ID   H0YN80_HUMAN            Unreviewed;        55 AA.
AC   H0YN80;
DT   22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT   22-FEB-2012, sequence version 1.
DT   05-DEC-2018, entry version 42.
DE   SubName: Full=Fibrillin-1 {ECO:0000313|Ensembl:ENSP00000453901};
GN   Name=FBN1 {ECO:0000313|Ensembl:ENSP00000453901};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000453901, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000453901, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16572171; DOI=10.1038/nature04601;
RA   Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K.,
RA   Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K.,
RA   FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N.,
RA   Abouelleil A., Arachchi H.M., Baradarani L., Birditt B., Bloom S.,
RA   Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K.,
RA   DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R.,
RA   Fahey J., Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G.,
RA   Johnson E., Jones C., Kamat A., Kaur A., Locke D.P., Madan A.,
RA   Munson G., Jaffe D.B., Lui A., Macdonald P., Mauceli E., Naylor J.W.,
RA   Nesbitt R., Nicol R., O'Leary S.B., Ratcliffe A., Rounsley S., She X.,
RA   Sneddon K.M., Stewart S., Sougnez C., Stone S.M., Topham K.,
RA   Vincent D., Wang S., Zimmer A.R., Birren B.W., Hood L., Lander E.S.,
RA   Nusbaum C.;
RT   "Analysis of the DNA sequence and duplication history of human
RT   chromosome 15.";
RL   Nature 440:671-675(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000453901}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JAN-2012) to UniProtKB.
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DR   EMBL; AC022467; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC084757; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC084758; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF459685; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   PeptideAtlas; H0YN80; -.
DR   Ensembl; ENST00000560355; ENSP00000453901; ENSG00000166147.
DR   UCSC; uc059iyp.1; human.
DR   EuPathDB; HostDB:ENSG00000166147.13; -.
DR   HGNC; HGNC:3603; FBN1.
DR   OpenTargets; ENSG00000166147; -.
DR   eggNOG; ENOG410IR7H; Eukaryota.
DR   eggNOG; ENOG410XSTY; LUCA.
DR   GeneTree; ENSGT00940000155011; -.
DR   ChiTaRS; FBN1; human.
DR   Proteomes; UP000005640; Chromosome 15.
DR   Bgee; ENSG00000166147; Expressed in 229 organ(s), highest expression level in adipose tissue of abdominal region.
DR   ExpressionAtlas; H0YN80; baseline and differential.
DR   GO; GO:0062023; C:collagen-containing extracellular matrix; IEA:InterPro.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005201; F:extracellular matrix structural constituent; IEA:InterPro.
DR   InterPro; IPR011398; FBN.
DR   PANTHER; PTHR24039; PTHR24039; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:H0YN80,
KW   ECO:0000213|PeptideAtlas:H0YN80};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     27       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        28     55       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003546074.
SQ   SEQUENCE   55 AA;  5808 MW;  00467349503B32FE CRC64;
     MRRGRLLEIA LGFTVLLASY TSHGADANLE AGNVKETRAS RAKRRGGGGH DALKG
//