ID   H3BPK8_HUMAN            Unreviewed;       373 AA.
AC   H3BPK8;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   16-JAN-2019, entry version 40.
DE   SubName: Full=Putative sodium-coupled neutral amino acid transporter 7 {ECO:0000313|Ensembl:ENSP00000455362};
GN   Name=SLC38A7 {ECO:0000313|Ensembl:ENSP00000455362};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000455362, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000455362, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15616553; DOI=10.1038/nature03187;
RA   Martin J., Han C., Gordon L.A., Terry A., Prabhakar S., She X.,
RA   Xie G., Hellsten U., Chan Y.M., Altherr M., Couronne O., Aerts A.,
RA   Bajorek E., Black S., Blumer H., Branscomb E., Brown N.C., Bruno W.J.,
RA   Buckingham J.M., Callen D.F., Campbell C.S., Campbell M.L.,
RA   Campbell E.W., Caoile C., Challacombe J.F., Chasteen L.A.,
RA   Chertkov O., Chi H.C., Christensen M., Clark L.M., Cohn J.D.,
RA   Denys M., Detter J.C., Dickson M., Dimitrijevic-Bussod M., Escobar J.,
RA   Fawcett J.J., Flowers D., Fotopulos D., Glavina T., Gomez M.,
RA   Gonzales E., Goodstein D., Goodwin L.A., Grady D.L., Grigoriev I.,
RA   Groza M., Hammon N., Hawkins T., Haydu L., Hildebrand C.E., Huang W.,
RA   Israni S., Jett J., Jewett P.B., Kadner K., Kimball H., Kobayashi A.,
RA   Krawczyk M.-C., Leyba T., Longmire J.L., Lopez F., Lou Y., Lowry S.,
RA   Ludeman T., Manohar C.F., Mark G.A., McMurray K.L., Meincke L.J.,
RA   Morgan J., Moyzis R.K., Mundt M.O., Munk A.C., Nandkeshwar R.D.,
RA   Pitluck S., Pollard M., Predki P., Parson-Quintana B., Ramirez L.,
RA   Rash S., Retterer J., Ricke D.O., Robinson D.L., Rodriguez A.,
RA   Salamov A., Saunders E.H., Scott D., Shough T., Stallings R.L.,
RA   Stalvey M., Sutherland R.D., Tapia R., Tesmer J.G., Thayer N.,
RA   Thompson L.S., Tice H., Torney D.C., Tran-Gyamfi M., Tsai M.,
RA   Ulanovsky L.E., Ustaszewska A., Vo N., White P.S., Williams A.L.,
RA   Wills P.L., Wu J.-R., Wu K., Yang J., DeJong P., Bruce D.,
RA   Doggett N.A., Deaven L., Schmutz J., Grimwood J., Richardson P.,
RA   Rokhsar D.S., Eichler E.E., Gilna P., Lucas S.M., Myers R.M.,
RA   Rubin E.M., Pennacchio L.A.;
RT   "The sequence and analysis of duplication-rich human chromosome 16.";
RL   Nature 432:988-994(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000455362}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
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DR   EMBL; AC010287; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; H3BPK8; -.
DR   jPOST; H3BPK8; -.
DR   MaxQB; H3BPK8; -.
DR   PeptideAtlas; H3BPK8; -.
DR   PRIDE; H3BPK8; -.
DR   Ensembl; ENST00000564010; ENSP00000455362; ENSG00000103042.
DR   UCSC; uc010vil.2; human.
DR   EuPathDB; HostDB:ENSG00000103042.8; -.
DR   HGNC; HGNC:25582; SLC38A7.
DR   OpenTargets; ENSG00000103042; -.
DR   eggNOG; KOG1305; Eukaryota.
DR   eggNOG; COG0814; LUCA.
DR   GeneTree; ENSGT00940000158136; -.
DR   ChiTaRS; SLC38A7; human.
DR   Proteomes; UP000005640; Chromosome 16.
DR   Bgee; ENSG00000103042; Expressed in 193 organ(s), highest expression level in testis.
DR   ExpressionAtlas; H3BPK8; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR013057; AA_transpt_TM.
DR   Pfam; PF01490; Aa_trans; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Membrane {ECO:0000256|SAAS:SAAS00051336, ECO:0000256|SAM:Phobius};
KW   Proteomics identification {ECO:0000213|MaxQB:H3BPK8,
KW   ECO:0000213|PeptideAtlas:H3BPK8};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00051336,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00051336,
KW   ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     20       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        21    373       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003580982.
FT   TRANSMEM     44     62       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    113    135       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    155    176       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    188    213       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    233    254       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    282    299       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    305    326       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    338    359       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN        8    358       Aa_trans. {ECO:0000259|Pfam:PF01490}.
SQ   SEQUENCE   373 AA;  40898 MW;  2EE604BBC6E0FD8A CRC64;
     MGMLVFIISG LVILAYCSQA SNERTYQEVV WAVCGKLTGV LCEVAIAVYT FGTCIAFLII
     IGDQQDKIIA VMAKEPEGAS GPWYTDRKFT ISLTAFLFIL PLSIPREIGF QKYASFLSVV
     GTWYVTAIVI IKYIWPDKEM TPGNILTRPA SWMAVFNAMP TICFGFQCHV SSVPVFNSMQ
     QPEVKTWGGV VTAAMVIALA VYMGTGICGF LTFGAAVDPD VLLSYPSEDM AVAVARAFII
     LSVLTSYPIL HFCGRAVVEG LWLRYQGVPV EEDVGRERRR RVLQTLVWFL LTLLLALFIP
     DIGKVISVIG GLAACFIFVF PGLCLIQAKL SEMEEVKPAS WWVLVSYGVL LVTLGAFIFG
     QTTANAIFVD LLA
//