ID   H0YHS5_HUMAN            Unreviewed;       199 AA.
AC   H0YHS5;
DT   22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT   22-FEB-2012, sequence version 1.
DT   16-JAN-2019, entry version 39.
DE   SubName: Full=HEAT repeat-containing protein 5A {ECO:0000313|Ensembl:ENSP00000447708};
DE   Flags: Fragment;
GN   Name=HEATR5A {ECO:0000313|Ensembl:ENSP00000447708};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000447708, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000447708, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12508121; DOI=10.1038/nature01348;
RA   Heilig R., Eckenberg R., Petit J.-L., Fonknechten N., Da Silva C.,
RA   Cattolico L., Levy M., Barbe V., De Berardinis V., Ureta-Vidal A.,
RA   Pelletier E., Vico V., Anthouard V., Rowen L., Madan A., Qin S.,
RA   Sun H., Du H., Pepin K., Artiguenave F., Robert C., Cruaud C.,
RA   Bruels T., Jaillon O., Friedlander L., Samson G., Brottier P.,
RA   Cure S., Segurens B., Aniere F., Samain S., Crespeau H., Abbasi N.,
RA   Aiach N., Boscus D., Dickhoff R., Dors M., Dubois I., Friedman C.,
RA   Gouyvenoux M., James R., Madan A., Mairey-Estrada B., Mangenot S.,
RA   Martins N., Menard M., Oztas S., Ratcliffe A., Shaffer T., Trask B.,
RA   Vacherie B., Bellemere C., Belser C., Besnard-Gonnet M.,
RA   Bartol-Mavel D., Boutard M., Briez-Silla S., Combette S.,
RA   Dufosse-Laurent V., Ferron C., Lechaplais C., Louesse C., Muselet D.,
RA   Magdelenat G., Pateau E., Petit E., Sirvain-Trukniewicz P., Trybou A.,
RA   Vega-Czarny N., Bataille E., Bluet E., Bordelais I., Dubois M.,
RA   Dumont C., Guerin T., Haffray S., Hammadi R., Muanga J., Pellouin V.,
RA   Robert D., Wunderle E., Gauguet G., Roy A., Sainte-Marthe L.,
RA   Verdier J., Verdier-Discala C., Hillier L.W., Fulton L., McPherson J.,
RA   Matsuda F., Wilson R., Scarpelli C., Gyapay G., Wincker P., Saurin W.,
RA   Quetier F., Waterston R., Hood L., Weissenbach J.;
RT   "The DNA sequence and analysis of human chromosome 14.";
RL   Nature 421:601-607(2003).
RN   [2] {ECO:0000213|PubMed:18691976}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=18691976; DOI=10.1016/j.molcel.2008.07.007;
RA   Daub H., Olsen J.V., Bairlein M., Gnad F., Oppermann F.S., Korner R.,
RA   Greff Z., Keri G., Stemmann O., Mann M.;
RT   "Kinase-selective enrichment enables quantitative phosphoproteomics of
RT   the kinome across the cell cycle.";
RL   Mol. Cell 31:438-448(2008).
RN   [3] {ECO:0000313|Ensembl:ENSP00000447708}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JAN-2012) to UniProtKB.
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DR   EMBL; AL136418; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AL139353; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; H0YHS5; -.
DR   jPOST; H0YHS5; -.
DR   MaxQB; H0YHS5; -.
DR   PeptideAtlas; H0YHS5; -.
DR   Ensembl; ENST00000549719; ENSP00000447708; ENSG00000129493.
DR   UCSC; uc059aom.1; human.
DR   EuPathDB; HostDB:ENSG00000129493.14; -.
DR   HGNC; HGNC:20276; HEATR5A.
DR   OpenTargets; ENSG00000129493; -.
DR   eggNOG; KOG1822; Eukaryota.
DR   eggNOG; ENOG410XP05; LUCA.
DR   GeneTree; ENSGT00390000006205; -.
DR   ChiTaRS; HEATR5A; human.
DR   Proteomes; UP000005640; Chromosome 14.
DR   Bgee; ENSG00000129493; Expressed in 199 organ(s), highest expression level in corpus callosum.
DR   ExpressionAtlas; H0YHS5; baseline and differential.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR040108; Laa1/Sip1/HEATR5/SWEETIE.
DR   PANTHER; PTHR21663; PTHR21663; 1.
DR   SUPFAM; SSF48371; SSF48371; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:H0YHS5,
KW   ECO:0000213|PeptideAtlas:H0YHS5};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     16       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        17    199       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003545951.
FT   NON_TER       1      1       {ECO:0000313|Ensembl:ENSP00000447708}.
FT   NON_TER     199    199       {ECO:0000313|Ensembl:ENSP00000447708}.
SQ   SEQUENCE   199 AA;  21952 MW;  8267FAB29F0247E5 CRC64;
     XSLIIMLLLN VPPTHAEVHQ SLGRCLNALI TTLGPELQGN STSISTLRTS CLLGCAVMQD
     NPDCLVQAQA ISCLQQLHMF APRHVNLSSL VSCLCEILLD NSVLVNLCSP YLLLRRAVLA
     CLRQLVQREA AEVSEHAVML AKDSREELTP DANIREVGLE GALLILLDKE TDERLCHDIK
     ETLNYMLTSM AVEKLSLWL
//