWATRML GLLLGAQPHP VCSRRDWSRF
     ILSGQRTSCW CPPWMEVSTH
//