ID   G3V2T4_HUMAN            Unreviewed;       135 AA.
AC   G3V2T4;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   16-JAN-2019, entry version 37.
DE   SubName: Full=Legumain {ECO:0000313|Ensembl:ENSP00000450854};
DE   Flags: Fragment;
GN   Name=LGMN {ECO:0000313|Ensembl:ENSP00000450854};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000450854, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000450854, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12508121; DOI=10.1038/nature01348;
RA   Heilig R., Eckenberg R., Petit J.-L., Fonknechten N., Da Silva C.,
RA   Cattolico L., Levy M., Barbe V., De Berardinis V., Ureta-Vidal A.,
RA   Pelletier E., Vico V., Anthouard V., Rowen L., Madan A., Qin S.,
RA   Sun H., Du H., Pepin K., Artiguenave F., Robert C., Cruaud C.,
RA   Bruels T., Jaillon O., Friedlander L., Samson G., Brottier P.,
RA   Cure S., Segurens B., Aniere F., Samain S., Crespeau H., Abbasi N.,
RA   Aiach N., Boscus D., Dickhoff R., Dors M., Dubois I., Friedman C.,
RA   Gouyvenoux M., James R., Madan A., Mairey-Estrada B., Mangenot S.,
RA   Martins N., Menard M., Oztas S., Ratcliffe A., Shaffer T., Trask B.,
RA   Vacherie B., Bellemere C., Belser C., Besnard-Gonnet M.,
RA   Bartol-Mavel D., Boutard M., Briez-Silla S., Combette S.,
RA   Dufosse-Laurent V., Ferron C., Lechaplais C., Louesse C., Muselet D.,
RA   Magdelenat G., Pateau E., Petit E., Sirvain-Trukniewicz P., Trybou A.,
RA   Vega-Czarny N., Bataille E., Bluet E., Bordelais I., Dubois M.,
RA   Dumont C., Guerin T., Haffray S., Hammadi R., Muanga J., Pellouin V.,
RA   Robert D., Wunderle E., Gauguet G., Roy A., Sainte-Marthe L.,
RA   Verdier J., Verdier-Discala C., Hillier L.W., Fulton L., McPherson J.,
RA   Matsuda F., Wilson R., Scarpelli C., Gyapay G., Wincker P., Saurin W.,
RA   Quetier F., Waterston R., Hood L., Weissenbach J.;
RT   "The DNA sequence and analysis of human chromosome 14.";
RL   Nature 421:601-607(2003).
RN   [2] {ECO:0000213|PubMed:21269460}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA   Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P.,
RA   Burckstummer T., Bennett K.L., Superti-Furga G., Colinge J.;
RT   "Initial characterization of the human central proteome.";
RL   BMC Syst. Biol. 5:17-17(2011).
RN   [3] {ECO:0000313|Ensembl:ENSP00000450854}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2011) to UniProtKB.
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DR   EMBL; AL132987; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AL136332; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; G3V2T4; -.
DR   EPD; G3V2T4; -.
DR   jPOST; G3V2T4; -.
DR   MaxQB; G3V2T4; -.
DR   PeptideAtlas; G3V2T4; -.
DR   PRIDE; G3V2T4; -.
DR   Ensembl; ENST00000553802; ENSP00000450854; ENSG00000100600.
DR   UCSC; uc059eny.1; human.
DR   EuPathDB; HostDB:ENSG00000100600.14; -.
DR   HGNC; HGNC:9472; LGMN.
DR   OpenTargets; ENSG00000100600; -.
DR   GeneTree; ENSGT00940000154782; -.
DR   ChiTaRS; LGMN; human.
DR   Proteomes; UP000005640; Chromosome 14.
DR   Bgee; ENSG00000100600; Expressed in 231 organ(s), highest expression level in synovial joint.
DR   ExpressionAtlas; G3V2T4; baseline and differential.
DR   GO; GO:0008233; F:peptidase activity; IEA:InterPro.
DR   InterPro; IPR001096; Peptidase_C13.
DR   PANTHER; PTHR12000; PTHR12000; 1.
DR   Pfam; PF01650; Peptidase_C13; 1.
DR   PRINTS; PR00776; HEMOGLOBNASE.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|EPD:G3V2T4,
KW   ECO:0000213|MaxQB:G3V2T4, ECO:0000213|PeptideAtlas:G3V2T4};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     17       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        18    135       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003457111.
FT   NON_TER     135    135       {ECO:0000313|Ensembl:ENSP00000450854}.
SQ   SEQUENCE   135 AA;  14636 MW;  344418898A54DDEA CRC64;
     MVWKVAVFLS VALGIGAVPI DDPEDGGKHW VVIVAGSNGW YNYRHQADAC HAYQIIHRNG
     IPDEQIVVMI NPTPGIVINR PNGTDVYQGV PKDYTGEDVT PQNFLAVLRG DAEAVKGIGS
     GKVLKSGPQD HVFIY
//