ID   F8WD58_HUMAN            Unreviewed;       232 AA.
AC   F8WD58;
DT   21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT   21-SEP-2011, sequence version 1.
DT   16-JAN-2019, entry version 49.
DE   SubName: Full=Contactin-4 {ECO:0000313|Ensembl:ENSP00000396719};
GN   Name=CNTN4 {ECO:0000313|Ensembl:ENSP00000396719};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000396719, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000396719, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16641997; DOI=10.1038/nature04728;
RA   Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R.,
RA   Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R.,
RA   Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V.,
RA   Hume J., Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R.,
RA   Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B.,
RA   Nazareth L.V., Scott G., Sodergren E., Song X.Z., Steffen D., Wei S.,
RA   Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q.,
RA   Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z.,
RA   Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C.,
RA   Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G.,
RA   Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B.,
RA   Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R.,
RA   Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J.,
RA   Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O., Palmeiri A.,
RA   Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B.,
RA   Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H.,
RA   Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J.,
RA   Wang J., Wang Q., Williams G.A., Wong G.K., Yao Z., Zhang J.,
RA   Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H.,
RA   Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G.,
RA   Gibbs R.A.;
RT   "The DNA sequence, annotation and analysis of human chromosome 3.";
RL   Nature 440:1194-1198(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000396719}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AC018842; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC022008; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC024057; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC026882; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC066608; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC087427; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF454900; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF457532; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; F8WD58; -.
DR   SMR; F8WD58; -.
DR   jPOST; F8WD58; -.
DR   PeptideAtlas; F8WD58; -.
DR   PRIDE; F8WD58; -.
DR   Ensembl; ENST00000427741; ENSP00000396719; ENSG00000144619.
DR   UCSC; uc062gbm.1; human.
DR   EuPathDB; HostDB:ENSG00000144619.14; -.
DR   HGNC; HGNC:2174; CNTN4.
DR   OpenTargets; ENSG00000144619; -.
DR   eggNOG; KOG3513; Eukaryota.
DR   eggNOG; ENOG410XSVG; LUCA.
DR   GeneTree; ENSGT00940000155198; -.
DR   ChiTaRS; CNTN4; human.
DR   Proteomes; UP000005640; Chromosome 3.
DR   Bgee; ENSG00000144619; Expressed in 165 organ(s), highest expression level in thoracic aorta.
DR   ExpressionAtlas; F8WD58; baseline and differential.
DR   GO; GO:0007411; P:axon guidance; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   Gene3D; 2.60.40.10; -; 2.
DR   InterPro; IPR033007; Contactin-4.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR013098; Ig_I-set.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR003598; Ig_sub2.
DR   PANTHER; PTHR43905:SF7; PTHR43905:SF7; 1.
DR   Pfam; PF07679; I-set; 1.
DR   SMART; SM00409; IG; 2.
DR   SMART; SM00408; IGc2; 1.
DR   SUPFAM; SSF48726; SSF48726; 2.
DR   PROSITE; PS50835; IG_LIKE; 2.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:F8WD58,
KW   ECO:0000213|PeptideAtlas:F8WD58};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     18       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        19    232       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003385496.
FT   DOMAIN       32    117       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   DOMAIN      122    207       Ig-like. {ECO:0000259|PROSITE:PS50835}.
SQ   SEQUENCE   232 AA;  26168 MW;  D7240EF4EACC429E CRC64;
     MRLPWELLVL QSFILCLADD STLHGPIFIQ EPSPVMFPLD SEEKKVKLNC EVKGNPKPHI
     RWKLNGTDVD TGMDFRYSVV EGSLLINNPN KTQDAGTYQC TATNSFGTIV SREAKLQFAY
     LDNFKTRTRS TVSVRRGQGM VLLCGPPPHS GELSYAWIFN EYPSYQDNRR FVSQETGNLY
     IAKVEKSDVG NYTCVVTNTV TNHKVLGPPT PLILRNDVQY QLLSGEELME SQ
//