ID   F8WDX2_HUMAN            Unreviewed;        71 AA.
AC   F8WDX2;
DT   21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT   21-SEP-2011, sequence version 1.
DT   16-JAN-2019, entry version 44.
DE   SubName: Full=Interleukin-10 receptor subunit beta {ECO:0000313|Ensembl:ENSP00000414682};
GN   Name=IL10RB {ECO:0000313|Ensembl:ENSP00000414682};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000414682, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000414682, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=10830953; DOI=10.1038/35012518;
RG   Chromosome 21 mapping and sequencing consortium;
RA   Hattori M., Fujiyama A., Taylor T.D., Watanabe H., Yada T.,
RA   Park H.-S., Toyoda A., Ishii K., Totoki Y., Choi D.-K., Groner Y.,
RA   Soeda E., Ohki M., Takagi T., Sakaki Y., Taudien S., Blechschmidt K.,
RA   Polley A., Menzel U., Delabar J., Kumpf K., Lehmann R., Patterson D.,
RA   Reichwald K., Rump A., Schillhabel M., Schudy A., Zimmermann W.,
RA   Rosenthal A., Kudoh J., Shibuya K., Kawasaki K., Asakawa S.,
RA   Shintani A., Sasaki T., Nagamine K., Mitsuyama S., Antonarakis S.E.,
RA   Minoshima S., Shimizu N., Nordsiek G., Hornischer K., Brandt P.,
RA   Scharfe M., Schoen O., Desario A., Reichelt J., Kauer G., Bloecker H.,
RA   Ramser J., Beck A., Klages S., Hennig S., Riesselmann L., Dagand E.,
RA   Wehrmeyer S., Borzym K., Gardiner K., Nizetic D., Francis F.,
RA   Lehrach H., Reinhardt R., Yaspo M.-L.;
RT   "The DNA sequence of human chromosome 21.";
RL   Nature 405:311-319(2000).
RN   [2] {ECO:0000313|Ensembl:ENSP00000414682}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AP000295; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; F8WDX2; -.
DR   jPOST; F8WDX2; -.
DR   MaxQB; F8WDX2; -.
DR   PeptideAtlas; F8WDX2; -.
DR   Ensembl; ENST00000422891; ENSP00000414682; ENSG00000243646.
DR   UCSC; uc061zpq.1; human.
DR   EuPathDB; HostDB:ENSG00000243646.8; -.
DR   HGNC; HGNC:5965; IL10RB.
DR   OpenTargets; ENSG00000243646; -.
DR   eggNOG; ENOG410IER7; Eukaryota.
DR   eggNOG; ENOG410YTBJ; LUCA.
DR   GeneTree; ENSGT00940000158231; -.
DR   ChiTaRS; IL10RB; human.
DR   Proteomes; UP000005640; Chromosome 21.
DR   Bgee; ENSG00000243646; Expressed in 224 organ(s), highest expression level in sigmoid colon.
DR   ExpressionAtlas; F8WDX2; baseline and differential.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR003961; FN3_dom.
DR   InterPro; IPR036116; FN3_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   Pfam; PF01108; Tissue_fac; 1.
DR   SUPFAM; SSF49265; SSF49265; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     19       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        20     71       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003385600.
FT   DOMAIN       15     67       Fibronectin type-III.
FT                                {ECO:0000259|Pfam:PF01108}.
SQ   SEQUENCE   71 AA;  7935 MW;  C9C28054C7950C34 CRC64;
     MAWSLGSWLG GCLLVSALGM VPPPENVRMN SVNFKNILQW ESPAFAKGNL TFTAQYLSHY
     WTPWNASRST C
//