ID   F8WBM4_HUMAN            Unreviewed;       152 AA.
AC   F8WBM4;
DT   21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT   21-SEP-2011, sequence version 1.
DT   05-DEC-2018, entry version 48.
DE   SubName: Full=Follicle-stimulating hormone receptor {ECO:0000313|Ensembl:ENSP00000405775};
GN   Name=FSHR {ECO:0000313|Ensembl:ENSP00000405775};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000405775, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000405775, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15815621; DOI=10.1038/nature03466;
RA   Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H.,
RA   Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M.,
RA   Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E.,
RA   Kremitzki C., Oddy L., Du H., Sun H., Bradshaw-Cordum H., Ali J.,
RA   Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C.,
RA   Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J.,
RA   Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A.,
RA   Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K.,
RA   Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M.,
RA   Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K.,
RA   McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C.,
RA   Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N.,
RA   Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M.,
RA   Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E.,
RA   Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P.,
RA   Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A.,
RA   Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A.,
RA   Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T.,
RA   Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D.,
RA   Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X.,
RA   McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C.,
RA   Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S.,
RA   Miller W., Eichler E.E., Bork P., Suyama M., Torrents D.,
RA   Waterston R.H., Wilson R.K.;
RT   "Generation and annotation of the DNA sequences of human chromosomes 2
RT   and 4.";
RL   Nature 434:724-731(2005).
RN   [2] {ECO:0000313|Ensembl:ENSP00000405775}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AC007189; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC079394; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC092533; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; F8WBM4; -.
DR   PRIDE; F8WBM4; -.
DR   Ensembl; ENST00000419927; ENSP00000405775; ENSG00000170820.
DR   UCSC; uc061jay.1; human.
DR   EuPathDB; HostDB:ENSG00000170820.11; -.
DR   HGNC; HGNC:3969; FSHR.
DR   OpenTargets; ENSG00000170820; -.
DR   eggNOG; KOG2087; Eukaryota.
DR   eggNOG; ENOG410XR1T; LUCA.
DR   GeneTree; ENSGT00940000158952; -.
DR   ChiTaRS; FSHR; human.
DR   Proteomes; UP000005640; Chromosome 2.
DR   Bgee; ENSG00000170820; Expressed in 52 organ(s), highest expression level in lower esophagus muscularis layer.
DR   ExpressionAtlas; F8WBM4; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:InterPro.
DR   GO; GO:0004963; F:follicle-stimulating hormone receptor activity; IEA:InterPro.
DR   Gene3D; 3.80.10.10; -; 1.
DR   InterPro; IPR002272; FSH_rcpt.
DR   InterPro; IPR026906; LRR_5.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR000372; LRRNT.
DR   InterPro; IPR034298; TSHR/LHCGR/FSHR.
DR   PANTHER; PTHR24372; PTHR24372; 1.
DR   PANTHER; PTHR24372:SF5; PTHR24372:SF5; 1.
DR   Pfam; PF13306; LRR_5; 1.
DR   Pfam; PF01462; LRRNT; 1.
DR   PRINTS; PR01143; FSHRECEPTOR.
DR   SMART; SM00013; LRRNT; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Leucine-rich repeat {ECO:0000256|SAAS:SAAS00619388};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Repeat {ECO:0000256|SAAS:SAAS00619387};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     17       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        18    152       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003379655.
FT   DOMAIN       17     50       LRRNT. {ECO:0000259|SMART:SM00013}.
SQ   SEQUENCE   152 AA;  17142 MW;  37DE330ACC08650C CRC64;
     MALLLVSLLA FLSLGSGCHH RICHCSNRVF LCQESKVTEI PSDLPRNAIE LRFVLTKLRV
     IQKGAFSGFG DLEKIEISQN DVLEVIEADV FSNLPKLHEI RIEKANNLLY INPEAFQNLP
     NLQYLSFSSF VLENAKVENG DHRAFSDRTN AL
//