ID   G8JLG2_HUMAN            Unreviewed;       529 AA.
AC   G8JLG2;
DT   25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT   25-JAN-2012, sequence version 1.
DT   13-FEB-2019, entry version 47.
DE   SubName: Full=CDSN {ECO:0000313|EMBL:AQY77255.1};
DE   SubName: Full=Corneodesmosin {ECO:0000313|Ensembl:ENSP00000365465};
GN   Name=CDSN {ECO:0000313|Ensembl:ENSP00000365465};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000365465, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000365465, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=14574404; DOI=10.1038/nature02055;
RA   Mungall A.J., Palmer S.A., Sims S.K., Edwards C.A., Ashurst J.L.,
RA   Wilming L., Jones M.C., Horton R., Hunt S.E., Scott C.E.,
RA   Gilbert J.G.R., Clamp M.E., Bethel G., Milne S., Ainscough R.,
RA   Almeida J.P., Ambrose K.D., Andrews T.D., Ashwell R.I.S.,
RA   Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Barker D.J.,
RA   Barlow K.F., Bates K., Beare D.M., Beasley H., Beasley O., Bird C.P.,
RA   Blakey S.E., Bray-Allen S., Brook J., Brown A.J., Brown J.Y.,
RA   Burford D.C., Burrill W., Burton J., Carder C., Carter N.P.,
RA   Chapman J.C., Clark S.Y., Clark G., Clee C.M., Clegg S., Cobley V.,
RA   Collier R.E., Collins J.E., Colman L.K., Corby N.R., Coville G.J.,
RA   Culley K.M., Dhami P., Davies J., Dunn M., Earthrowl M.E.,
RA   Ellington A.E., Evans K.A., Faulkner L., Francis M.D., Frankish A.,
RA   Frankland J., French L., Garner P., Garnett J., Ghori M.J.,
RA   Gilby L.M., Gillson C.J., Glithero R.J., Grafham D.V., Grant M.,
RA   Gribble S., Griffiths C., Griffiths M.N.D., Hall R., Halls K.S.,
RA   Hammond S., Harley J.L., Hart E.A., Heath P.D., Heathcott R.,
RA   Holmes S.J., Howden P.J., Howe K.L., Howell G.R., Huckle E.,
RA   Humphray S.J., Humphries M.D., Hunt A.R., Johnson C.M., Joy A.A.,
RA   Kay M., Keenan S.J., Kimberley A.M., King A., Laird G.K., Langford C.,
RA   Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C.R., Lloyd D.M.,
RA   Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M.,
RA   Maslen G.L., Matthews L., McCann O.T., McLaren S.J., McLay K.,
RA   McMurray A., Moore M.J.F., Mullikin J.C., Niblett D., Nickerson T.,
RA   Novik K.L., Oliver K., Overton-Larty E.K., Parker A., Patel R.,
RA   Pearce A.V., Peck A.I., Phillimore B.J.C.T., Phillips S., Plumb R.W.,
RA   Porter K.M., Ramsey Y., Ranby S.A., Rice C.M., Ross M.T., Searle S.M.,
RA   Sehra H.K., Sheridan E., Skuce C.D., Smith S., Smith M., Spraggon L.,
RA   Squares S.L., Steward C.A., Sycamore N., Tamlyn-Hall G., Tester J.,
RA   Theaker A.J., Thomas D.W., Thorpe A., Tracey A., Tromans A., Tubby B.,
RA   Wall M., Wallis J.M., West A.P., White S.S., Whitehead S.L.,
RA   Whittaker H., Wild A., Willey D.J., Wilmer T.E., Wood J.M., Wray P.W.,
RA   Wyatt J.C., Young L., Younger R.M., Bentley D.R., Coulson A.,
RA   Durbin R., Hubbard T., Sulston J.E., Dunham I., Rogers J., Beck S.;
RT   "The DNA sequence and analysis of human chromosome 6.";
RL   Nature 425:805-811(2003).
RN   [2] {ECO:0000313|Ensembl:ENSP00000365465}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2011) to UniProtKB.
RN   [3] {ECO:0000313|EMBL:AQY77255.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Norman P.J., Norberg S.J., Nemat-Gorgani N., Ronaghi M., Parham P.;
RT   "CDS alleles of MHC region genes derived from homozygous
RT   individuals.";
RL   Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; AL662844; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KY500785; AQY77255.1; -; Genomic_DNA.
DR   RefSeq; NP_001255.3; NM_001264.4.
DR   UniGene; Hs.310958; -.
DR   UniGene; Hs.556031; -.
DR   ProteinModelPortal; G8JLG2; -.
DR   jPOST; G8JLG2; -.
DR   MaxQB; G8JLG2; -.
DR   PRIDE; G8JLG2; -.
DR   Ensembl; ENST00000376288; ENSP00000365465; ENSG00000204539.
DR   GeneID; 1041; -.
DR   UCSC; uc003nsm.3; human.
DR   EuPathDB; HostDB:ENSG00000204539.3; -.
DR   HGNC; HGNC:1802; CDSN.
DR   OpenTargets; ENSG00000204539; -.
DR   eggNOG; ENOG410IENZ; Eukaryota.
DR   eggNOG; ENOG41118PZ; LUCA.
DR   GeneTree; ENSGT00730000111474; -.
DR   OMA; LQPCGSK; -.
DR   PhylomeDB; G8JLG2; -.
DR   Proteomes; UP000005640; Chromosome 6.
DR   Bgee; ENSG00000204539; Expressed in 77 organ(s), highest expression level in skin of leg.
DR   GO; GO:0043589; P:skin morphogenesis; IEA:InterPro.
DR   InterPro; IPR026087; Corneodesmosin.
DR   PANTHER; PTHR23207; PTHR23207; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:G8JLG2,
KW   ECO:0000213|PeptideAtlas:G8JLG2};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     32       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        33    529       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5014574465.
SQ   SEQUENCE   529 AA;  51607 MW;  01BF5C83AE68E772 CRC64;
     MGSSRAPWMG RVGGHGMMAL LLAGLLLPGT LAKSIGTFSD PCKDPTRITS PNDPCLTGKG
     DSSGFSSYSG SSSSGSSISS ARSSGGGSSG SSSGSSIAQG GSAGSFKPGT GYSQVSYSSG
     SGSSLQGASG SSQLGSSSSH SGNSGSHSGS SSSHSSSSSS FQFSSSSFQV GNGSALPTND
     NSYRGILNPS QPGQSSSSSQ TFGVSSSGQS VSSNQRPCSS DIPDSPCSGG PIVSHSGPYI
     PSSHSVSGGQ RPVVVVVDQH GSGAPGVVQG PPCSNGGLPG KPCPPITSVD KSYGGYEVVG
     GSSDSYLVPG MTYSKGKIYP VGYFTKENPV KGSPGVPSFA AGPPISEGKY FSSNPIIPSQ
     SAASSAIAFQ PVGTGGVQLC GGGSTGSKGP CSPSSSRVPS SSSISSSSGL PYHPCGSASQ
     SPCSPPGTGS FSSSSSSQSS GKIILQPCGS KSSSSGHPCM SVSSLTLTGG PDGSPHPDPS
     AGAKPCGSSS AGKIPCRSIR DILAQVKPLG PQLADPEVFL PQGELLNSP
//