ID   G3V2A7_HUMAN            Unreviewed;        56 AA.
AC   G3V2A7;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   05-DEC-2018, entry version 28.
DE   SubName: Full=Type II iodothyronine deiodinase {ECO:0000313|Ensembl:ENSP00000450547};
GN   Name=DIO2 {ECO:0000313|Ensembl:ENSP00000450547};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000450547, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000450547, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12508121; DOI=10.1038/nature01348;
RA   Heilig R., Eckenberg R., Petit J.-L., Fonknechten N., Da Silva C.,
RA   Cattolico L., Levy M., Barbe V., De Berardinis V., Ureta-Vidal A.,
RA   Pelletier E., Vico V., Anthouard V., Rowen L., Madan A., Qin S.,
RA   Sun H., Du H., Pepin K., Artiguenave F., Robert C., Cruaud C.,
RA   Bruels T., Jaillon O., Friedlander L., Samson G., Brottier P.,
RA   Cure S., Segurens B., Aniere F., Samain S., Crespeau H., Abbasi N.,
RA   Aiach N., Boscus D., Dickhoff R., Dors M., Dubois I., Friedman C.,
RA   Gouyvenoux M., James R., Madan A., Mairey-Estrada B., Mangenot S.,
RA   Martins N., Menard M., Oztas S., Ratcliffe A., Shaffer T., Trask B.,
RA   Vacherie B., Bellemere C., Belser C., Besnard-Gonnet M.,
RA   Bartol-Mavel D., Boutard M., Briez-Silla S., Combette S.,
RA   Dufosse-Laurent V., Ferron C., Lechaplais C., Louesse C., Muselet D.,
RA   Magdelenat G., Pateau E., Petit E., Sirvain-Trukniewicz P., Trybou A.,
RA   Vega-Czarny N., Bataille E., Bluet E., Bordelais I., Dubois M.,
RA   Dumont C., Guerin T., Haffray S., Hammadi R., Muanga J., Pellouin V.,
RA   Robert D., Wunderle E., Gauguet G., Roy A., Sainte-Marthe L.,
RA   Verdier J., Verdier-Discala C., Hillier L.W., Fulton L., McPherson J.,
RA   Matsuda F., Wilson R., Scarpelli C., Gyapay G., Wincker P., Saurin W.,
RA   Quetier F., Waterston R., Hood L., Weissenbach J.;
RT   "The DNA sequence and analysis of human chromosome 14.";
RL   Nature 421:601-607(2003).
RN   [2] {ECO:0000313|Ensembl:ENSP00000450547}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2011) to UniProtKB.
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DR   EMBL; AC007372; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC010849; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AL049837; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   PRIDE; G3V2A7; -.
DR   Ensembl; ENST00000557125; ENSP00000450547; ENSG00000211448.
DR   UCSC; uc059dxf.1; human.
DR   EuPathDB; HostDB:ENSG00000211448.11; -.
DR   HGNC; HGNC:2884; DIO2.
DR   OpenTargets; ENSG00000211448; -.
DR   GeneTree; ENSGT00940000154482; -.
DR   ChiTaRS; DIO2; human.
DR   Proteomes; UP000005640; Chromosome 14.
DR   Bgee; ENSG00000211448; Expressed in 192 organ(s), highest expression level in uterine cervix.
DR   ExpressionAtlas; G3V2A7; baseline and differential.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     21       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        22     56       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003456971.
SQ   SEQUENCE   56 AA;  6455 MW;  780A4F4EEE4A5E07 CRC64;
     MGILSVDLLI TLQILPPSAN WWKSSPQWLT SCWSTLMRLI HQMAGRYRGT PLCLLR
//