ID   F8WDW5_HUMAN            Unreviewed;       169 AA.
AC   F8WDW5;
DT   21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT   21-SEP-2011, sequence version 1.
DT   16-JAN-2019, entry version 39.
DE   SubName: Full=Prominin-2 {ECO:0000313|Ensembl:ENSP00000402753};
GN   Name=PROM2 {ECO:0000313|Ensembl:ENSP00000402753};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000402753, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000402753, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15815621; DOI=10.1038/nature03466;
RA   Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H.,
RA   Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M.,
RA   Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E.,
RA   Kremitzki C., Oddy L., Du H., Sun H., Bradshaw-Cordum H., Ali J.,
RA   Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C.,
RA   Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J.,
RA   Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A.,
RA   Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K.,
RA   Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M.,
RA   Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K.,
RA   McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C.,
RA   Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N.,
RA   Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M.,
RA   Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E.,
RA   Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P.,
RA   Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A.,
RA   Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A.,
RA   Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T.,
RA   Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D.,
RA   Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X.,
RA   McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C.,
RA   Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S.,
RA   Miller W., Eichler E.E., Bork P., Suyama M., Torrents D.,
RA   Waterston R.H., Wilson R.K.;
RT   "Generation and annotation of the DNA sequences of human chromosomes 2
RT   and 4.";
RL   Nature 434:724-731(2005).
RN   [2] {ECO:0000313|Ensembl:ENSP00000402753}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AC009238; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; F8WDW5; -.
DR   jPOST; F8WDW5; -.
DR   MaxQB; F8WDW5; -.
DR   PeptideAtlas; F8WDW5; -.
DR   PRIDE; F8WDW5; -.
DR   Ensembl; ENST00000431567; ENSP00000402753; ENSG00000155066.
DR   UCSC; uc061ltg.1; human.
DR   EuPathDB; HostDB:ENSG00000155066.15; -.
DR   HGNC; HGNC:20685; PROM2.
DR   OpenTargets; ENSG00000155066; -.
DR   eggNOG; KOG4331; Eukaryota.
DR   eggNOG; ENOG410XRG0; LUCA.
DR   GeneTree; ENSGT00530000063586; -.
DR   ChiTaRS; PROM2; human.
DR   Proteomes; UP000005640; Chromosome 2.
DR   Bgee; ENSG00000155066; Expressed in 181 organ(s), highest expression level in vagina.
DR   ExpressionAtlas; F8WDW5; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:InterPro.
DR   InterPro; IPR008795; Prominin.
DR   PANTHER; PTHR22730; PTHR22730; 1.
DR   Pfam; PF05478; Prominin; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:F8WDW5,
KW   ECO:0000213|PeptideAtlas:F8WDW5};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     19       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        20    169       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003379559.
SQ   SEQUENCE   169 AA;  17493 MW;  7000074600526485 CRC64;
     MKHTLALLAP LLGLGLGLAL SQLAAGATDC KFLGPAEHLT FTPAARARWL APRVRAPGLL
     DSLYGTVRRF LSVVQLNPFP SELVKALLNE LASVKVNEAE ARAGQWGSGH PSCPAACPGG
     AVRGGLRGMR CDRGPLPAAG AHCRALLLLL PLPPALRGTS EDRAQGAGL
//