ID   G3V3Y2_HUMAN            Unreviewed;        91 AA.
AC   G3V3Y2;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   16-JAN-2019, entry version 47.
DE   SubName: Full=Fibulin-5 {ECO:0000313|Ensembl:ENSP00000451486};
DE   Flags: Fragment;
GN   Name=FBLN5 {ECO:0000313|Ensembl:ENSP00000451486};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000451486, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000451486, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12508121; DOI=10.1038/nature01348;
RA   Heilig R., Eckenberg R., Petit J.-L., Fonknechten N., Da Silva C.,
RA   Cattolico L., Levy M., Barbe V., De Berardinis V., Ureta-Vidal A.,
RA   Pelletier E., Vico V., Anthouard V., Rowen L., Madan A., Qin S.,
RA   Sun H., Du H., Pepin K., Artiguenave F., Robert C., Cruaud C.,
RA   Bruels T., Jaillon O., Friedlander L., Samson G., Brottier P.,
RA   Cure S., Segurens B., Aniere F., Samain S., Crespeau H., Abbasi N.,
RA   Aiach N., Boscus D., Dickhoff R., Dors M., Dubois I., Friedman C.,
RA   Gouyvenoux M., James R., Madan A., Mairey-Estrada B., Mangenot S.,
RA   Martins N., Menard M., Oztas S., Ratcliffe A., Shaffer T., Trask B.,
RA   Vacherie B., Bellemere C., Belser C., Besnard-Gonnet M.,
RA   Bartol-Mavel D., Boutard M., Briez-Silla S., Combette S.,
RA   Dufosse-Laurent V., Ferron C., Lechaplais C., Louesse C., Muselet D.,
RA   Magdelenat G., Pateau E., Petit E., Sirvain-Trukniewicz P., Trybou A.,
RA   Vega-Czarny N., Bataille E., Bluet E., Bordelais I., Dubois M.,
RA   Dumont C., Guerin T., Haffray S., Hammadi R., Muanga J., Pellouin V.,
RA   Robert D., Wunderle E., Gauguet G., Roy A., Sainte-Marthe L.,
RA   Verdier J., Verdier-Discala C., Hillier L.W., Fulton L., McPherson J.,
RA   Matsuda F., Wilson R., Scarpelli C., Gyapay G., Wincker P., Saurin W.,
RA   Quetier F., Waterston R., Hood L., Weissenbach J.;
RT   "The DNA sequence and analysis of human chromosome 14.";
RL   Nature 421:601-607(2003).
RN   [2] {ECO:0000313|Ensembl:ENSP00000451486}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2011) to UniProtKB.
RN   [3] {ECO:0000213|PubMed:24275569}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=24275569; DOI=10.1016/j.jprot.2013.11.014;
RA   Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D.,
RA   Wang L., Ye M., Zou H.;
RT   "An enzyme assisted RP-RPLC approach for in-depth analysis of human
RT   liver phosphoproteome.";
RL   J. Proteomics 96:253-262(2014).
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DR   EMBL; AL049872; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AL590328; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF455988; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; G3V3Y2; -.
DR   jPOST; G3V3Y2; -.
DR   PeptideAtlas; G3V3Y2; -.
DR   PRIDE; G3V3Y2; -.
DR   Ensembl; ENST00000554468; ENSP00000451486; ENSG00000140092.
DR   UCSC; uc059ekr.1; human.
DR   EuPathDB; HostDB:ENSG00000140092.14; -.
DR   HGNC; HGNC:3602; FBLN5.
DR   OpenTargets; ENSG00000140092; -.
DR   eggNOG; ENOG410IR76; Eukaryota.
DR   eggNOG; ENOG41104WD; LUCA.
DR   GeneTree; ENSGT00940000158774; -.
DR   Proteomes; UP000005640; Chromosome 14.
DR   Bgee; ENSG00000140092; Expressed in 199 organ(s), highest expression level in thoracic aorta.
DR   ExpressionAtlas; G3V3Y2; baseline and differential.
DR   GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0048251; P:elastic fiber assembly; IEA:InterPro.
DR   InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR   InterPro; IPR018097; EGF_Ca-bd_CS.
DR   InterPro; IPR037288; Fibulin-5.
DR   InterPro; IPR037287; Fibulin_3/4/5.
DR   PANTHER; PTHR44074; PTHR44074; 1.
DR   PANTHER; PTHR44074:SF4; PTHR44074:SF4; 1.
DR   Pfam; PF07645; EGF_CA; 1.
DR   PROSITE; PS01187; EGF_CA; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:G3V3Y2,
KW   ECO:0000213|PeptideAtlas:G3V3Y2};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     23       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        24     91       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003457293.
FT   DOMAIN       42     69       EGF_CA. {ECO:0000259|Pfam:PF07645}.
FT   NON_TER      91     91       {ECO:0000313|Ensembl:ENSP00000451486}.
SQ   SEQUENCE   91 AA;  9900 MW;  08EDB08785677D6E CRC64;
     MPGIKRILTV TILALCLPSP GNAQAQCTNG FDLDRQSGQC LDIDECRTIP EACRGDMMCV
     NQNGGYLCIP RTNPVYRGPY SNPYSTPYSG P
//