ID   H3BRP9_HUMAN            Unreviewed;       156 AA.
AC   H3BRP9;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   16-JAN-2019, entry version 38.
DE   SubName: Full=Signal-regulatory protein beta-1 {ECO:0000313|Ensembl:ENSP00000456351};
DE   Flags: Fragment;
GN   Name=SIRPB1 {ECO:0000313|Ensembl:ENSP00000456351};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000456351, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000456351, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=11780052; DOI=10.1038/414865a;
RA   Deloukas P., Matthews L.H., Ashurst J.L., Burton J., Gilbert J.G.R.,
RA   Jones M., Stavrides G., Almeida J.P., Babbage A.K., Bagguley C.L.,
RA   Bailey J., Barlow K.F., Bates K.N., Beard L.M., Beare D.M.,
RA   Beasley O.P., Bird C.P., Blakey S.E., Bridgeman A.M., Brown A.J.,
RA   Buck D., Burrill W.D., Butler A.P., Carder C., Carter N.P.,
RA   Chapman J.C., Clamp M., Clark G., Clark L.N., Clark S.Y., Clee C.M.,
RA   Clegg S., Cobley V.E., Collier R.E., Connor R.E., Corby N.R.,
RA   Coulson A., Coville G.J., Deadman R., Dhami P.D., Dunn M.,
RA   Ellington A.G., Frankland J.A., Fraser A., French L., Garner P.,
RA   Grafham D.V., Griffiths C., Griffiths M.N.D., Gwilliam R., Hall R.E.,
RA   Hammond S., Harley J.L., Heath P.D., Ho S., Holden J.L., Howden P.J.,
RA   Huckle E., Hunt A.R., Hunt S.E., Jekosch K., Johnson C.M., Johnson D.,
RA   Kay M.P., Kimberley A.M., King A., Knights A., Laird G.K., Lawlor S.,
RA   Lehvaeslaiho M.H., Leversha M.A., Lloyd C., Lloyd D.M., Lovell J.D.,
RA   Marsh V.L., Martin S.L., McConnachie L.J., McLay K., McMurray A.A.,
RA   Milne S.A., Mistry D., Moore M.J.F., Mullikin J.C., Nickerson T.,
RA   Oliver K., Parker A., Patel R., Pearce T.A.V., Peck A.I.,
RA   Phillimore B.J.C.T., Prathalingam S.R., Plumb R.W., Ramsay H.,
RA   Rice C.M., Ross M.T., Scott C.E., Sehra H.K., Shownkeen R., Sims S.,
RA   Skuce C.D., Smith M.L., Soderlund C., Steward C.A., Sulston J.E.,
RA   Swann R.M., Sycamore N., Taylor R., Tee L., Thomas D.W., Thorpe A.,
RA   Tracey A., Tromans A.C., Vaudin M., Wall M., Wallis J.M.,
RA   Whitehead S.L., Whittaker P., Willey D.L., Williams L., Williams S.A.,
RA   Wilming L., Wray P.W., Hubbard T., Durbin R.M., Bentley D.R., Beck S.,
RA   Rogers J.;
RT   "The DNA sequence and comparative analysis of human chromosome 20.";
RL   Nature 414:865-871(2001).
RN   [2] {ECO:0000313|Ensembl:ENSP00000456351}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
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DR   EMBL; AL049634; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AL138804; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AL592544; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; H3BRP9; -.
DR   jPOST; H3BRP9; -.
DR   MaxQB; H3BRP9; -.
DR   PeptideAtlas; H3BRP9; -.
DR   PRIDE; H3BRP9; -.
DR   Ensembl; ENST00000563840; ENSP00000456351; ENSG00000101307.
DR   UCSC; uc061uzf.1; human.
DR   EuPathDB; HostDB:ENSG00000101307.15; -.
DR   HGNC; HGNC:15928; SIRPB1.
DR   OpenTargets; ENSG00000101307; -.
DR   eggNOG; ENOG410J9BU; Eukaryota.
DR   eggNOG; ENOG410ZT4H; LUCA.
DR   GeneTree; ENSGT00940000163660; -.
DR   Proteomes; UP000005640; Chromosome 20.
DR   Bgee; ENSG00000101307; Expressed in 113 organ(s), highest expression level in blood.
DR   ExpressionAtlas; H3BRP9; baseline and differential.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR013106; Ig_V-set.
DR   Pfam; PF07686; V-set; 1.
DR   SMART; SM00409; IG; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     28       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        29    156       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003580654.
FT   DOMAIN       13    119       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   NON_TER     156    156       {ECO:0000313|Ensembl:ENSP00000456351}.
SQ   SEQUENCE   156 AA;  16611 MW;  642A82C12CFC3897 CRC64;
     MPVPASWPHP PCPFLLLTLL LGLTGVAGED ELQVIQPEKS VSVAAGESAT LRCAMTSLIP
     VGPIMWFRGA GAGRELIYNQ KEGHFPRVTT VSELTKRNNL DFSISISNIT PADAGTYYCV
     KFRKGSPDDV EFKSGAGTEL SVREAALAPT APLLVA
//