ID   H3BM69_HUMAN            Unreviewed;       114 AA.
AC   H3BM69;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   05-DEC-2018, entry version 47.
DE   SubName: Full=Immunoglobulin superfamily-containing leucine-rich repeat protein 2 {ECO:0000313|Ensembl:ENSP00000454259};
DE   Flags: Fragment;
GN   Name=ISLR2 {ECO:0000313|Ensembl:ENSP00000454259};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000454259, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000454259, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16572171; DOI=10.1038/nature04601;
RA   Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K.,
RA   Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K.,
RA   FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N.,
RA   Abouelleil A., Arachchi H.M., Baradarani L., Birditt B., Bloom S.,
RA   Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K.,
RA   DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R.,
RA   Fahey J., Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G.,
RA   Johnson E., Jones C., Kamat A., Kaur A., Locke D.P., Madan A.,
RA   Munson G., Jaffe D.B., Lui A., Macdonald P., Mauceli E., Naylor J.W.,
RA   Nesbitt R., Nicol R., O'Leary S.B., Ratcliffe A., Rounsley S., She X.,
RA   Sneddon K.M., Stewart S., Sougnez C., Stone S.M., Topham K.,
RA   Vincent D., Wang S., Zimmer A.R., Birren B.W., Hood L., Lander E.S.,
RA   Nusbaum C.;
RT   "Analysis of the DNA sequence and duplication history of human
RT   chromosome 15.";
RL   Nature 440:671-675(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000454259}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
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DR   EMBL; AC010931; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; H3BM69; -.
DR   PeptideAtlas; H3BM69; -.
DR   PRIDE; H3BM69; -.
DR   Ensembl; ENST00000565332; ENSP00000454259; ENSG00000167178.
DR   UCSC; uc059lgr.1; human.
DR   EuPathDB; HostDB:ENSG00000167178.15; -.
DR   HGNC; HGNC:29286; ISLR2.
DR   OpenTargets; ENSG00000167178; -.
DR   eggNOG; KOG0619; Eukaryota.
DR   eggNOG; COG4886; LUCA.
DR   GeneTree; ENSGT00940000162846; -.
DR   ChiTaRS; ISLR2; human.
DR   Proteomes; UP000005640; Chromosome 15.
DR   Bgee; ENSG00000167178; Expressed in 96 organ(s), highest expression level in forebrain.
DR   ExpressionAtlas; H3BM69; baseline and differential.
DR   Gene3D; 3.80.10.10; -; 1.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   Pfam; PF13855; LRR_8; 1.
DR   PROSITE; PS51450; LRR; 3.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|PeptideAtlas:H3BM69};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     18       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        19    114       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003580224.
FT   NON_TER     114    114       {ECO:0000313|Ensembl:ENSP00000454259}.
SQ   SEQUENCE   114 AA;  12484 MW;  E9E1B41674AC757A CRC64;
     MFPLRALWLV WALLGVAGSC PEPCACVDKY AHQFADCAYK ELREVPEGLP ANVTTLSLSA
     NKITVLRRGA FADVTQVTSL WLAHNEVRTV EPGALAVLSQ LKNLDLSHNF ISSF
//