ID   G3V3W8_HUMAN            Unreviewed;       136 AA.
AC   G3V3W8;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   16-JAN-2019, entry version 43.
DE   SubName: Full=Probable ribonuclease 11 {ECO:0000313|Ensembl:ENSP00000451466};
DE   Flags: Fragment;
GN   Name=RNASE11 {ECO:0000313|Ensembl:ENSP00000451466};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000451466, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000451466, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12508121; DOI=10.1038/nature01348;
RA   Heilig R., Eckenberg R., Petit J.-L., Fonknechten N., Da Silva C.,
RA   Cattolico L., Levy M., Barbe V., De Berardinis V., Ureta-Vidal A.,
RA   Pelletier E., Vico V., Anthouard V., Rowen L., Madan A., Qin S.,
RA   Sun H., Du H., Pepin K., Artiguenave F., Robert C., Cruaud C.,
RA   Bruels T., Jaillon O., Friedlander L., Samson G., Brottier P.,
RA   Cure S., Segurens B., Aniere F., Samain S., Crespeau H., Abbasi N.,
RA   Aiach N., Boscus D., Dickhoff R., Dors M., Dubois I., Friedman C.,
RA   Gouyvenoux M., James R., Madan A., Mairey-Estrada B., Mangenot S.,
RA   Martins N., Menard M., Oztas S., Ratcliffe A., Shaffer T., Trask B.,
RA   Vacherie B., Bellemere C., Belser C., Besnard-Gonnet M.,
RA   Bartol-Mavel D., Boutard M., Briez-Silla S., Combette S.,
RA   Dufosse-Laurent V., Ferron C., Lechaplais C., Louesse C., Muselet D.,
RA   Magdelenat G., Pateau E., Petit E., Sirvain-Trukniewicz P., Trybou A.,
RA   Vega-Czarny N., Bataille E., Bluet E., Bordelais I., Dubois M.,
RA   Dumont C., Guerin T., Haffray S., Hammadi R., Muanga J., Pellouin V.,
RA   Robert D., Wunderle E., Gauguet G., Roy A., Sainte-Marthe L.,
RA   Verdier J., Verdier-Discala C., Hillier L.W., Fulton L., McPherson J.,
RA   Matsuda F., Wilson R., Scarpelli C., Gyapay G., Wincker P., Saurin W.,
RA   Quetier F., Waterston R., Hood L., Weissenbach J.;
RT   "The DNA sequence and analysis of human chromosome 14.";
RL   Nature 421:601-607(2003).
RN   [2] {ECO:0000313|Ensembl:ENSP00000451466}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2011) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the pancreatic ribonuclease family.
CC       {ECO:0000256|SAAS:SAAS00686975}.
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DR   EMBL; AL163195; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; G3V3W8; -.
DR   jPOST; G3V3W8; -.
DR   PRIDE; G3V3W8; -.
DR   Ensembl; ENST00000554842; ENSP00000451466; ENSG00000173464.
DR   UCSC; uc058yup.1; human.
DR   EuPathDB; HostDB:ENSG00000173464.14; -.
DR   HGNC; HGNC:19269; RNASE11.
DR   eggNOG; ENOG410IY14; Eukaryota.
DR   eggNOG; ENOG4111CPE; LUCA.
DR   GeneTree; ENSGT00510000049471; -.
DR   Proteomes; UP000005640; Chromosome 14.
DR   Bgee; ENSG00000173464; Expressed in 28 organ(s), highest expression level in right testis.
DR   ExpressionAtlas; G3V3W8; baseline.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   Gene3D; 3.10.130.10; -; 1.
DR   InterPro; IPR029743; RNASE11.
DR   InterPro; IPR001427; RNaseA.
DR   InterPro; IPR036816; RNaseA-like_dom_sf.
DR   PANTHER; PTHR11437; PTHR11437; 1.
DR   PANTHER; PTHR11437:SF22; PTHR11437:SF22; 1.
DR   SUPFAM; SSF54076; SSF54076; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     18       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        19    136       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003456755.
FT   NON_TER     136    136       {ECO:0000313|Ensembl:ENSP00000451466}.
SQ   SEQUENCE   136 AA;  15420 MW;  5178B7AFCD099F7C CRC64;
     METFPLLLLS LGLVLAEASE STMKIIKEEF TDEEMQYDMA KSGQEKQTIE ILMNPILLVK
     NTSLSMSKDD MSSTLLTFRS LHYNDPKGNS SGNDKECCND MTVWRKVSEA NGSCKWSNNF
     IRSSTEVMRR VHRAPS
//