ID   F8WCI6_HUMAN            Unreviewed;       120 AA.
AC   F8WCI6;
DT   21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT   21-SEP-2011, sequence version 1.
DT   16-JAN-2019, entry version 48.
DE   SubName: Full=Serotransferrin {ECO:0000313|Ensembl:ENSP00000418396};
GN   Name=TF {ECO:0000313|Ensembl:ENSP00000418396};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000418396, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000418396, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16641997; DOI=10.1038/nature04728;
RA   Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R.,
RA   Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R.,
RA   Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V.,
RA   Hume J., Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R.,
RA   Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B.,
RA   Nazareth L.V., Scott G., Sodergren E., Song X.Z., Steffen D., Wei S.,
RA   Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q.,
RA   Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z.,
RA   Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C.,
RA   Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G.,
RA   Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B.,
RA   Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R.,
RA   Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J.,
RA   Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O., Palmeiri A.,
RA   Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B.,
RA   Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H.,
RA   Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J.,
RA   Wang J., Wang Q., Williams G.A., Wong G.K., Yao Z., Zhang J.,
RA   Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H.,
RA   Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G.,
RA   Gibbs R.A.;
RT   "The DNA sequence, annotation and analysis of human chromosome 3.";
RL   Nature 440:1194-1198(2006).
RN   [2] {ECO:0000213|PubMed:21269460}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA   Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P.,
RA   Burckstummer T., Bennett K.L., Superti-Furga G., Colinge J.;
RT   "Initial characterization of the human central proteome.";
RL   BMC Syst. Biol. 5:17-17(2011).
RN   [3] {ECO:0000313|Ensembl:ENSP00000418396}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AC080128; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC083905; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; F8WCI6; -.
DR   jPOST; F8WCI6; -.
DR   MaxQB; F8WCI6; -.
DR   PeptideAtlas; F8WCI6; -.
DR   PRIDE; F8WCI6; -.
DR   Ensembl; ENST00000494430; ENSP00000418396; ENSG00000091513.
DR   UCSC; uc062nzq.1; human.
DR   EuPathDB; HostDB:ENSG00000091513.14; -.
DR   HGNC; HGNC:11740; TF.
DR   OpenTargets; ENSG00000091513; -.
DR   eggNOG; ENOG410IEAI; Eukaryota.
DR   eggNOG; ENOG410XQ36; LUCA.
DR   GeneTree; ENSGT00940000154388; -.
DR   ChiTaRS; TF; human.
DR   Proteomes; UP000005640; Chromosome 3.
DR   Bgee; ENSG00000091513; Expressed in 193 organ(s), highest expression level in inferior vagus X ganglion.
DR   ExpressionAtlas; F8WCI6; baseline and differential.
DR   GO; GO:0004857; F:enzyme inhibitor activity; IEA:InterPro.
DR   InterPro; IPR029785; ICA.
DR   InterPro; IPR001156; Transferrin-like_dom.
DR   PANTHER; PTHR11485:SF20; PTHR11485:SF20; 1.
DR   Pfam; PF00405; Transferrin; 1.
DR   PRINTS; PR00422; TRANSFERRIN.
DR   SMART; SM00094; TR_FER; 1.
DR   PROSITE; PS51408; TRANSFERRIN_LIKE_4; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:F8WCI6,
KW   ECO:0000213|PeptideAtlas:F8WCI6};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     19       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        20    120       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003379451.
FT   DOMAIN       25    120       Transferrin-like.
FT                                {ECO:0000259|PROSITE:PS51408}.
SQ   SEQUENCE   120 AA;  12789 MW;  3D95F7FD22D0976E CRC64;
     MRLAVGALLV CAVLGLCLAV PDKTVRWCAV SEHEATKCQS FRDHMKSVIP SDGPSVACVK
     KASYLDCIRA IAANEADAVT LDAGLVYDAY LAPNNLKPVV AEFYGSKEDF LLCCCCGEEG
//