ID   H0YEV8_HUMAN            Unreviewed;       165 AA.
AC   H0YEV8;
DT   22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT   22-FEB-2012, sequence version 1.
DT   16-JAN-2019, entry version 41.
DE   SubName: Full=Synaptojanin-2 {ECO:0000313|Ensembl:ENSP00000436657};
DE   Flags: Fragment;
GN   Name=SYNJ2 {ECO:0000313|Ensembl:ENSP00000436657};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000436657, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000436657, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=14574404; DOI=10.1038/nature02055;
RA   Mungall A.J., Palmer S.A., Sims S.K., Edwards C.A., Ashurst J.L.,
RA   Wilming L., Jones M.C., Horton R., Hunt S.E., Scott C.E.,
RA   Gilbert J.G.R., Clamp M.E., Bethel G., Milne S., Ainscough R.,
RA   Almeida J.P., Ambrose K.D., Andrews T.D., Ashwell R.I.S.,
RA   Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Barker D.J.,
RA   Barlow K.F., Bates K., Beare D.M., Beasley H., Beasley O., Bird C.P.,
RA   Blakey S.E., Bray-Allen S., Brook J., Brown A.J., Brown J.Y.,
RA   Burford D.C., Burrill W., Burton J., Carder C., Carter N.P.,
RA   Chapman J.C., Clark S.Y., Clark G., Clee C.M., Clegg S., Cobley V.,
RA   Collier R.E., Collins J.E., Colman L.K., Corby N.R., Coville G.J.,
RA   Culley K.M., Dhami P., Davies J., Dunn M., Earthrowl M.E.,
RA   Ellington A.E., Evans K.A., Faulkner L., Francis M.D., Frankish A.,
RA   Frankland J., French L., Garner P., Garnett J., Ghori M.J.,
RA   Gilby L.M., Gillson C.J., Glithero R.J., Grafham D.V., Grant M.,
RA   Gribble S., Griffiths C., Griffiths M.N.D., Hall R., Halls K.S.,
RA   Hammond S., Harley J.L., Hart E.A., Heath P.D., Heathcott R.,
RA   Holmes S.J., Howden P.J., Howe K.L., Howell G.R., Huckle E.,
RA   Humphray S.J., Humphries M.D., Hunt A.R., Johnson C.M., Joy A.A.,
RA   Kay M., Keenan S.J., Kimberley A.M., King A., Laird G.K., Langford C.,
RA   Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C.R., Lloyd D.M.,
RA   Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M.,
RA   Maslen G.L., Matthews L., McCann O.T., McLaren S.J., McLay K.,
RA   McMurray A., Moore M.J.F., Mullikin J.C., Niblett D., Nickerson T.,
RA   Novik K.L., Oliver K., Overton-Larty E.K., Parker A., Patel R.,
RA   Pearce A.V., Peck A.I., Phillimore B.J.C.T., Phillips S., Plumb R.W.,
RA   Porter K.M., Ramsey Y., Ranby S.A., Rice C.M., Ross M.T., Searle S.M.,
RA   Sehra H.K., Sheridan E., Skuce C.D., Smith S., Smith M., Spraggon L.,
RA   Squares S.L., Steward C.A., Sycamore N., Tamlyn-Hall G., Tester J.,
RA   Theaker A.J., Thomas D.W., Thorpe A., Tracey A., Tromans A., Tubby B.,
RA   Wall M., Wallis J.M., West A.P., White S.S., Whitehead S.L.,
RA   Whittaker H., Wild A., Willey D.J., Wilmer T.E., Wood J.M., Wray P.W.,
RA   Wyatt J.C., Young L., Younger R.M., Bentley D.R., Coulson A.,
RA   Durbin R., Hubbard T., Sulston J.E., Dunham I., Rogers J., Beck S.;
RT   "The DNA sequence and analysis of human chromosome 6.";
RL   Nature 425:805-811(2003).
RN   [2] {ECO:0000213|PubMed:21269460}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA   Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P.,
RA   Burckstummer T., Bennett K.L., Superti-Furga G., Colinge J.;
RT   "Initial characterization of the human central proteome.";
RL   BMC Syst. Biol. 5:17-17(2011).
RN   [3] {ECO:0000313|Ensembl:ENSP00000436657}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JAN-2012) to UniProtKB.
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DR   EMBL; AL139330; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; H0YEV8; -.
DR   jPOST; H0YEV8; -.
DR   MaxQB; H0YEV8; -.
DR   PeptideAtlas; H0YEV8; -.
DR   PRIDE; H0YEV8; -.
DR   Ensembl; ENST00000485863; ENSP00000436657; ENSG00000078269.
DR   UCSC; uc063sne.1; human.
DR   EuPathDB; HostDB:ENSG00000078269.13; -.
DR   HGNC; HGNC:11504; SYNJ2.
DR   OpenTargets; ENSG00000078269; -.
DR   eggNOG; KOG0566; Eukaryota.
DR   eggNOG; COG5329; LUCA.
DR   eggNOG; COG5411; LUCA.
DR   GeneTree; ENSGT00940000160715; -.
DR   ChiTaRS; SYNJ2; human.
DR   Proteomes; UP000005640; Chromosome 6.
DR   Bgee; ENSG00000078269; Expressed in 236 organ(s), highest expression level in inferior vagus X ganglion.
DR   ExpressionAtlas; H0YEV8; baseline and differential.
DR   GO; GO:0034595; F:phosphatidylinositol phosphate 5-phosphatase activity; IEA:InterPro.
DR   GO; GO:0046856; P:phosphatidylinositol dephosphorylation; IEA:InterPro.
DR   InterPro; IPR002013; SAC_dom.
DR   InterPro; IPR034974; SYNJ2.
DR   PANTHER; PTHR11200:SF148; PTHR11200:SF148; 1.
DR   Pfam; PF02383; Syja_N; 1.
DR   PROSITE; PS50275; SAC; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:H0YEV8,
KW   ECO:0000213|PeptideAtlas:H0YEV8};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     23       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        24    165       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003546704.
FT   DOMAIN        1    145       SAC. {ECO:0000259|PROSITE:PS50275}.
FT   NON_TER       1      1       {ECO:0000313|Ensembl:ENSP00000436657}.
SQ   SEQUENCE   165 AA;  18482 MW;  9B8081025F5346CF CRC64;
     XVSCCDWLLK IICGVVTIRT VYASHKQAKA CLVSRVSCER TGTRFHTRGV NDDGHVSNFV
     ETEQMIYMDD GVSSFVQIRG SVPLFWEQPG LQVGSHHLRL HRGLEANAPA FDRHMVLLKE
     QYGQQVVVNL LGSRGGEEVL NRAFKVRPGC PLHSWAGRQV AMVER
//