ID   H3BR90_HUMAN            Unreviewed;       332 AA.
AC   H3BR90;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 8.
DT   16-JAN-2019, entry version 41.
DE   SubName: Full=Mesothelin {ECO:0000313|Ensembl:ENSP00000456132};
DE   Flags: Fragment;
GN   Name=MSLN {ECO:0000313|Ensembl:ENSP00000456132};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000456132, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000456132, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15616553; DOI=10.1038/nature03187;
RA   Martin J., Han C., Gordon L.A., Terry A., Prabhakar S., She X.,
RA   Xie G., Hellsten U., Chan Y.M., Altherr M., Couronne O., Aerts A.,
RA   Bajorek E., Black S., Blumer H., Branscomb E., Brown N.C., Bruno W.J.,
RA   Buckingham J.M., Callen D.F., Campbell C.S., Campbell M.L.,
RA   Campbell E.W., Caoile C., Challacombe J.F., Chasteen L.A.,
RA   Chertkov O., Chi H.C., Christensen M., Clark L.M., Cohn J.D.,
RA   Denys M., Detter J.C., Dickson M., Dimitrijevic-Bussod M., Escobar J.,
RA   Fawcett J.J., Flowers D., Fotopulos D., Glavina T., Gomez M.,
RA   Gonzales E., Goodstein D., Goodwin L.A., Grady D.L., Grigoriev I.,
RA   Groza M., Hammon N., Hawkins T., Haydu L., Hildebrand C.E., Huang W.,
RA   Israni S., Jett J., Jewett P.B., Kadner K., Kimball H., Kobayashi A.,
RA   Krawczyk M.-C., Leyba T., Longmire J.L., Lopez F., Lou Y., Lowry S.,
RA   Ludeman T., Manohar C.F., Mark G.A., McMurray K.L., Meincke L.J.,
RA   Morgan J., Moyzis R.K., Mundt M.O., Munk A.C., Nandkeshwar R.D.,
RA   Pitluck S., Pollard M., Predki P., Parson-Quintana B., Ramirez L.,
RA   Rash S., Retterer J., Ricke D.O., Robinson D.L., Rodriguez A.,
RA   Salamov A., Saunders E.H., Scott D., Shough T., Stallings R.L.,
RA   Stalvey M., Sutherland R.D., Tapia R., Tesmer J.G., Thayer N.,
RA   Thompson L.S., Tice H., Torney D.C., Tran-Gyamfi M., Tsai M.,
RA   Ulanovsky L.E., Ustaszewska A., Vo N., White P.S., Williams A.L.,
RA   Wills P.L., Wu J.-R., Wu K., Yang J., DeJong P., Bruce D.,
RA   Doggett N.A., Deaven L., Schmutz J., Grimwood J., Richardson P.,
RA   Rokhsar D.S., Eichler E.E., Gilna P., Lucas S.M., Myers R.M.,
RA   Rubin E.M., Pennacchio L.A.;
RT   "The sequence and analysis of duplication-rich human chromosome 16.";
RL   Nature 432:988-994(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000456132}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
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DR   EMBL; AL031258; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   jPOST; H3BR90; -.
DR   PeptideAtlas; H3BR90; -.
DR   PRIDE; H3BR90; -.
DR   Ensembl; ENST00000563651; ENSP00000456132; ENSG00000102854.
DR   UCSC; uc059orv.1; human.
DR   EuPathDB; HostDB:ENSG00000102854.14; -.
DR   HGNC; HGNC:7371; MSLN.
DR   OpenTargets; ENSG00000102854; -.
DR   GeneTree; ENSGT00530000064019; -.
DR   ChiTaRS; MSLN; human.
DR   Proteomes; UP000005640; Chromosome 16.
DR   Bgee; ENSG00000102854; Expressed in 120 organ(s), highest expression level in right uterine tube.
DR   ExpressionAtlas; H3BR90; baseline and differential.
DR   InterPro; IPR010335; Mesothelin.
DR   InterPro; IPR026664; Stereocilin-rel.
DR   PANTHER; PTHR23412; PTHR23412; 2.
DR   Pfam; PF06060; Mesothelin; 2.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:H3BR90,
KW   ECO:0000213|PeptideAtlas:H3BR90};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     33       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        34    332       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5008415151.
FT   NON_TER     332    332       {ECO:0000313|Ensembl:ENSP00000456132}.
SQ   SEQUENCE   332 AA;  36729 MW;  97756C0330B28775 CRC64;
     MALPTARPLL GSCGTPALGS LLFLLFSLGW VQPSRTLAGE TGQEAAPLDG VLANPPNISS
     LSPRQLLGFP CAEVSGLSTE RVRELAVALA QKNVKLSTEQ LRCLAHRLSE PPEDLDALPL
     DLLLFLNPDA FSGPQACTRF FSRITKANVD LLPRGAPERQ RLLPAALACW GVRGSLLSEA
     DVRALGGLAC DLPGRFVAES AEVLLPRLGI VAAWRQRSSR DPSWRQPERT ILRPRFRREV
     EKTACPSGKK AREIDESLIF YKKWELEACV DAALLATQMD RVNAIPFTYE QLDVLKHKLD
     ELYPQGYPES VIQHLGYLFL KMSPEDIRKW NV
//