ID   H0Y773_HUMAN            Unreviewed;       212 AA.
AC   H0Y773;
DT   22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT   22-FEB-2012, sequence version 1.
DT   16-JAN-2019, entry version 35.
DE   SubName: Full=Immunoglobulin superfamily member 23 {ECO:0000313|Ensembl:ENSP00000410629};
DE   Flags: Fragment;
GN   Name=IGSF23 {ECO:0000313|Ensembl:ENSP00000410629};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000410629, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000410629, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15057824; DOI=10.1038/nature02399;
RA   Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J.,
RA   Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M.,
RA   Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E.,
RA   Caenepeel S., Carrano A.V., Caoile C., Chan Y.M., Christensen M.,
RA   Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C.,
RA   Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M.,
RA   Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T.,
RA   Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H.,
RA   Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S.,
RA   Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J.,
RA   Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M.,
RA   Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J.,
RA   Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D.,
RA   Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A.,
RA   Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I.,
RA   Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA   Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA   Rubin E.M., Lucas S.M.;
RT   "The DNA sequence and biology of human chromosome 19.";
RL   Nature 428:529-535(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000410629}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JAN-2012) to UniProtKB.
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DR   EMBL; AC243964; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; H0Y773; -.
DR   PRIDE; H0Y773; -.
DR   Ensembl; ENST00000428245; ENSP00000410629; ENSG00000216588.
DR   UCSC; uc060zsm.1; human.
DR   EuPathDB; HostDB:ENSG00000216588.8; -.
DR   HGNC; HGNC:40040; IGSF23.
DR   OpenTargets; ENSG00000216588; -.
DR   eggNOG; ENOG410J23I; Eukaryota.
DR   eggNOG; ENOG41118KY; LUCA.
DR   GeneTree; ENSGT00390000015308; -.
DR   OMA; NGVPCGM; -.
DR   PhylomeDB; H0Y773; -.
DR   Proteomes; UP000005640; Chromosome 19.
DR   Bgee; ENSG00000216588; Expressed in 67 organ(s), highest expression level in liver.
DR   ExpressionAtlas; H0Y773; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   SUPFAM; SSF48726; SSF48726; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     34       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        35    212       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003545876.
FT   TRANSMEM    175    198       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       37    148       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   NON_TER       1      1       {ECO:0000313|Ensembl:ENSP00000410629}.
SQ   SEQUENCE   212 AA;  22697 MW;  ECF9632AAEBD82B6 CRC64;
     XRGPLDVSSS HTPTWRKLLL TGALLTSCTC SAFSELPFSA QLNTLTEGAS VHLPVPGRLE
     DSLQLMPLKT FPAAIRGVIQ SELNYSVILQ WVVTMDPEPV LSWTFSGVPC GMGEKLFIRR
     LSCEQLGTYM CIATNSKKQL VSEPVTISLP KPIMQPTEAE PMEPDPTLSL SGGSAIGLLA
     AGILGAGALI AGMCFIIIQS LRTDRQRIGI CS
//