ID   LY6L_HUMAN              Reviewed;         138 AA.
AC   H3BQJ8;
DT   02-NOV-2016, integrated into UniProtKB/Swiss-Prot.
DT   18-APR-2012, sequence version 1.
DT   16-JAN-2019, entry version 47.
DE   RecName: Full=Lymphocyte antigen 6L {ECO:0000305};
DE   AltName: Full=Lymphocyte antigen 6 complex locus protein L {ECO:0000312|HGNC:HGNC:52284};
DE   Flags: Precursor;
GN   Name=LY6L {ECO:0000312|HGNC:HGNC:52284};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16421571; DOI=10.1038/nature04406;
RA   Nusbaum C., Mikkelsen T.S., Zody M.C., Asakawa S., Taudien S.,
RA   Garber M., Kodira C.D., Schueler M.G., Shimizu A., Whittaker C.A.,
RA   Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Yang X.,
RA   Allen N.R., Anderson S., Asakawa T., Blechschmidt K., Bloom T.,
RA   Borowsky M.L., Butler J., Cook A., Corum B., DeArellano K.,
RA   DeCaprio D., Dooley K.T., Dorris L. III, Engels R., Gloeckner G.,
RA   Hafez N., Hagopian D.S., Hall J.L., Ishikawa S.K., Jaffe D.B.,
RA   Kamat A., Kudoh J., Lehmann R., Lokitsang T., Macdonald P.,
RA   Major J.E., Matthews C.D., Mauceli E., Menzel U., Mihalev A.H.,
RA   Minoshima S., Murayama Y., Naylor J.W., Nicol R., Nguyen C.,
RA   O'Leary S.B., O'Neill K., Parker S.C.J., Polley A., Raymond C.K.,
RA   Reichwald K., Rodriguez J., Sasaki T., Schilhabel M., Siddiqui R.,
RA   Smith C.L., Sneddon T.P., Talamas J.A., Tenzin P., Topham K.,
RA   Venkataraman V., Wen G., Yamazaki S., Young S.K., Zeng Q.,
RA   Zimmer A.R., Rosenthal A., Birren B.W., Platzer M., Shimizu N.,
RA   Lander E.S.;
RT   "DNA sequence and analysis of human chromosome 8.";
RL   Nature 439:331-335(2006).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255}; Lipid-anchor,
CC       GPI-anchor {ECO:0000255}.
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DR   EMBL; AC083982; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC236721; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_016869619.1; XM_017014130.1.
DR   RefSeq; XP_016885686.1; XM_017030197.1.
DR   RefSeq; XP_016885962.1; XM_017030473.1.
DR   ProteinModelPortal; H3BQJ8; -.
DR   BioMuta; LY6L; -.
DR   PaxDb; H3BQJ8; -.
DR   PRIDE; H3BQJ8; -.
DR   Ensembl; ENST00000562505; ENSP00000455811; ENSG00000261667.
DR   Ensembl; ENST00000631950; ENSP00000487842; ENSG00000282693.
DR   GeneID; 101928108; -.
DR   KEGG; hsa:101928108; -.
DR   UCSC; uc064qwu.1; human.
DR   CTD; 101928108; -.
DR   EuPathDB; HostDB:ENSG00000261667.1; -.
DR   GeneCards; LY6L; -.
DR   HGNC; HGNC:52284; LY6L.
DR   neXtProt; NX_H3BQJ8; -.
DR   eggNOG; ENOG410JG9U; Eukaryota.
DR   eggNOG; ENOG41115ED; LUCA.
DR   GeneTree; ENSGT00940000154560; -.
DR   InParanoid; H3BQJ8; -.
DR   OMA; CYQCFKV; -.
DR   OrthoDB; 1592016at2759; -.
DR   PRO; PR:H3BQJ8; -.
DR   Proteomes; UP000005640; Chromosome 8.
DR   Bgee; ENSG00000261667; Expressed in 12 organ(s), highest expression level in testis.
DR   GO; GO:0031225; C:anchored component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR016054; LY6_UPA_recep-like.
DR   Pfam; PF00021; UPAR_LY6; 1.
DR   SMART; SM00134; LU; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Complete proteome; Disulfide bond; Glycoprotein;
KW   GPI-anchor; Lipoprotein; Membrane; Reference proteome; Signal.
FT   SIGNAL        1     16       {ECO:0000255}.
FT   CHAIN        17    117       Lymphocyte antigen 6L. {ECO:0000305}.
FT                                /FTId=PRO_5008163148.
FT   PROPEP      118    138       Removed in mature form. {ECO:0000305}.
FT                                /FTId=PRO_0000438094.
FT   DOMAIN       28    122       UPAR/Ly6. {ECO:0000255}.
FT   LIPID       117    117       GPI-anchor amidated glycine.
FT                                {ECO:0000255}.
FT   CARBOHYD     27     27       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
FT   DISULFID     30     47       {ECO:0000250|UniProtKB:Q03405}.
FT   DISULFID    103    108       {ECO:0000250|UniProtKB:Q03405}.
SQ   SEQUENCE   138 AA;  15317 MW;  6CFCA3A34C01248C CRC64;
     MERLVLTLCT LPLAVASAGC ATTPARNLSC YQCFKVSSWT ECPPTWCSPL DQVCISNEVV
     VSFKWSVRVL LSKRCAPRCP NDNMKFEWSP APMVQGVITR RCCSWALCNR ALTPQEGRWA
     LRGGLLLQVG LSLLRALL
//