ID   G3V373_HUMAN            Unreviewed;       105 AA.
AC   G3V373;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   16-JAN-2019, entry version 38.
DE   SubName: Full=Gamma-aminobutyric acid receptor subunit beta-3 {ECO:0000313|Ensembl:ENSP00000451077};
GN   Name=GABRB3 {ECO:0000313|Ensembl:ENSP00000451077};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000451077, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000451077, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16572171; DOI=10.1038/nature04601;
RA   Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K.,
RA   Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K.,
RA   FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N.,
RA   Abouelleil A., Arachchi H.M., Baradarani L., Birditt B., Bloom S.,
RA   Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K.,
RA   DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R.,
RA   Fahey J., Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G.,
RA   Johnson E., Jones C., Kamat A., Kaur A., Locke D.P., Madan A.,
RA   Munson G., Jaffe D.B., Lui A., Macdonald P., Mauceli E., Naylor J.W.,
RA   Nesbitt R., Nicol R., O'Leary S.B., Ratcliffe A., Rounsley S., She X.,
RA   Sneddon K.M., Stewart S., Sougnez C., Stone S.M., Topham K.,
RA   Vincent D., Wang S., Zimmer A.R., Birren B.W., Hood L., Lander E.S.,
RA   Nusbaum C.;
RT   "Analysis of the DNA sequence and duplication history of human
RT   chromosome 15.";
RL   Nature 440:671-675(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000451077}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2011) to UniProtKB.
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DR   EMBL; AC009878; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC011196; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC104569; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC127511; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC135999; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC145167; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC145196; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; EU606048; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KC877539; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; G3V373; -.
DR   jPOST; G3V373; -.
DR   Ensembl; ENST00000554556; ENSP00000451077; ENSG00000166206.
DR   UCSC; uc059gxe.1; human.
DR   EuPathDB; HostDB:ENSG00000166206.13; -.
DR   HGNC; HGNC:4083; GABRB3.
DR   OpenTargets; ENSG00000166206; -.
DR   GeneTree; ENSGT00940000154713; -.
DR   ChiTaRS; GABRB3; human.
DR   Proteomes; UP000005640; Chromosome 15.
DR   Bgee; ENSG00000166206; Expressed in 156 organ(s), highest expression level in pituitary gland.
DR   ExpressionAtlas; G3V373; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:InterPro.
DR   GO; GO:0005230; F:extracellular ligand-gated ion channel activity; IEA:InterPro.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   Gene3D; 2.70.170.10; -; 1.
DR   InterPro; IPR036734; Neur_chan_lig-bd_sf.
DR   InterPro; IPR006201; Neur_channel.
DR   PANTHER; PTHR18945; PTHR18945; 1.
DR   SUPFAM; SSF63712; SSF63712; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     25       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        26    105       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003456748.
SQ   SEQUENCE   105 AA;  11236 MW;  483E08B6571D688D CRC64;
     MWGLAGGRLF GIFSAPVLVA VVCCAQSVND PGNMSFVKET VDKLLKGYDI RLRPDFGGPP
     VCVGMNIDIA SIDMVSEVNM NHHDSSMHDG PQEIPPGRAE LHSGN
//