ID   G3V2G6_HUMAN            Unreviewed;       178 AA.
AC   G3V2G6;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   16-JAN-2019, entry version 45.
DE   SubName: Full=Retinol dehydrogenase 11 {ECO:0000313|Ensembl:ENSP00000450651};
DE   Flags: Fragment;
GN   Name=RDH11 {ECO:0000313|Ensembl:ENSP00000450651};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000450651, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000450651, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12508121; DOI=10.1038/nature01348;
RA   Heilig R., Eckenberg R., Petit J.-L., Fonknechten N., Da Silva C.,
RA   Cattolico L., Levy M., Barbe V., De Berardinis V., Ureta-Vidal A.,
RA   Pelletier E., Vico V., Anthouard V., Rowen L., Madan A., Qin S.,
RA   Sun H., Du H., Pepin K., Artiguenave F., Robert C., Cruaud C.,
RA   Bruels T., Jaillon O., Friedlander L., Samson G., Brottier P.,
RA   Cure S., Segurens B., Aniere F., Samain S., Crespeau H., Abbasi N.,
RA   Aiach N., Boscus D., Dickhoff R., Dors M., Dubois I., Friedman C.,
RA   Gouyvenoux M., James R., Madan A., Mairey-Estrada B., Mangenot S.,
RA   Martins N., Menard M., Oztas S., Ratcliffe A., Shaffer T., Trask B.,
RA   Vacherie B., Bellemere C., Belser C., Besnard-Gonnet M.,
RA   Bartol-Mavel D., Boutard M., Briez-Silla S., Combette S.,
RA   Dufosse-Laurent V., Ferron C., Lechaplais C., Louesse C., Muselet D.,
RA   Magdelenat G., Pateau E., Petit E., Sirvain-Trukniewicz P., Trybou A.,
RA   Vega-Czarny N., Bataille E., Bluet E., Bordelais I., Dubois M.,
RA   Dumont C., Guerin T., Haffray S., Hammadi R., Muanga J., Pellouin V.,
RA   Robert D., Wunderle E., Gauguet G., Roy A., Sainte-Marthe L.,
RA   Verdier J., Verdier-Discala C., Hillier L.W., Fulton L., McPherson J.,
RA   Matsuda F., Wilson R., Scarpelli C., Gyapay G., Wincker P., Saurin W.,
RA   Quetier F., Waterston R., Hood L., Weissenbach J.;
RT   "The DNA sequence and analysis of human chromosome 14.";
RL   Nature 421:601-607(2003).
RN   [2] {ECO:0000213|PubMed:21269460}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA   Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P.,
RA   Burckstummer T., Bennett K.L., Superti-Furga G., Colinge J.;
RT   "Initial characterization of the human central proteome.";
RL   BMC Syst. Biol. 5:17-17(2011).
RN   [3] {ECO:0000313|Ensembl:ENSP00000450651}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2011) to UniProtKB.
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DR   EMBL; AL049779; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; G3V2G6; -.
DR   EPD; G3V2G6; -.
DR   jPOST; G3V2G6; -.
DR   MaxQB; G3V2G6; -.
DR   PeptideAtlas; G3V2G6; -.
DR   PRIDE; G3V2G6; -.
DR   Ensembl; ENST00000557273; ENSP00000450651; ENSG00000072042.
DR   UCSC; uc059cri.1; human.
DR   EuPathDB; HostDB:ENSG00000072042.12; -.
DR   HGNC; HGNC:17964; RDH11.
DR   OpenTargets; ENSG00000072042; -.
DR   eggNOG; KOG1208; Eukaryota.
DR   eggNOG; COG1028; LUCA.
DR   GeneTree; ENSGT00940000158191; -.
DR   ChiTaRS; RDH11; human.
DR   Proteomes; UP000005640; Chromosome 14.
DR   Bgee; ENSG00000072042; Expressed in 236 organ(s), highest expression level in pigmented layer of retina.
DR   ExpressionAtlas; G3V2G6; baseline and differential.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR002347; SDR_fam.
DR   Pfam; PF00106; adh_short; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|EPD:G3V2G6,
KW   ECO:0000213|MaxQB:G3V2G6, ECO:0000213|PeptideAtlas:G3V2G6};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     20       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        21    178       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003457329.
FT   NON_TER     178    178       {ECO:0000313|Ensembl:ENSP00000450651}.
SQ   SEQUENCE   178 AA;  19959 MW;  54FEFD2AC786991A CRC64;
     MVELMFPLLL LLLPFLLYMA APQIRKMLSS GVCTSTVQLP GKVVVVTGAN TGIGKETAKE
     LAQRGHFLLT HLLLEKLKES APSRIVNVSS LAHHLGRIHF HNLQGEKFYN AGLAYCHSKL
     ANILFTQELA RRLKGSGVTT YSVHPGTVQS ELVRHSSFMR WMWWLFSFFI KTPQQGAQ
//