ID   H3BT53_HUMAN            Unreviewed;        63 AA.
AC   H3BT53;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   16-JAN-2019, entry version 36.
DE   SubName: Full=Fanconi anemia group A protein {ECO:0000313|Ensembl:ENSP00000457027};
DE   Flags: Fragment;
GN   Name=FANCA {ECO:0000313|Ensembl:ENSP00000457027};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000457027, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000457027, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15616553; DOI=10.1038/nature03187;
RA   Martin J., Han C., Gordon L.A., Terry A., Prabhakar S., She X.,
RA   Xie G., Hellsten U., Chan Y.M., Altherr M., Couronne O., Aerts A.,
RA   Bajorek E., Black S., Blumer H., Branscomb E., Brown N.C., Bruno W.J.,
RA   Buckingham J.M., Callen D.F., Campbell C.S., Campbell M.L.,
RA   Campbell E.W., Caoile C., Challacombe J.F., Chasteen L.A.,
RA   Chertkov O., Chi H.C., Christensen M., Clark L.M., Cohn J.D.,
RA   Denys M., Detter J.C., Dickson M., Dimitrijevic-Bussod M., Escobar J.,
RA   Fawcett J.J., Flowers D., Fotopulos D., Glavina T., Gomez M.,
RA   Gonzales E., Goodstein D., Goodwin L.A., Grady D.L., Grigoriev I.,
RA   Groza M., Hammon N., Hawkins T., Haydu L., Hildebrand C.E., Huang W.,
RA   Israni S., Jett J., Jewett P.B., Kadner K., Kimball H., Kobayashi A.,
RA   Krawczyk M.-C., Leyba T., Longmire J.L., Lopez F., Lou Y., Lowry S.,
RA   Ludeman T., Manohar C.F., Mark G.A., McMurray K.L., Meincke L.J.,
RA   Morgan J., Moyzis R.K., Mundt M.O., Munk A.C., Nandkeshwar R.D.,
RA   Pitluck S., Pollard M., Predki P., Parson-Quintana B., Ramirez L.,
RA   Rash S., Retterer J., Ricke D.O., Robinson D.L., Rodriguez A.,
RA   Salamov A., Saunders E.H., Scott D., Shough T., Stallings R.L.,
RA   Stalvey M., Sutherland R.D., Tapia R., Tesmer J.G., Thayer N.,
RA   Thompson L.S., Tice H., Torney D.C., Tran-Gyamfi M., Tsai M.,
RA   Ulanovsky L.E., Ustaszewska A., Vo N., White P.S., Williams A.L.,
RA   Wills P.L., Wu J.-R., Wu K., Yang J., DeJong P., Bruce D.,
RA   Doggett N.A., Deaven L., Schmutz J., Grimwood J., Richardson P.,
RA   Rokhsar D.S., Eichler E.E., Gilna P., Lucas S.M., Myers R.M.,
RA   Rubin E.M., Pennacchio L.A.;
RT   "The sequence and analysis of duplication-rich human chromosome 16.";
RL   Nature 432:988-994(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000457027}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
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DR   EMBL; AC005360; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC005567; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC092385; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF456225; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   jPOST; H3BT53; -.
DR   MaxQB; H3BT53; -.
DR   PeptideAtlas; H3BT53; -.
DR   PRIDE; H3BT53; -.
DR   Ensembl; ENST00000567205; ENSP00000457027; ENSG00000187741.
DR   UCSC; uc059ysh.1; human.
DR   EuPathDB; HostDB:ENSG00000187741.14; -.
DR   HGNC; HGNC:3582; FANCA.
DR   OpenTargets; ENSG00000187741; -.
DR   eggNOG; ENOG410IFHR; Eukaryota.
DR   eggNOG; ENOG411030W; LUCA.
DR   GeneTree; ENSGT00390000007852; -.
DR   ChiTaRS; FANCA; human.
DR   Proteomes; UP000005640; Chromosome 16.
DR   Bgee; ENSG00000187741; Expressed in 128 organ(s), highest expression level in right testis.
DR   ExpressionAtlas; H3BT53; baseline and differential.
DR   GO; GO:0043240; C:Fanconi anaemia nuclear complex; IEA:InterPro.
DR   GO; GO:0036297; P:interstrand cross-link repair; IEA:InterPro.
DR   InterPro; IPR003516; FANCA.
DR   PANTHER; PTHR12047; PTHR12047; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:H3BT53,
KW   ECO:0000213|PeptideAtlas:H3BT53};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     22       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        23     63       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003581561.
FT   NON_TER       1      1       {ECO:0000313|Ensembl:ENSP00000457027}.
SQ   SEQUENCE   63 AA;  6406 MW;  8C3DFCED222FB3D6 CRC64;
     GPSLSAPHVL GLAALAVHLG ESRSALPEVD VGPPAPGAGL PVPALFDSLL TCRTRDSLFF
     CLK
//