ID   H3BMN3_HUMAN            Unreviewed;       125 AA.
AC   H3BMN3;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   05-DEC-2018, entry version 41.
DE   SubName: Full=Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000454465};
DE   Flags: Fragment;
GN   Name=LINGO1 {ECO:0000313|Ensembl:ENSP00000454465};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000454465, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000454465, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16572171; DOI=10.1038/nature04601;
RA   Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K.,
RA   Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K.,
RA   FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N.,
RA   Abouelleil A., Arachchi H.M., Baradarani L., Birditt B., Bloom S.,
RA   Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K.,
RA   DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R.,
RA   Fahey J., Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G.,
RA   Johnson E., Jones C., Kamat A., Kaur A., Locke D.P., Madan A.,
RA   Munson G., Jaffe D.B., Lui A., Macdonald P., Mauceli E., Naylor J.W.,
RA   Nesbitt R., Nicol R., O'Leary S.B., Ratcliffe A., Rounsley S., She X.,
RA   Sneddon K.M., Stewart S., Sougnez C., Stone S.M., Topham K.,
RA   Vincent D., Wang S., Zimmer A.R., Birren B.W., Hood L., Lander E.S.,
RA   Nusbaum C.;
RT   "Analysis of the DNA sequence and duplication history of human
RT   chromosome 15.";
RL   Nature 440:671-675(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000454465}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; AC046168; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC105133; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC110607; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; H3BMN3; -.
DR   PeptideAtlas; H3BMN3; -.
DR   PRIDE; H3BMN3; -.
DR   Ensembl; ENST00000567726; ENSP00000454465; ENSG00000169783.
DR   UCSC; uc059lzx.1; human.
DR   EuPathDB; HostDB:ENSG00000169783.12; -.
DR   HGNC; HGNC:21205; LINGO1.
DR   OpenTargets; ENSG00000169783; -.
DR   eggNOG; KOG0619; Eukaryota.
DR   eggNOG; COG4886; LUCA.
DR   GeneTree; ENSGT00940000154996; -.
DR   ChiTaRS; LINGO1; human.
DR   Proteomes; UP000005640; Chromosome 15.
DR   Bgee; ENSG00000169783; Expressed in 172 organ(s), highest expression level in temporal lobe.
DR   ExpressionAtlas; H3BMN3; baseline and differential.
DR   Gene3D; 3.80.10.10; -; 1.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR000372; LRRNT.
DR   Pfam; PF13855; LRR_8; 1.
DR   SMART; SM00013; LRRNT; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Leucine-rich repeat {ECO:0000256|SAAS:SAAS00138699};
KW   Proteomics identification {ECO:0000213|PeptideAtlas:H3BMN3};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     35       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        36    125       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003580226.
FT   DOMAIN       35     69       LRRNT. {ECO:0000259|SMART:SM00013}.
FT   NON_TER     125    125       {ECO:0000313|Ensembl:ENSP00000454465}.
SQ   SEQUENCE   125 AA;  13682 MW;  422FE899D472CE9F CRC64;
     MLAGGVRSMP SPLLACWQPI LLLVLGSVLS GSATGCPPRC ECSAQDRAVL CHRKRFVAVP
     EGIPTETRLL DLGKNRIKTL NQDEFASFPH LEELELNENI VSAVEPGAFN NLFNLRTLGL
     RSNRL
//