ID   G3V4W7_HUMAN            Unreviewed;        87 AA.
AC   G3V4W7;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   05-DEC-2018, entry version 37.
DE   SubName: Full=Gamma-aminobutyric acid receptor subunit beta-3 {ECO:0000313|Ensembl:ENSP00000452041};
GN   Name=GABRB3 {ECO:0000313|Ensembl:ENSP00000452041};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000452041, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000452041, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16572171; DOI=10.1038/nature04601;
RA   Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K.,
RA   Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K.,
RA   FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N.,
RA   Abouelleil A., Arachchi H.M., Baradarani L., Birditt B., Bloom S.,
RA   Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K.,
RA   DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R.,
RA   Fahey J., Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G.,
RA   Johnson E., Jones C., Kamat A., Kaur A., Locke D.P., Madan A.,
RA   Munson G., Jaffe D.B., Lui A., Macdonald P., Mauceli E., Naylor J.W.,
RA   Nesbitt R., Nicol R., O'Leary S.B., Ratcliffe A., Rounsley S., She X.,
RA   Sneddon K.M., Stewart S., Sougnez C., Stone S.M., Topham K.,
RA   Vincent D., Wang S., Zimmer A.R., Birren B.W., Hood L., Lander E.S.,
RA   Nusbaum C.;
RT   "Analysis of the DNA sequence and duplication history of human
RT   chromosome 15.";
RL   Nature 440:671-675(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000452041}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2011) to UniProtKB.
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DR   EMBL; AC009878; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC011196; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC104569; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC127511; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC135999; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC145167; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC145196; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; EU606048; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KC877539; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; G3V4W7; -.
DR   Ensembl; ENST00000555632; ENSP00000452041; ENSG00000166206.
DR   UCSC; uc059gxa.1; human.
DR   EuPathDB; HostDB:ENSG00000166206.13; -.
DR   HGNC; HGNC:4083; GABRB3.
DR   OpenTargets; ENSG00000166206; -.
DR   GeneTree; ENSGT00940000154713; -.
DR   ChiTaRS; GABRB3; human.
DR   Proteomes; UP000005640; Chromosome 15.
DR   Bgee; ENSG00000166206; Expressed in 156 organ(s), highest expression level in pituitary gland.
DR   ExpressionAtlas; G3V4W7; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:InterPro.
DR   GO; GO:0005230; F:extracellular ligand-gated ion channel activity; IEA:InterPro.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   Gene3D; 2.70.170.10; -; 1.
DR   InterPro; IPR006202; Neur_chan_lig-bd.
DR   InterPro; IPR036734; Neur_chan_lig-bd_sf.
DR   InterPro; IPR006201; Neur_channel.
DR   PANTHER; PTHR18945; PTHR18945; 1.
DR   Pfam; PF02931; Neur_chan_LBD; 1.
DR   SUPFAM; SSF63712; SSF63712; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     25       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        26     87       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003457321.
FT   DOMAIN       39     83       Neur_chan_LBD.
FT                                {ECO:0000259|Pfam:PF02931}.
SQ   SEQUENCE   87 AA;  9331 MW;  23AD2DFADB9D1718 CRC64;
     MWGLAGGRLF GIFSAPVLVA VVCCAQSVND PGNMSFVKET VDKLLKGYDI RLRPDFGGPP
     VCVGMNIDIA SIDMVSEVNM AMQELHS
//