ID   F8WEK9_HUMAN            Unreviewed;       115 AA.
AC   F8WEK9;
DT   21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT   21-SEP-2011, sequence version 1.
DT   16-JAN-2019, entry version 48.
DE   SubName: Full=Serotransferrin {ECO:0000313|Ensembl:ENSP00000401505};
GN   Name=TF {ECO:0000313|Ensembl:ENSP00000401505};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000401505, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000401505, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16641997; DOI=10.1038/nature04728;
RA   Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R.,
RA   Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R.,
RA   Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V.,
RA   Hume J., Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R.,
RA   Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B.,
RA   Nazareth L.V., Scott G., Sodergren E., Song X.Z., Steffen D., Wei S.,
RA   Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q.,
RA   Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z.,
RA   Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C.,
RA   Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G.,
RA   Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B.,
RA   Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R.,
RA   Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J.,
RA   Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O., Palmeiri A.,
RA   Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B.,
RA   Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H.,
RA   Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J.,
RA   Wang J., Wang Q., Williams G.A., Wong G.K., Yao Z., Zhang J.,
RA   Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H.,
RA   Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G.,
RA   Gibbs R.A.;
RT   "The DNA sequence, annotation and analysis of human chromosome 3.";
RL   Nature 440:1194-1198(2006).
RN   [2] {ECO:0000213|PubMed:21269460}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA   Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P.,
RA   Burckstummer T., Bennett K.L., Superti-Furga G., Colinge J.;
RT   "Initial characterization of the human central proteome.";
RL   BMC Syst. Biol. 5:17-17(2011).
RN   [3] {ECO:0000313|Ensembl:ENSP00000401505}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AC080128; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC083905; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; F8WEK9; -.
DR   jPOST; F8WEK9; -.
DR   MaxQB; F8WEK9; -.
DR   PeptideAtlas; F8WEK9; -.
DR   PRIDE; F8WEK9; -.
DR   Ensembl; ENST00000414694; ENSP00000401505; ENSG00000091513.
DR   UCSC; uc062nzp.1; human.
DR   EuPathDB; HostDB:ENSG00000091513.14; -.
DR   HGNC; HGNC:11740; TF.
DR   OpenTargets; ENSG00000091513; -.
DR   eggNOG; ENOG410IEAI; Eukaryota.
DR   eggNOG; ENOG410XQ36; LUCA.
DR   GeneTree; ENSGT00940000154388; -.
DR   ChiTaRS; TF; human.
DR   Proteomes; UP000005640; Chromosome 3.
DR   Bgee; ENSG00000091513; Expressed in 193 organ(s), highest expression level in inferior vagus X ganglion.
DR   ExpressionAtlas; F8WEK9; baseline and differential.
DR   GO; GO:0004857; F:enzyme inhibitor activity; IEA:InterPro.
DR   InterPro; IPR029785; ICA.
DR   InterPro; IPR001156; Transferrin-like_dom.
DR   PANTHER; PTHR11485:SF20; PTHR11485:SF20; 1.
DR   Pfam; PF00405; Transferrin; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:F8WEK9,
KW   ECO:0000213|PeptideAtlas:F8WEK9};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     19       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        20    115       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003379477.
FT   DOMAIN       25     74       Transferrin-like.
FT                                {ECO:0000259|Pfam:PF00405}.
SQ   SEQUENCE   115 AA;  12508 MW;  CFE7A6050FB7A707 CRC64;
     MRLAVGALLV CAVLGLCLAV PDKTVRWCAV SEHEATKCQS FRDHMKSVIP SDGPSVACVK
     KASYLDCIRA IAVSRCCLKE SGRKPYFLCF QSLWNNSLLT GKRSGCCDTG CRFGV
//