ID   H0YLC1_HUMAN            Unreviewed;        95 AA.
AC   H0YLC1;
DT   22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT   22-FEB-2012, sequence version 1.
DT   05-DEC-2018, entry version 46.
DE   SubName: Full=Probable phospholipid-transporting ATPase IM {ECO:0000313|Ensembl:ENSP00000453143};
DE   Flags: Fragment;
GN   Name=ATP8B4 {ECO:0000313|Ensembl:ENSP00000453143};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000453143, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000453143, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16572171; DOI=10.1038/nature04601;
RA   Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K.,
RA   Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K.,
RA   FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N.,
RA   Abouelleil A., Arachchi H.M., Baradarani L., Birditt B., Bloom S.,
RA   Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K.,
RA   DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R.,
RA   Fahey J., Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G.,
RA   Johnson E., Jones C., Kamat A., Kaur A., Locke D.P., Madan A.,
RA   Munson G., Jaffe D.B., Lui A., Macdonald P., Mauceli E., Naylor J.W.,
RA   Nesbitt R., Nicol R., O'Leary S.B., Ratcliffe A., Rounsley S., She X.,
RA   Sneddon K.M., Stewart S., Sougnez C., Stone S.M., Topham K.,
RA   Vincent D., Wang S., Zimmer A.R., Birren B.W., Hood L., Lander E.S.,
RA   Nusbaum C.;
RT   "Analysis of the DNA sequence and duplication history of human
RT   chromosome 15.";
RL   Nature 440:671-675(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000453143}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JAN-2012) to UniProtKB.
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DR   EMBL; AC009753; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC016045; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC025040; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF456044; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; H0YLC1; -.
DR   PeptideAtlas; H0YLC1; -.
DR   PRIDE; H0YLC1; -.
DR   Ensembl; ENST00000558024; ENSP00000453143; ENSG00000104043.
DR   UCSC; uc059jcp.1; human.
DR   EuPathDB; HostDB:ENSG00000104043.14; -.
DR   HGNC; HGNC:13536; ATP8B4.
DR   OpenTargets; ENSG00000104043; -.
DR   eggNOG; KOG0206; Eukaryota.
DR   eggNOG; COG0474; LUCA.
DR   GeneTree; ENSGT00940000160101; -.
DR   ChiTaRS; ATP8B4; human.
DR   Proteomes; UP000005640; Chromosome 15.
DR   Bgee; ENSG00000104043; Expressed in 132 organ(s), highest expression level in bone marrow.
DR   ExpressionAtlas; H0YLC1; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0004012; F:phospholipid-translocating ATPase activity; IEA:InterPro.
DR   InterPro; IPR030348; ATP8B4.
DR   InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
DR   InterPro; IPR006539; P-type_ATPase_IV.
DR   InterPro; IPR032631; P-type_ATPase_N.
DR   PANTHER; PTHR24092; PTHR24092; 1.
DR   PANTHER; PTHR24092:SF80; PTHR24092:SF80; 1.
DR   Pfam; PF16209; PhoLip_ATPase_N; 1.
DR   SUPFAM; SSF81665; SSF81665; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     20       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        21     95       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003546507.
FT   DOMAIN        2     27       PhoLip_ATPase_N.
FT                                {ECO:0000259|Pfam:PF16209}.
FT   NON_TER       1      1       {ECO:0000313|Ensembl:ENSP00000453143}.
SQ   SEQUENCE   95 AA;  10921 MW;  C1EF72452A921B8C CRC64;
     XANAYFLCLL ILQLIPEISS LTWFTTIVPL VLVITMTAVK DATDDYFRHK SDNQVNNRQS
     EVLINSKLQN EKWMNVKVGD IIKLENNQFV ALIKD
//