ID   H0YCW6_HUMAN            Unreviewed;       207 AA.
AC   H0YCW6;
DT   22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT   22-FEB-2012, sequence version 1.
DT   16-JAN-2019, entry version 39.
DE   RecName: Full=Mannosyltransferase {ECO:0000256|RuleBase:RU363075};
DE            EC=2.4.1.- {ECO:0000256|RuleBase:RU363075};
DE   Flags: Fragment;
GN   Name=ALG9 {ECO:0000313|Ensembl:ENSP00000432442};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000432442, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000432442, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16554811; DOI=10.1038/nature04632;
RA   Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K.,
RA   Lloyd C., Itoh T., Takeda T., Kim D.W., She X., Barlow K.F., Bloom T.,
RA   Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G.,
RA   Jaffe D.B., LaButti K., Nicol R., Park H.S., Seaman C., Sougnez C.,
RA   Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A.,
RA   Hattori M., Rogers J., Lander E.S., Sakaki Y.;
RT   "Human chromosome 11 DNA sequence and analysis including novel gene
RT   identification.";
RL   Nature 440:497-500(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000432442}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JAN-2012) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC       {ECO:0000256|RuleBase:RU363075}; Multi-pass membrane protein
CC       {ECO:0000256|RuleBase:RU363075}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 22 family.
CC       {ECO:0000256|RuleBase:RU363075}.
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DR   EMBL; AP001781; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; FP884232; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF511118; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   jPOST; H0YCW6; -.
DR   MaxQB; H0YCW6; -.
DR   PeptideAtlas; H0YCW6; -.
DR   PRIDE; H0YCW6; -.
DR   Ensembl; ENST00000532425; ENSP00000432442; ENSG00000086848.
DR   UCSC; uc058hfd.1; human.
DR   EuPathDB; HostDB:ENSG00000086848.14; -.
DR   HGNC; HGNC:15672; ALG9.
DR   OpenTargets; ENSG00000086848; -.
DR   eggNOG; KOG2515; Eukaryota.
DR   eggNOG; ENOG410XP6D; LUCA.
DR   GeneTree; ENSGT00940000153721; -.
DR   Proteomes; UP000005640; Chromosome 11.
DR   Bgee; ENSG00000086848; Expressed in 184 organ(s), highest expression level in small intestine Peyer's patch.
DR   ExpressionAtlas; H0YCW6; baseline and differential.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0000030; F:mannosyltransferase activity; IEA:InterPro.
DR   InterPro; IPR039484; ALG9-like.
DR   InterPro; IPR005599; GPI_mannosylTrfase.
DR   PANTHER; PTHR22760; PTHR22760; 1.
DR   PANTHER; PTHR22760:SF2; PTHR22760:SF2; 1.
DR   Pfam; PF03901; Glyco_transf_22; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Endoplasmic reticulum {ECO:0000256|RuleBase:RU363075};
KW   Glycosyltransferase {ECO:0000256|RuleBase:RU363075};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transferase {ECO:0000256|RuleBase:RU363075}.
FT   SIGNAL        1     17       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        18    207       Mannosyltransferase.
FT                                {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003546113.
FT   NON_TER       1      1       {ECO:0000313|Ensembl:ENSP00000432442}.
SQ   SEQUENCE   207 AA;  24310 MW;  2CF6D45C6AC747B0 CRC64;
     XTVFLFGLLS FSRSVALFRG YHGPLDLYPE FYRIATDPTI HTVPEGRPVN VCVGKEWYRF
     PSSFLLPDNW QLQFIPSEFR GQLPKPFAEG PLATRIVPTD MNDQNLEEPS RYIDISKCHY
     LVDLDTMRET PREPKYSSNK EEWISLAYRP FLDASRSSKL LRAFYVPFLS DQYTVYVNYT
     ILKPRKAKQI RKKSGDRRRA EPTYRKN
//