ID F8WFC4_HUMAN Unreviewed; 95 AA. AC F8WFC4; DT 21-SEP-2011, integrated into UniProtKB/TrEMBL. DT 21-SEP-2011, sequence version 1. DT 12-SEP-2018, entry version 49. DE SubName: Full=Myelin protein zero-like protein 1 {ECO:0000313|Ensembl:ENSP00000399490}; GN Name=MPZL1 {ECO:0000313|Ensembl:ENSP00000399490}; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000399490, ECO:0000313|Proteomes:UP000005640}; RN [1] {ECO:0000313|Ensembl:ENSP00000399490, ECO:0000313|Proteomes:UP000005640} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=16710414; DOI=10.1038/nature04727; RA Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., RA Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C., RA Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., RA McDonald L., Evans R., Phillips K., Atkinson A., Cooper R., Jones C., RA Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., RA Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I., Aubin K., RA Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., RA Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., RA Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., RA Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., RA Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., RA Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., RA Ghori M.R., Gibson R., Gilby L.M., Gillett W., Glithero R.J., RA Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., RA Hammond S., Harrison E.S., Hart E., Haugen E., Heath P.D., Holmes S., RA Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., RA James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., RA Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., RA Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., RA Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., RA Matthews N.S., McLaren S., Milne S., Mistry S., Moore M.J., RA Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., RA Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., RA Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., RA Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., RA Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., RA Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., RA Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., RA Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R., RA Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., RA Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R., Banerjee R., RA Bryant S.P., Burford D.C., Burrill W.D., Clegg S.M., Dhami P., RA Dovey O., Faulkner L.M., Gribble S.M., Langford C.F., Pandian R.D., RA Porter K.M., Prigmore E.; RT "The DNA sequence and biological annotation of human chromosome 1."; RL Nature 441:315-321(2006). RN [2] {ECO:0000313|Ensembl:ENSP00000399490} RP IDENTIFICATION. RG Ensembl; RL Submitted (JUL-2011) to UniProtKB. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC ----------------------------------------------------------------------- DR EMBL; AL356532; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; KF455055; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; Z99943; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR ProteinModelPortal; F8WFC4; -. DR MaxQB; F8WFC4; -. DR PeptideAtlas; F8WFC4; -. DR Ensembl; ENST00000448405; ENSP00000399490; ENSG00000197965. DR UCSC; uc057ncc.1; human. DR EuPathDB; HostDB:ENSG00000197965.11; -. DR HGNC; HGNC:7226; MPZL1. DR OpenTargets; ENSG00000197965; -. DR eggNOG; ENOG410IVXC; Eukaryota. DR eggNOG; ENOG4111MDZ; LUCA. DR GeneTree; ENSGT00900000140913; -. DR ChiTaRS; MPZL1; human. DR Proteomes; UP000005640; Chromosome 1. DR Bgee; ENSG00000197965; Expressed in 219 organ(s), highest expression level in urinary bladder. DR ExpressionAtlas; F8WFC4; baseline and differential. DR GO; GO:0005887; C:integral component of plasma membrane; IEA:InterPro. DR GO; GO:0007165; P:signal transduction; IEA:InterPro. DR Gene3D; 2.60.40.10; -; 1. DR InterPro; IPR013783; Ig-like_fold. DR InterPro; IPR013106; Ig_V-set. DR InterPro; IPR029870; MPZL1. DR InterPro; IPR000920; Myelin_P0-rel. DR PANTHER; PTHR13869; PTHR13869; 1. DR PANTHER; PTHR13869:SF19; PTHR13869:SF19; 1. DR Pfam; PF07686; V-set; 1. PE 1: Evidence at protein level; KW Complete proteome {ECO:0000313|Proteomes:UP000005640}; KW Proteomics identification {ECO:0000213|MaxQB:F8WFC4, KW ECO:0000213|PeptideAtlas:F8WFC4}; KW Reference proteome {ECO:0000313|Proteomes:UP000005640}; KW Signal {ECO:0000256|SAM:SignalP}. FT SIGNAL 1 37 {ECO:0000256|SAM:SignalP}. FT CHAIN 38 95 {ECO:0000256|SAM:SignalP}. FT /FTId=PRO_5003385626. FT DOMAIN 42 82 IGv. {ECO:0000259|Pfam:PF07686}. SQ SEQUENCE 95 AA; 9804 MW; 9EF7DC2A14FF4789 CRC64; MAASAGAGAV IAAPDSRRWL WSVLAAALGL LTAGVSALEV YTPKEIFVAN GTQGKLTCKF KSTSTTGGLT SVSWSFQPEG ADTTVSRICL CFQFG //