ID   G3V4M1_HUMAN            Unreviewed;        92 AA.
AC   G3V4M1;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   16-JAN-2019, entry version 48.
DE   SubName: Full=Melanoma inhibitory activity protein 2 {ECO:0000313|Ensembl:ENSP00000451883};
DE   Flags: Fragment;
GN   Name=MIA2 {ECO:0000313|Ensembl:ENSP00000451883};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000451883, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000451883, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12508121; DOI=10.1038/nature01348;
RA   Heilig R., Eckenberg R., Petit J.-L., Fonknechten N., Da Silva C.,
RA   Cattolico L., Levy M., Barbe V., De Berardinis V., Ureta-Vidal A.,
RA   Pelletier E., Vico V., Anthouard V., Rowen L., Madan A., Qin S.,
RA   Sun H., Du H., Pepin K., Artiguenave F., Robert C., Cruaud C.,
RA   Bruels T., Jaillon O., Friedlander L., Samson G., Brottier P.,
RA   Cure S., Segurens B., Aniere F., Samain S., Crespeau H., Abbasi N.,
RA   Aiach N., Boscus D., Dickhoff R., Dors M., Dubois I., Friedman C.,
RA   Gouyvenoux M., James R., Madan A., Mairey-Estrada B., Mangenot S.,
RA   Martins N., Menard M., Oztas S., Ratcliffe A., Shaffer T., Trask B.,
RA   Vacherie B., Bellemere C., Belser C., Besnard-Gonnet M.,
RA   Bartol-Mavel D., Boutard M., Briez-Silla S., Combette S.,
RA   Dufosse-Laurent V., Ferron C., Lechaplais C., Louesse C., Muselet D.,
RA   Magdelenat G., Pateau E., Petit E., Sirvain-Trukniewicz P., Trybou A.,
RA   Vega-Czarny N., Bataille E., Bluet E., Bordelais I., Dubois M.,
RA   Dumont C., Guerin T., Haffray S., Hammadi R., Muanga J., Pellouin V.,
RA   Robert D., Wunderle E., Gauguet G., Roy A., Sainte-Marthe L.,
RA   Verdier J., Verdier-Discala C., Hillier L.W., Fulton L., McPherson J.,
RA   Matsuda F., Wilson R., Scarpelli C., Gyapay G., Wincker P., Saurin W.,
RA   Quetier F., Waterston R., Hood L., Weissenbach J.;
RT   "The DNA sequence and analysis of human chromosome 14.";
RL   Nature 421:601-607(2003).
RN   [2] {ECO:0000313|Ensembl:ENSP00000451883}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2011) to UniProtKB.
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DR   EMBL; AL132639; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AL157791; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; G3V4M1; -.
DR   jPOST; G3V4M1; -.
DR   MaxQB; G3V4M1; -.
DR   PeptideAtlas; G3V4M1; -.
DR   Ensembl; ENST00000557148; ENSP00000451883; ENSG00000150527.
DR   UCSC; uc059baq.1; human.
DR   EuPathDB; HostDB:ENSG00000150526.11; -.
DR   HGNC; HGNC:18432; MIA2.
DR   OpenTargets; ENSG00000150527; -.
DR   eggNOG; ENOG410IIF2; Eukaryota.
DR   eggNOG; ENOG41118PB; LUCA.
DR   GeneTree; ENSGT00940000153207; -.
DR   ChiTaRS; MIA2; human.
DR   Proteomes; UP000005640; Chromosome 14.
DR   Bgee; ENSG00000150526; Expressed in 68 organ(s), highest expression level in intestine.
DR   ExpressionAtlas; G3V4M1; baseline and differential.
DR   InterPro; IPR036028; SH3-like_dom_sf.
DR   InterPro; IPR001452; SH3_domain.
DR   Pfam; PF07653; SH3_2; 1.
DR   SUPFAM; SSF50044; SSF50044; 1.
DR   PROSITE; PS50002; SH3; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|PeptideAtlas:G3V4M1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   SH3 domain {ECO:0000256|PROSITE-ProRule:PRU00192};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     19       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        20     92       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003457313.
FT   DOMAIN       39     92       SH3. {ECO:0000259|PROSITE:PS50002}.
FT   NON_TER      92     92       {ECO:0000313|Ensembl:ENSP00000451883}.
SQ   SEQUENCE   92 AA;  10392 MW;  F554702AEAD913B7 CRC64;
     MAKFGVHRIL LLAISLTKCL ESTKLLADLK KCGDLECEAL INRVSAMRDY RGPDCRYLNF
     TKGEEISVYV KLAGEREDLW AGSKGKEFGY FP
//