ID   G8JLG8_HUMAN            Unreviewed;       823 AA.
AC   G8JLG8;
DT   25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT   25-JAN-2012, sequence version 1.
DT   16-JAN-2019, entry version 47.
DE   SubName: Full=Uncharacterized protein C1orf127 {ECO:0000313|Ensembl:ENSP00000366203};
GN   Name=C1orf127 {ECO:0000313|Ensembl:ENSP00000366203};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000366203, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000366203, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16710414; DOI=10.1038/nature04727;
RA   Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D.,
RA   Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.,
RA   Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F.,
RA   McDonald L., Evans R., Phillips K., Atkinson A., Cooper R., Jones C.,
RA   Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P.,
RA   Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I., Aubin K.,
RA   Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G.,
RA   Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D.,
RA   Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G.,
RA   Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J.,
RA   Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H.,
RA   Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L.,
RA   Ghori M.R., Gibson R., Gilby L.M., Gillett W., Glithero R.J.,
RA   Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R.,
RA   Hammond S., Harrison E.S., Hart E., Haugen E., Heath P.D., Holmes S.,
RA   Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J.,
RA   James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K.,
RA   Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G.,
RA   Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J.,
RA   Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L.,
RA   Matthews N.S., McLaren S., Milne S., Mistry S., Moore M.J.,
RA   Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A.,
RA   Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K.,
RA   Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G.,
RA   Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S.,
RA   Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N.,
RA   Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S.,
RA   Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L.,
RA   Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.,
RA   Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T.,
RA   Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R., Banerjee R.,
RA   Bryant S.P., Burford D.C., Burrill W.D., Clegg S.M., Dhami P.,
RA   Dovey O., Faulkner L.M., Gribble S.M., Langford C.F., Pandian R.D.,
RA   Porter K.M., Prigmore E.;
RT   "The DNA sequence and biological annotation of human chromosome 1.";
RL   Nature 441:315-321(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000366203}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2011) to UniProtKB.
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DR   EMBL; AL358492; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; NP_001164225.1; NM_001170754.1.
DR   UniGene; Hs.127026; -.
DR   ProteinModelPortal; G8JLG8; -.
DR   iPTMnet; G8JLG8; -.
DR   PRIDE; G8JLG8; -.
DR   Ensembl; ENST00000377004; ENSP00000366203; ENSG00000175262.
DR   GeneID; 148345; -.
DR   KEGG; hsa:148345; -.
DR   UCSC; uc010oao.2; human.
DR   CTD; 148345; -.
DR   EuPathDB; HostDB:ENSG00000175262.14; -.
DR   HGNC; HGNC:26730; C1orf127.
DR   OpenTargets; ENSG00000175262; -.
DR   eggNOG; ENOG410IJNG; Eukaryota.
DR   eggNOG; ENOG410YSYD; LUCA.
DR   GeneTree; ENSGT00390000003592; -.
DR   OMA; FMVTENK; -.
DR   OrthoDB; 1228168at2759; -.
DR   PhylomeDB; G8JLG8; -.
DR   TreeFam; TF338179; -.
DR   GenomeRNAi; 148345; -.
DR   Proteomes; UP000005640; Chromosome 1.
DR   Bgee; ENSG00000175262; Expressed in 71 organ(s), highest expression level in muscle of leg.
DR   ExpressionAtlas; G8JLG8; baseline and differential.
DR   Genevisible; G8JLG8; HS.
DR   InterPro; IPR027956; DUF4556.
DR   PANTHER; PTHR38653; PTHR38653; 1.
DR   Pfam; PF15094; DUF4556; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     22       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        23    823       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003510497.
SQ   SEQUENCE   823 AA;  89019 MW;  ACA299EDE05DE952 CRC64;
     MWGSPALAWA VWLACVQPTV FPWSLSFRSD TDKPSSAAEV LTEASSCWTD TVECFSDYMT
     LWIPRSHVEG LRRWLARTLH LPGTWRSPDH LDSSLAKCGY FLHLASDGDF LFRVQYSACF
     VQKEKANYRL EIRIFQKGVM GLERSDRYIM KCPMLRSRLG QESVHCGPMF IQVSRPLPLW
     RDNRQTPWLL SLRGELVASL EDASLMGLYV DMNATTVTVQ SPRQGLLQRW EVLNTSAELL
     PLWLVSGHHA YSLEAACPPV SFQPESEVLV HIPKQRLGLV KRGSYIEETL SLRFLRVHQS
     NIFMVTENKD FVVVSIPAAG VLQVQRCQEV GGTPGTQAFY RVDLSLEFAE MAAPVLWTVE
     SFFQCVGSGT ESPASTAALR TTPSPPSPGP ETPPAGVPPA ASSQVWAAGP AAQEWLSRDL
     LHRPSDALAK KGLGPFLQTA KPARRGQTSA SILPRVVQAQ RGPQPPPGEA GIPGHPTPPA
     TLPSEPVEGV QASPWRPRPV LPTHPALTLP VSSDASSPSP PAPRPERPES LLVSGPSVTL
     TEGLGTVRPE QDPAKSPGSP LLLRGLSSGD VAAPEPIMGE PGQASEEFQP LARPWRATLA
     AEELVSHRSP GEPQETCSGT EVERPRQTGP GLPREGARGH MDLSSSEPSQ DIEGPGLSIL
     PARDATFSTP SVRQPDPSAW LSSGPELTGM PRVRLAAPLA VLPMEPLPPE PVRPAALLTP
     EASSVGGPDQ ARYLESAPGW PVGQEEWGVA HTSSPPSTQT LSLWAPTGVL LPSLVELEYP
     FQAGRGASLQ QELTEPTLAL SAESHRPPEL QDSVEGLSER PSR
//