ID   G3V2Y2_HUMAN            Unreviewed;        81 AA.
AC   G3V2Y2;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 8.
DT   16-JAN-2019, entry version 50.
DE   SubName: Full=Transmembrane emp24 domain-containing protein 7 {ECO:0000313|Ensembl:ENSP00000450928};
DE   Flags: Fragment;
GN   Name=TMED7 {ECO:0000313|Ensembl:ENSP00000450928};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000450928, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000450928, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15372022; DOI=10.1038/nature02919;
RA   Schmutz J., Martin J., Terry A., Couronne O., Grimwood J., Lowry S.,
RA   Gordon L.A., Scott D., Xie G., Huang W., Hellsten U., Tran-Gyamfi M.,
RA   She X., Prabhakar S., Aerts A., Altherr M., Bajorek E., Black S.,
RA   Branscomb E., Caoile C., Challacombe J.F., Chan Y.M., Denys M.,
RA   Detter J.C., Escobar J., Flowers D., Fotopulos D., Glavina T.,
RA   Gomez M., Gonzales E., Goodstein D., Grigoriev I., Groza M.,
RA   Hammon N., Hawkins T., Haydu L., Israni S., Jett J., Kadner K.,
RA   Kimball H., Kobayashi A., Lopez F., Lou Y., Martinez D., Medina C.,
RA   Morgan J., Nandkeshwar R., Noonan J.P., Pitluck S., Pollard M.,
RA   Predki P., Priest J., Ramirez L., Retterer J., Rodriguez A.,
RA   Rogers S., Salamov A., Salazar A., Thayer N., Tice H., Tsai M.,
RA   Ustaszewska A., Vo N., Wheeler J., Wu K., Yang J., Dickson M.,
RA   Cheng J.-F., Eichler E.E., Olsen A., Pennacchio L.A., Rokhsar D.S.,
RA   Richardson P., Lucas S.M., Myers R.M., Rubin E.M.;
RT   "The DNA sequence and comparative analysis of human chromosome 5.";
RL   Nature 431:268-274(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000450928}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2011) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003827};
CC       Single-pass type I membrane protein
CC       {ECO:0000256|RuleBase:RU003827}.
CC   -!- SIMILARITY: Belongs to the EMP24/GP25L family.
CC       {ECO:0000256|RuleBase:RU003827}.
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DR   EMBL; AC010226; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   jPOST; G3V2Y2; -.
DR   PeptideAtlas; G3V2Y2; -.
DR   PRIDE; G3V2Y2; -.
DR   Ensembl; ENST00000508420; ENSP00000450928; ENSG00000134970.
DR   UCSC; uc063gdk.1; human.
DR   EuPathDB; HostDB:ENSG00000134970.13; -.
DR   HGNC; HGNC:24253; TMED7.
DR   OpenTargets; ENSG00000134970; -.
DR   eggNOG; KOG1693; Eukaryota.
DR   eggNOG; ENOG4111JPD; LUCA.
DR   GeneTree; ENSGT00940000158463; -.
DR   Proteomes; UP000005640; Chromosome 5.
DR   Bgee; ENSG00000134970; Expressed in 239 organ(s), highest expression level in oviduct epithelium.
DR   ExpressionAtlas; G3V2Y2; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR009038; GOLD_dom.
DR   InterPro; IPR036598; GOLD_dom_sf.
DR   InterPro; IPR015718; TMED7.
DR   InterPro; IPR015720; TMP21-related.
DR   PANTHER; PTHR22811; PTHR22811; 1.
DR   PANTHER; PTHR22811:SF49; PTHR22811:SF49; 1.
DR   Pfam; PF01105; EMP24_GP25L; 1.
DR   SUPFAM; SSF101576; SSF101576; 1.
DR   PROSITE; PS50866; GOLD; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Membrane {ECO:0000256|RuleBase:RU003827};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|RuleBase:RU003827}.
FT   SIGNAL        1     34       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        35     81       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5008414731.
FT   DOMAIN       46     81       GOLD. {ECO:0000259|PROSITE:PS50866}.
FT   NON_TER      81     81       {ECO:0000313|Ensembl:ENSP00000450928}.
SQ   SEQUENCE   81 AA;  8837 MW;  8E1B9B6C8F58795D CRC64;
     MPRPGSAQRW AAVAGRWGCR LLALLLLVPG PGGASEITFE LPDNAKQCFY EDIAQGTKCT
     LEFQVITGGH YDVDCRLEDP D
//