ID   G3V3B3_HUMAN            Unreviewed;       163 AA.
AC   G3V3B3;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   16-JAN-2019, entry version 45.
DE   SubName: Full=Protein sel-1 homolog 1 {ECO:0000313|Ensembl:ENSP00000451144};
DE   Flags: Fragment;
GN   Name=SEL1L {ECO:0000313|Ensembl:ENSP00000451144};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000451144, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000451144, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12508121; DOI=10.1038/nature01348;
RA   Heilig R., Eckenberg R., Petit J.-L., Fonknechten N., Da Silva C.,
RA   Cattolico L., Levy M., Barbe V., De Berardinis V., Ureta-Vidal A.,
RA   Pelletier E., Vico V., Anthouard V., Rowen L., Madan A., Qin S.,
RA   Sun H., Du H., Pepin K., Artiguenave F., Robert C., Cruaud C.,
RA   Bruels T., Jaillon O., Friedlander L., Samson G., Brottier P.,
RA   Cure S., Segurens B., Aniere F., Samain S., Crespeau H., Abbasi N.,
RA   Aiach N., Boscus D., Dickhoff R., Dors M., Dubois I., Friedman C.,
RA   Gouyvenoux M., James R., Madan A., Mairey-Estrada B., Mangenot S.,
RA   Martins N., Menard M., Oztas S., Ratcliffe A., Shaffer T., Trask B.,
RA   Vacherie B., Bellemere C., Belser C., Besnard-Gonnet M.,
RA   Bartol-Mavel D., Boutard M., Briez-Silla S., Combette S.,
RA   Dufosse-Laurent V., Ferron C., Lechaplais C., Louesse C., Muselet D.,
RA   Magdelenat G., Pateau E., Petit E., Sirvain-Trukniewicz P., Trybou A.,
RA   Vega-Czarny N., Bataille E., Bluet E., Bordelais I., Dubois M.,
RA   Dumont C., Guerin T., Haffray S., Hammadi R., Muanga J., Pellouin V.,
RA   Robert D., Wunderle E., Gauguet G., Roy A., Sainte-Marthe L.,
RA   Verdier J., Verdier-Discala C., Hillier L.W., Fulton L., McPherson J.,
RA   Matsuda F., Wilson R., Scarpelli C., Gyapay G., Wincker P., Saurin W.,
RA   Quetier F., Waterston R., Hood L., Weissenbach J.;
RT   "The DNA sequence and analysis of human chromosome 14.";
RL   Nature 421:601-607(2003).
RN   [2] {ECO:0000213|PubMed:21269460}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA   Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P.,
RA   Burckstummer T., Bennett K.L., Superti-Furga G., Colinge J.;
RT   "Initial characterization of the human central proteome.";
RL   BMC Syst. Biol. 5:17-17(2011).
RN   [3] {ECO:0000313|Ensembl:ENSP00000451144}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2011) to UniProtKB.
RN   [4] {ECO:0000213|PubMed:24275569}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=24275569; DOI=10.1016/j.jprot.2013.11.014;
RA   Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D.,
RA   Wang L., Ye M., Zou H.;
RT   "An enzyme assisted RP-RPLC approach for in-depth analysis of human
RT   liver phosphoproteome.";
RL   J. Proteomics 96:253-262(2014).
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DR   EMBL; AL121769; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AL136039; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; G3V3B3; -.
DR   jPOST; G3V3B3; -.
DR   MaxQB; G3V3B3; -.
DR   PeptideAtlas; G3V3B3; -.
DR   PRIDE; G3V3B3; -.
DR   Ensembl; ENST00000557372; ENSP00000451144; ENSG00000071537.
DR   UCSC; uc059dys.1; human.
DR   EuPathDB; HostDB:ENSG00000071537.13; -.
DR   HGNC; HGNC:10717; SEL1L.
DR   OpenTargets; ENSG00000071537; -.
DR   GeneTree; ENSGT00940000156671; -.
DR   ChiTaRS; SEL1L; human.
DR   Proteomes; UP000005640; Chromosome 14.
DR   Bgee; ENSG00000071537; Expressed in 241 organ(s), highest expression level in duodenum.
DR   ExpressionAtlas; G3V3B3; baseline and differential.
DR   CDD; cd00062; FN2; 1.
DR   Gene3D; 2.10.10.10; -; 1.
DR   InterPro; IPR000562; FN_type2_dom.
DR   InterPro; IPR036943; FN_type2_sf.
DR   InterPro; IPR013806; Kringle-like.
DR   Pfam; PF00040; fn2; 1.
DR   SMART; SM00059; FN2; 1.
DR   SUPFAM; SSF57440; SSF57440; 1.
DR   PROSITE; PS51092; FN2_2; 1.
PE   1: Evidence at protein level;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00479,
KW   ECO:0000256|SAAS:SAAS00793910};
KW   Proteomics identification {ECO:0000213|EPD:G3V3B3,
KW   ECO:0000213|MaxQB:G3V3B3, ECO:0000213|PeptideAtlas:G3V3B3};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Repeat {ECO:0000256|SAAS:SAAS00793883};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     21       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        22    163       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003457124.
FT   DOMAIN      101    149       Fibronectin type-II.
FT                                {ECO:0000259|PROSITE:PS51092}.
FT   COILED       65     85       {ECO:0000256|SAM:Coils}.
FT   DISULFID    106    132       {ECO:0000256|PROSITE-ProRule:PRU00479}.
FT   DISULFID    120    147       {ECO:0000256|PROSITE-ProRule:PRU00479}.
FT   NON_TER     163    163       {ECO:0000313|Ensembl:ENSP00000451144}.
SQ   SEQUENCE   163 AA;  18348 MW;  3F904BCFA101C08E CRC64;
     MRVRIGLTLL LCAVLLSLAS ASSDEEGSQD ESLDSKTTLT SDESVKDHTT AGRVVAGQIF
     LDSEESELES SIQEEEDSLK SQEGESVTED ISFLESPNPE NKDYEEPKKV RKPDKEYDEC
     TSDGREDGRL WCATTYDYKA DEKWGFCETE EEAAKRRQMQ EAE
//