ID   H0YMA6_HUMAN            Unreviewed;       148 AA.
AC   H0YMA6;
DT   22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT   22-FEB-2012, sequence version 1.
DT   05-DEC-2018, entry version 41.
DE   SubName: Full=Semaphorin-6D {ECO:0000313|Ensembl:ENSP00000453530};
DE   Flags: Fragment;
GN   Name=SEMA6D {ECO:0000313|Ensembl:ENSP00000453530};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000453530, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000453530, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16572171; DOI=10.1038/nature04601;
RA   Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K.,
RA   Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K.,
RA   FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N.,
RA   Abouelleil A., Arachchi H.M., Baradarani L., Birditt B., Bloom S.,
RA   Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K.,
RA   DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R.,
RA   Fahey J., Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G.,
RA   Johnson E., Jones C., Kamat A., Kaur A., Locke D.P., Madan A.,
RA   Munson G., Jaffe D.B., Lui A., Macdonald P., Mauceli E., Naylor J.W.,
RA   Nesbitt R., Nicol R., O'Leary S.B., Ratcliffe A., Rounsley S., She X.,
RA   Sneddon K.M., Stewart S., Sougnez C., Stone S.M., Topham K.,
RA   Vincent D., Wang S., Zimmer A.R., Birren B.W., Hood L., Lander E.S.,
RA   Nusbaum C.;
RT   "Analysis of the DNA sequence and duplication history of human
RT   chromosome 15.";
RL   Nature 440:671-675(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000453530}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JAN-2012) to UniProtKB.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00352}.
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DR   EMBL; AC009558; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC012050; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC023905; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC044787; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC066615; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC084882; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KC877554; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF456040; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; H0YMA6; -.
DR   PeptideAtlas; H0YMA6; -.
DR   PRIDE; H0YMA6; -.
DR   Ensembl; ENST00000561133; ENSP00000453530; ENSG00000137872.
DR   UCSC; uc059iwk.1; human.
DR   EuPathDB; HostDB:ENSG00000137872.15; -.
DR   HGNC; HGNC:16770; SEMA6D.
DR   OpenTargets; ENSG00000137872; -.
DR   eggNOG; KOG3611; Eukaryota.
DR   eggNOG; ENOG410XQZC; LUCA.
DR   GeneTree; ENSGT00940000159303; -.
DR   ChiTaRS; SEMA6D; human.
DR   Proteomes; UP000005640; Chromosome 15.
DR   Bgee; ENSG00000137872; Expressed in 199 organ(s), highest expression level in forebrain.
DR   ExpressionAtlas; H0YMA6; baseline and differential.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR001627; Semap_dom.
DR   InterPro; IPR036352; Semap_dom_sf.
DR   InterPro; IPR027231; Semaphorin.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   PANTHER; PTHR11036; PTHR11036; 1.
DR   Pfam; PF01403; Sema; 1.
DR   SUPFAM; SSF101912; SSF101912; 1.
DR   PROSITE; PS51004; SEMA; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|PeptideAtlas:H0YMA6};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     20       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        21    148       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003546220.
FT   DOMAIN       27    148       Sema. {ECO:0000259|PROSITE:PS51004}.
FT   NON_TER     148    148       {ECO:0000313|Ensembl:ENSP00000453530}.
SQ   SEQUENCE   148 AA;  17605 MW;  6C5C3F8DD93533AB CRC64;
     MRVFLLCAYI LLLMVSQLRA VSFPEDDEPL NTVDYHYSRQ YPVFRGRPSG NESQHRLDFQ
     LMLKIRDTLY IAGRDQVYTV NLNEMPKTEV IPNKKLTWRS RQQDRENCAM KGKHKDECHN
     FIKVFVPRND EMVFVCGTNA FNPMCRYY
//