ID   H0YKA5_HUMAN            Unreviewed;        43 AA.
AC   H0YKA5;
DT   22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT   22-FEB-2012, sequence version 1.
DT   16-JAN-2019, entry version 40.
DE   SubName: Full=Ras GTPase-activating-like protein IQGAP1 {ECO:0000313|Ensembl:ENSP00000452723};
DE   Flags: Fragment;
GN   Name=IQGAP1 {ECO:0000313|Ensembl:ENSP00000452723};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000452723, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000452723, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16572171; DOI=10.1038/nature04601;
RA   Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K.,
RA   Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K.,
RA   FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N.,
RA   Abouelleil A., Arachchi H.M., Baradarani L., Birditt B., Bloom S.,
RA   Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K.,
RA   DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R.,
RA   Fahey J., Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G.,
RA   Johnson E., Jones C., Kamat A., Kaur A., Locke D.P., Madan A.,
RA   Munson G., Jaffe D.B., Lui A., Macdonald P., Mauceli E., Naylor J.W.,
RA   Nesbitt R., Nicol R., O'Leary S.B., Ratcliffe A., Rounsley S., She X.,
RA   Sneddon K.M., Stewart S., Sougnez C., Stone S.M., Topham K.,
RA   Vincent D., Wang S., Zimmer A.R., Birren B.W., Hood L., Lander E.S.,
RA   Nusbaum C.;
RT   "Analysis of the DNA sequence and duplication history of human
RT   chromosome 15.";
RL   Nature 440:671-675(2006).
RN   [2] {ECO:0000213|PubMed:21269460}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA   Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P.,
RA   Burckstummer T., Bennett K.L., Superti-Furga G., Colinge J.;
RT   "Initial characterization of the human central proteome.";
RL   BMC Syst. Biol. 5:17-17(2011).
RN   [3] {ECO:0000313|Ensembl:ENSP00000452723}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JAN-2012) to UniProtKB.
RN   [4] {ECO:0000213|PubMed:25944712}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=25944712;
RA   Vaca Jacome A.S., Rabilloud T., Schaeffer-Reiss C., Rompais M.,
RA   Ayoub D., Lane L., Bairoch A., Van Dorsselaer A., Carapito C.;
RT   "N-terminome analysis of the human mitochondrial proteome.";
RL   Proteomics 15:2519-2524(2015).
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DR   EMBL; AC018946; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC103739; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   jPOST; H0YKA5; -.
DR   MaxQB; H0YKA5; -.
DR   PeptideAtlas; H0YKA5; -.
DR   PRIDE; H0YKA5; -.
DR   Ensembl; ENST00000560418; ENSP00000452723; ENSG00000140575.
DR   UCSC; uc059nev.1; human.
DR   EuPathDB; HostDB:ENSG00000140575.12; -.
DR   HGNC; HGNC:6110; IQGAP1.
DR   OpenTargets; ENSG00000140575; -.
DR   eggNOG; KOG2128; Eukaryota.
DR   eggNOG; COG5261; LUCA.
DR   GeneTree; ENSGT00940000153810; -.
DR   ChiTaRS; IQGAP1; human.
DR   Proteomes; UP000005640; Chromosome 15.
DR   Bgee; ENSG00000140575; Expressed in 236 organ(s), highest expression level in oviduct epithelium.
DR   ExpressionAtlas; H0YKA5; baseline and differential.
DR   Gene3D; 1.10.418.10; -; 1.
DR   InterPro; IPR036872; CH_dom_sf.
DR   SUPFAM; SSF47576; SSF47576; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|EPD:H0YKA5,
KW   ECO:0000213|MaxQB:H0YKA5, ECO:0000213|PeptideAtlas:H0YKA5};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     21       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        22     43       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003546031.
FT   NON_TER      43     43       {ECO:0000313|Ensembl:ENSP00000452723}.
SQ   SEQUENCE   43 AA;  5021 MW;  8B497482FB0EC7A8 CRC64;
     MPRCIYCIHA LSLYLFKLGL APQIQDLYGK VDFTEEEINN MKT
//