ID   H0Y714_HUMAN            Unreviewed;       280 AA.
AC   H0Y714;
DT   22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT   22-FEB-2012, sequence version 1.
DT   16-JAN-2019, entry version 40.
DE   SubName: Full=U3 small nucleolar ribonucleoprotein protein IMP4 {ECO:0000313|Ensembl:ENSP00000409371};
DE   Flags: Fragment;
GN   Name=IMP4 {ECO:0000313|Ensembl:ENSP00000409371};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000409371, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000409371, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15815621; DOI=10.1038/nature03466;
RA   Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H.,
RA   Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M.,
RA   Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E.,
RA   Kremitzki C., Oddy L., Du H., Sun H., Bradshaw-Cordum H., Ali J.,
RA   Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C.,
RA   Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J.,
RA   Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A.,
RA   Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K.,
RA   Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M.,
RA   Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K.,
RA   McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C.,
RA   Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N.,
RA   Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M.,
RA   Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E.,
RA   Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P.,
RA   Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A.,
RA   Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A.,
RA   Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T.,
RA   Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D.,
RA   Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X.,
RA   McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C.,
RA   Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S.,
RA   Miller W., Eichler E.E., Bork P., Suyama M., Torrents D.,
RA   Waterston R.H., Wilson R.K.;
RT   "Generation and annotation of the DNA sequences of human chromosomes 2
RT   and 4.";
RL   Nature 434:724-731(2005).
RN   [2] {ECO:0000313|Ensembl:ENSP00000409371}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JAN-2012) to UniProtKB.
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DR   EMBL; AC132479; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; H0Y714; -.
DR   IntAct; H0Y714; 7.
DR   EPD; H0Y714; -.
DR   jPOST; H0Y714; -.
DR   MaxQB; H0Y714; -.
DR   PeptideAtlas; H0Y714; -.
DR   PRIDE; H0Y714; -.
DR   Ensembl; ENST00000452955; ENSP00000409371; ENSG00000136718.
DR   UCSC; uc061nub.1; human.
DR   EuPathDB; HostDB:ENSG00000136718.9; -.
DR   HGNC; HGNC:30856; IMP4.
DR   OpenTargets; ENSG00000136718; -.
DR   eggNOG; KOG2781; Eukaryota.
DR   eggNOG; COG2136; LUCA.
DR   GeneTree; ENSGT00940000153231; -.
DR   ChiTaRS; IMP4; human.
DR   Proteomes; UP000005640; Chromosome 2.
DR   Bgee; ENSG00000136718; Expressed in 222 organ(s), highest expression level in body of pancreas.
DR   ExpressionAtlas; H0Y714; baseline and differential.
DR   GO; GO:0001650; C:fibrillar center; IDA:HPA.
DR   GO; GO:0005730; C:nucleolus; IDA:HPA.
DR   InterPro; IPR007109; Brix.
DR   Pfam; PF04427; Brix; 1.
DR   SMART; SM00879; Brix; 1.
DR   PROSITE; PS50833; BRIX; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|EPD:H0Y714,
KW   ECO:0000213|MaxQB:H0Y714, ECO:0000213|PeptideAtlas:H0Y714};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     20       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        21    280       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003546048.
FT   DOMAIN       72    253       Brix. {ECO:0000259|PROSITE:PS50833}.
FT   NON_TER       1      1       {ECO:0000313|Ensembl:ENSP00000409371}.
SQ   SEQUENCE   280 AA;  31947 MW;  5CCACDBC72F9E0E1 CRC64;
     XSKCLPAVFL AHWVLLLVLR VFLPCDENRL IPTELRREAL ALQGSLEFDD AGGEGVTSHV
     DDEYRWAGVE DPKVMITTSR DPSSRLKMFA KELKLVFPGA QRMNRGRHEV GALVRACKAN
     GVTDLLVVHE HRGTPVGLIV SHLPFGPTAY FTLCNVVMRH DIPDLGTMSE AKPHLITHGF
     SSRLGKRVSD ILRYLFPVPK DDSHRVITFA NQDDYISFRH HVYKKTDHRN VELTEVGPRF
     ELKLYMIRLG TLEQEATADV EWRWHPYTNT ARKRVFLSTE
//