ID   H0YMV8_HUMAN            Unreviewed;       100 AA.
AC   H0YMV8;
DT   22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT   22-FEB-2012, sequence version 1.
DT   13-FEB-2019, entry version 52.
DE   RecName: Full=40S ribosomal protein S27 {ECO:0000256|RuleBase:RU000671};
GN   Name=RPS27L {ECO:0000313|Ensembl:ENSP00000453764};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000453764, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000453764, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16572171; DOI=10.1038/nature04601;
RA   Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K.,
RA   Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K.,
RA   FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N.,
RA   Abouelleil A., Arachchi H.M., Baradarani L., Birditt B., Bloom S.,
RA   Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K.,
RA   DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R.,
RA   Fahey J., Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G.,
RA   Johnson E., Jones C., Kamat A., Kaur A., Locke D.P., Madan A.,
RA   Munson G., Jaffe D.B., Lui A., Macdonald P., Mauceli E., Naylor J.W.,
RA   Nesbitt R., Nicol R., O'Leary S.B., Ratcliffe A., Rounsley S., She X.,
RA   Sneddon K.M., Stewart S., Sougnez C., Stone S.M., Topham K.,
RA   Vincent D., Wang S., Zimmer A.R., Birren B.W., Hood L., Lander E.S.,
RA   Nusbaum C.;
RT   "Analysis of the DNA sequence and duplication history of human
RT   chromosome 15.";
RL   Nature 440:671-675(2006).
RN   [2] {ECO:0000213|PubMed:21269460}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA   Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P.,
RA   Burckstummer T., Bennett K.L., Superti-Furga G., Colinge J.;
RT   "Initial characterization of the human central proteome.";
RL   BMC Syst. Biol. 5:17-17(2011).
RN   [3] {ECO:0000313|Ensembl:ENSP00000453764}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JAN-2012) to UniProtKB.
RN   [4] {ECO:0000213|PubMed:24275569}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=24275569; DOI=10.1016/j.jprot.2013.11.014;
RA   Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D.,
RA   Wang L., Ye M., Zou H.;
RT   "An enzyme assisted RP-RPLC approach for in-depth analysis of human
RT   liver phosphoproteome.";
RL   J. Proteomics 96:253-262(2014).
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|RuleBase:RU000671};
CC       Note=Binds 1 zinc ion per subunit.
CC       {ECO:0000256|RuleBase:RU000671};
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eS27
CC       family. {ECO:0000256|RuleBase:RU000671}.
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DR   EMBL; AC087612; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; H0YMV8; -.
DR   SwissPalm; H0YMV8; -.
DR   EPD; H0YMV8; -.
DR   jPOST; H0YMV8; -.
DR   MaxQB; H0YMV8; -.
DR   PeptideAtlas; H0YMV8; -.
DR   PRIDE; H0YMV8; -.
DR   Ensembl; ENST00000462430; ENSP00000453764; ENSG00000185088.
DR   UCSC; uc059kbr.1; human.
DR   EuPathDB; HostDB:ENSG00000185088.13; -.
DR   HGNC; HGNC:18476; RPS27L.
DR   OpenTargets; ENSG00000185088; -.
DR   eggNOG; KOG1779; Eukaryota.
DR   eggNOG; COG2051; LUCA.
DR   GeneTree; ENSGT00940000153329; -.
DR   OMA; QSCGVIL; -.
DR   ChiTaRS; RPS27L; human.
DR   Proteomes; UP000005640; Chromosome 15.
DR   Bgee; ENSG00000185088; Expressed in 233 organ(s), highest expression level in prostate gland.
DR   ExpressionAtlas; H0YMV8; baseline and differential.
DR   GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
DR   HAMAP; MF_00371; Ribosomal_S27e; 1.
DR   InterPro; IPR000592; Ribosomal_S27e.
DR   InterPro; IPR011332; Ribosomal_zn-bd.
DR   PANTHER; PTHR11594; PTHR11594; 1.
DR   Pfam; PF01667; Ribosomal_S27e; 1.
DR   ProDom; PD004466; Ribosomal_S27e; 1.
DR   SUPFAM; SSF57829; SSF57829; 1.
DR   PROSITE; PS01168; RIBOSOMAL_S27E; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Metal-binding {ECO:0000256|RuleBase:RU000671};
KW   Proteomics identification {ECO:0000213|EPD:H0YMV8,
KW   ECO:0000213|MaxQB:H0YMV8, ECO:0000213|PeptideAtlas:H0YMV8};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Ribonucleoprotein {ECO:0000256|RuleBase:RU000671};
KW   Ribosomal protein {ECO:0000256|RuleBase:RU000671};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Zinc {ECO:0000256|RuleBase:RU000671};
KW   Zinc-finger {ECO:0000256|RuleBase:RU000671}.
FT   SIGNAL        1     22       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        23    100       40S ribosomal protein S27.
FT                                {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003546756.
SQ   SEQUENCE   100 AA;  11346 MW;  2683B4C7D06A2D4D CRC64;
     MCQRCGLKLI VIICFFVQLA RDLLHPSLEE EKKKHKKKRL VQSPNSYFMD VKCPGCYKIT
     TVFSHAQTVV LCVGCSTVLC QPTGGKARLT EGCSFRRKQH
//