ID   G3V4C2_HUMAN            Unreviewed;        90 AA.
AC   G3V4C2;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   05-DEC-2018, entry version 41.
DE   SubName: Full=Repulsive guidance molecule A {ECO:0000313|Ensembl:ENSP00000451709};
DE   Flags: Fragment;
GN   Name=RGMA {ECO:0000313|Ensembl:ENSP00000451709};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000451709, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000451709, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16572171; DOI=10.1038/nature04601;
RA   Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K.,
RA   Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K.,
RA   FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N.,
RA   Abouelleil A., Arachchi H.M., Baradarani L., Birditt B., Bloom S.,
RA   Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K.,
RA   DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R.,
RA   Fahey J., Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G.,
RA   Johnson E., Jones C., Kamat A., Kaur A., Locke D.P., Madan A.,
RA   Munson G., Jaffe D.B., Lui A., Macdonald P., Mauceli E., Naylor J.W.,
RA   Nesbitt R., Nicol R., O'Leary S.B., Ratcliffe A., Rounsley S., She X.,
RA   Sneddon K.M., Stewart S., Sougnez C., Stone S.M., Topham K.,
RA   Vincent D., Wang S., Zimmer A.R., Birren B.W., Hood L., Lander E.S.,
RA   Nusbaum C.;
RT   "Analysis of the DNA sequence and duplication history of human
RT   chromosome 15.";
RL   Nature 440:671-675(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000451709}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2011) to UniProtKB.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; AC013394; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC087641; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF456122; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF511221; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; G3V4C2; -.
DR   PeptideAtlas; G3V4C2; -.
DR   Ensembl; ENST00000555598; ENSP00000451709; ENSG00000182175.
DR   UCSC; uc059nnd.1; human.
DR   EuPathDB; HostDB:ENSG00000182175.13; -.
DR   HGNC; HGNC:30308; RGMA.
DR   OpenTargets; ENSG00000182175; -.
DR   eggNOG; ENOG410IFAH; Eukaryota.
DR   eggNOG; ENOG410ZT7E; LUCA.
DR   GeneTree; ENSGT00940000153949; -.
DR   ChiTaRS; RGMA; human.
DR   Proteomes; UP000005640; Chromosome 15.
DR   Bgee; ENSG00000182175; Expressed in 178 organ(s), highest expression level in lower esophagus.
DR   ExpressionAtlas; G3V4C2; baseline and differential.
DR   GO; GO:0015026; F:coreceptor activity; IEA:InterPro.
DR   GO; GO:0030509; P:BMP signaling pathway; IEA:InterPro.
DR   GO; GO:0048681; P:negative regulation of axon regeneration; IEA:InterPro.
DR   InterPro; IPR040287; RGM.
DR   InterPro; IPR010536; RGM_N.
DR   InterPro; IPR033607; RGMA.
DR   PANTHER; PTHR31428; PTHR31428; 1.
DR   PANTHER; PTHR31428:SF4; PTHR31428:SF4; 1.
DR   Pfam; PF06535; RGM_N; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|PeptideAtlas:G3V4C2};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     31       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        32     90       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003457307.
FT   DOMAIN       32     90       RGM_N. {ECO:0000259|Pfam:PF06535}.
FT   NON_TER      90     90       {ECO:0000313|Ensembl:ENSP00000451709}.
SQ   SEQUENCE   90 AA;  9559 MW;  2FAA94FB2052B88E CRC64;
     MGMGRGAGRS ALGFWPTLAF LLCSFPAATS PCKILKCNSE FWSATSGSHA PASDDTPEFC
     AALRSYALCT RRTARTCRGD LAYHSAVHGI
//