ID   H3BNY0_HUMAN            Unreviewed;       186 AA.
AC   H3BNY0;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   05-DEC-2018, entry version 43.
DE   SubName: Full=Inactive serine protease 54 {ECO:0000313|Ensembl:ENSP00000455055};
DE   Flags: Fragment;
GN   Name=PRSS54 {ECO:0000313|Ensembl:ENSP00000455055};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000455055, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000455055, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15616553; DOI=10.1038/nature03187;
RA   Martin J., Han C., Gordon L.A., Terry A., Prabhakar S., She X.,
RA   Xie G., Hellsten U., Chan Y.M., Altherr M., Couronne O., Aerts A.,
RA   Bajorek E., Black S., Blumer H., Branscomb E., Brown N.C., Bruno W.J.,
RA   Buckingham J.M., Callen D.F., Campbell C.S., Campbell M.L.,
RA   Campbell E.W., Caoile C., Challacombe J.F., Chasteen L.A.,
RA   Chertkov O., Chi H.C., Christensen M., Clark L.M., Cohn J.D.,
RA   Denys M., Detter J.C., Dickson M., Dimitrijevic-Bussod M., Escobar J.,
RA   Fawcett J.J., Flowers D., Fotopulos D., Glavina T., Gomez M.,
RA   Gonzales E., Goodstein D., Goodwin L.A., Grady D.L., Grigoriev I.,
RA   Groza M., Hammon N., Hawkins T., Haydu L., Hildebrand C.E., Huang W.,
RA   Israni S., Jett J., Jewett P.B., Kadner K., Kimball H., Kobayashi A.,
RA   Krawczyk M.-C., Leyba T., Longmire J.L., Lopez F., Lou Y., Lowry S.,
RA   Ludeman T., Manohar C.F., Mark G.A., McMurray K.L., Meincke L.J.,
RA   Morgan J., Moyzis R.K., Mundt M.O., Munk A.C., Nandkeshwar R.D.,
RA   Pitluck S., Pollard M., Predki P., Parson-Quintana B., Ramirez L.,
RA   Rash S., Retterer J., Ricke D.O., Robinson D.L., Rodriguez A.,
RA   Salamov A., Saunders E.H., Scott D., Shough T., Stallings R.L.,
RA   Stalvey M., Sutherland R.D., Tapia R., Tesmer J.G., Thayer N.,
RA   Thompson L.S., Tice H., Torney D.C., Tran-Gyamfi M., Tsai M.,
RA   Ulanovsky L.E., Ustaszewska A., Vo N., White P.S., Williams A.L.,
RA   Wills P.L., Wu J.-R., Wu K., Yang J., DeJong P., Bruce D.,
RA   Doggett N.A., Deaven L., Schmutz J., Grimwood J., Richardson P.,
RA   Rokhsar D.S., Eichler E.E., Gilna P., Lucas S.M., Myers R.M.,
RA   Rubin E.M., Pennacchio L.A.;
RT   "The sequence and analysis of duplication-rich human chromosome 16.";
RL   Nature 432:988-994(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000455055}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
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DR   EMBL; AC009107; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; H3BNY0; -.
DR   SMR; H3BNY0; -.
DR   PeptideAtlas; H3BNY0; -.
DR   PRIDE; H3BNY0; -.
DR   Ensembl; ENST00000569727; ENSP00000455055; ENSG00000103023.
DR   UCSC; uc059vad.1; human.
DR   EuPathDB; HostDB:ENSG00000103023.11; -.
DR   HGNC; HGNC:26336; PRSS54.
DR   OpenTargets; ENSG00000103023; -.
DR   eggNOG; KOG3627; Eukaryota.
DR   eggNOG; COG5640; LUCA.
DR   GeneTree; ENSGT00940000153166; -.
DR   ChiTaRS; PRSS54; human.
DR   Proteomes; UP000005640; Chromosome 16.
DR   Bgee; ENSG00000103023; Expressed in 49 organ(s), highest expression level in testis.
DR   ExpressionAtlas; H3BNY0; baseline and differential.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   InterPro; IPR009003; Peptidase_S1_PA.
DR   InterPro; IPR001254; Trypsin_dom.
DR   Pfam; PF00089; Trypsin; 1.
DR   SUPFAM; SSF50494; SSF50494; 1.
DR   PROSITE; PS50240; TRYPSIN_DOM; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|PeptideAtlas:H3BNY0};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     30       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        31    186       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003580613.
FT   DOMAIN       37    186       Peptidase S1.
FT                                {ECO:0000259|PROSITE:PS50240}.
FT   NON_TER     186    186       {ECO:0000313|Ensembl:ENSP00000455055}.
SQ   SEQUENCE   186 AA;  20293 MW;  4BDA287534B2E62B CRC64;
     MVSAAGLSGD GKMRGVLLVL LGLLYSSTSC GVQKASVFYG PDPKEGLVSS MEFPWVVSLQ
     DSQYTHLAFG CILSEFWVLS IASAIQNRKD IVVIVGISNM DPSKIAHTEY PVNTIIIHED
     FDNNSMSNNI ALLKTDTAMH FGNLVQSICF LGRMLHTPPV LQNCWVSGWN PTSATGNHMT
     MSVLRK
//