ID   H0YLI4_HUMAN            Unreviewed;        80 AA.
AC   H0YLI4;
DT   22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT   22-FEB-2012, sequence version 1.
DT   16-JAN-2019, entry version 39.
DE   SubName: Full=LRP chaperone MESD {ECO:0000313|Ensembl:ENSP00000453220};
GN   Name=MESD {ECO:0000313|Ensembl:ENSP00000453220};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000453220, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000453220, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16572171; DOI=10.1038/nature04601;
RA   Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K.,
RA   Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K.,
RA   FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N.,
RA   Abouelleil A., Arachchi H.M., Baradarani L., Birditt B., Bloom S.,
RA   Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K.,
RA   DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R.,
RA   Fahey J., Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G.,
RA   Johnson E., Jones C., Kamat A., Kaur A., Locke D.P., Madan A.,
RA   Munson G., Jaffe D.B., Lui A., Macdonald P., Mauceli E., Naylor J.W.,
RA   Nesbitt R., Nicol R., O'Leary S.B., Ratcliffe A., Rounsley S., She X.,
RA   Sneddon K.M., Stewart S., Sougnez C., Stone S.M., Topham K.,
RA   Vincent D., Wang S., Zimmer A.R., Birren B.W., Hood L., Lander E.S.,
RA   Nusbaum C.;
RT   "Analysis of the DNA sequence and duplication history of human
RT   chromosome 15.";
RL   Nature 440:671-675(2006).
RN   [2] {ECO:0000213|PubMed:21269460}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA   Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P.,
RA   Burckstummer T., Bennett K.L., Superti-Furga G., Colinge J.;
RT   "Initial characterization of the human central proteome.";
RL   BMC Syst. Biol. 5:17-17(2011).
RN   [3] {ECO:0000313|Ensembl:ENSP00000453220}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JAN-2012) to UniProtKB.
RN   [4] {ECO:0000213|PubMed:25944712}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=25944712;
RA   Vaca Jacome A.S., Rabilloud T., Schaeffer-Reiss C., Rompais M.,
RA   Ayoub D., Lane L., Bairoch A., Van Dorsselaer A., Carapito C.;
RT   "N-terminome analysis of the human mitochondrial proteome.";
RL   Proteomics 15:2519-2524(2015).
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DR   EMBL; AC027808; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC068870; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; H0YLI4; -.
DR   jPOST; H0YLI4; -.
DR   MaxQB; H0YLI4; -.
DR   PeptideAtlas; H0YLI4; -.
DR   PRIDE; H0YLI4; -.
DR   Ensembl; ENST00000559537; ENSP00000453220; ENSG00000117899.
DR   UCSC; uc059mku.1; human.
DR   EuPathDB; HostDB:ENSG00000117899.10; -.
DR   HGNC; HGNC:13520; MESD.
DR   OpenTargets; ENSG00000117899; -.
DR   eggNOG; KOG4357; Eukaryota.
DR   eggNOG; ENOG4111SG4; LUCA.
DR   GeneTree; ENSGT00390000000993; -.
DR   ChiTaRS; MESDC2; human.
DR   Proteomes; UP000005640; Chromosome 15.
DR   Bgee; ENSG00000117899; Expressed in 206 organ(s), highest expression level in layer of synovial tissue.
DR   ExpressionAtlas; H0YLI4; baseline and differential.
DR   GO; GO:0006457; P:protein folding; IEA:InterPro.
DR   InterPro; IPR019330; MESD.
DR   Pfam; PF10185; Mesd; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|EPD:H0YLI4,
KW   ECO:0000213|MaxQB:H0YLI4, ECO:0000213|PeptideAtlas:H0YLI4};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     33       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        34     80       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003546510.
SQ   SEQUENCE   80 AA;  8701 MW;  89FB55A5E45ECD57 CRC64;
     MAASRWARKA VVLLCASDLL LLLLLLPPPG SCAAEGSPGT PDESTPPPRK KKKDIRDYND
     ADMARLLEQW EANTCPTSTH
//