ID   H0YDY5_HUMAN            Unreviewed;        93 AA.
AC   H0YDY5;
DT   22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT   22-FEB-2012, sequence version 1.
DT   16-JAN-2019, entry version 34.
DE   SubName: Full=Delta(14)-sterol reductase {ECO:0000313|Ensembl:ENSP00000434598};
DE   Flags: Fragment;
GN   Name=TM7SF2 {ECO:0000313|Ensembl:ENSP00000434598};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000434598, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000434598, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16554811; DOI=10.1038/nature04632;
RA   Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K.,
RA   Lloyd C., Itoh T., Takeda T., Kim D.W., She X., Barlow K.F., Bloom T.,
RA   Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G.,
RA   Jaffe D.B., LaButti K., Nicol R., Park H.S., Seaman C., Sougnez C.,
RA   Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A.,
RA   Hattori M., Rogers J., Lander E.S., Sakaki Y.;
RT   "Human chromosome 11 DNA sequence and analysis including novel gene
RT   identification.";
RL   Nature 440:497-500(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000434598}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JAN-2012) to UniProtKB.
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DR   EMBL; AP003068; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; H0YDY5; -.
DR   jPOST; H0YDY5; -.
DR   MaxQB; H0YDY5; -.
DR   PeptideAtlas; H0YDY5; -.
DR   PRIDE; H0YDY5; -.
DR   Ensembl; ENST00000524690; ENSP00000434598; ENSG00000149809.
DR   UCSC; uc058dfo.1; human.
DR   EuPathDB; HostDB:ENSG00000149809.14; -.
DR   HGNC; HGNC:11863; TM7SF2.
DR   OpenTargets; ENSG00000149809; -.
DR   eggNOG; KOG1435; Eukaryota.
DR   eggNOG; ENOG410XP67; LUCA.
DR   GeneTree; ENSGT00390000000417; -.
DR   ChiTaRS; TM7SF2; human.
DR   Proteomes; UP000005640; Chromosome 11.
DR   Bgee; ENSG00000149809; Expressed in 201 organ(s), highest expression level in right adrenal gland.
DR   ExpressionAtlas; H0YDY5; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR001171; Ergosterol_biosynth_ERG4_ERG24.
DR   Pfam; PF01222; ERG4_ERG24; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Proteomics identification {ECO:0000213|MaxQB:H0YDY5,
KW   ECO:0000213|PeptideAtlas:H0YDY5};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     26       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        27     93       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003546124.
FT   TRANSMEM     50     69       Helical. {ECO:0000256|SAM:Phobius}.
FT   NON_TER       1      1       {ECO:0000313|Ensembl:ENSP00000434598}.
SQ   SEQUENCE   93 AA;  9944 MW;  53939512B4E0262E CRC64;
     XEFGGPLGAA ALLLLLPATM FHLLLAARSG PARLLGPPAS LPGLEVLWSP RALLLWLAWL
     GLQAALYLLP ARKVAEGQEL KDKSRLRYPI NGA
//